Drug Discovery & Pharmaceuticals

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A simple route for synthesizing fungal compound and its derivatives

The solutions to many of humanity's problems can be found within nature. For instance, who could have guessed that an antibiotic as powerful as penicillin would be found in a common mold, or that the drug aspirin would be derived from the bark of the willow tree?

From Tokyo University of Science 10 Feb 2022

Tropical sea anemone stings could hold key to new pain-relieving drugs

QUT PhD researcher Lauren Ashwood has studied sea anemones' venom makeup extensively, in particular, Telmatactis stephensoni a reef-based sea anemone that can grow from 8 to 10 cm.

8 Feb 2022

San Antonio researchers report a new mechanistic target for leukemia drug development

Scientists at The University of Texas Health Science Center at San Antonio believe it may be possible to prevent DNA changes driven by two proteins highly active in leukemia and other cancers.

7 Feb 2022

Researchers discover a sustainable approach for drug development

Although several people think of medicines as purely synthetic compounds, nature is an important element of most of the medications humans depend on.

4 Feb 2022

Research highlights how carnosic acid found in rosemary inhibits SARS-CoV-2 infection

Scripps Research scientists have discovered evidence that a chemical present in rosemary might be a two-pronged weapon against SARS-CoV-2.

4 Feb 2022

Researchers build rapid-acting antidepressant compounds that are non-hallucinogenic

The World Health Organization estimates that nearly 280 million people worldwide suffer from depression.

2 Feb 2022

MIT researchers develop new way to deliver RNA in a capsule

Like most vaccines, RNA vaccines have to be injected, which can be an obstacle for people who fear needles. Now, a team of MIT researchers has developed a way to deliver RNA in a capsule that can be swallowed, which they hope could help make people more receptive to them.

1 Feb 2022

Leukemia-on-a-chip; The Future of Preventing Therapy Resistance?

We speak to Dr. Chao Ma, one of the speakers at SLAS 2022, about his groundbreaking 'leukemia-on-a-chip' technology and its future within therapy resistance.

From Society for Laboratory Automation and Screening (SLAS) 27 Jan 2022

Culturing marine sponge cells in 3D could scale-up production of biomass, bioactive metabolites

There are more than 9,000 species of marine sponges (Phylum Porifera) worldwide, which are a source of novel natural products.

25 Jan 2022

Peptide-enhanced, biological cancer drug may help treat breast cancer metastasis to bone

A moderate amount of a peptide-enhanced, biological cancer drug goes a long way in treating breast cancers that metastasize to the bone.

25 Jan 2022

Virologists identify a dual-action drug effective against SARS-CoV-2

A research team discovered a new dual attack mode of action while working on the development of a therapeutic candidate against SARS-CoV-2 infections.

20 Jan 2022

Evaporators assist academic drug discovery

BioChromato Inc reports how the renowned Chemistry Research Laboratories (CRL) at Oxford University (UK) are using several Smart Evaporator C1 units to support their drug discovery activities in therapeutic areas including oncology and regenerative medicine.

From BioChromato Inc. 19 Jan 2022

Using E.Coli to bring 3D Printing to Life

In this interview, we speak to Dr. Avinash Manjula Basavanna about his latest research that incorporated E. Coli to bring 3D printing materials to life.

From Massachusetts Institute of Technology (MIT) 13 Jan 2022

Experts develop AI-based binding site detection in nucleic acid macromolecules

Skoltech’s iMolecule group has created a solution that employs data on the structure of molecules to detect sites where possible drug candidates could interact.

13 Jan 2022

TetraScience announces 300% ARR growth and 2021 achievements; prepares for next phase of growth

TetraScience, the R&D Data Cloud Company, is pleased to share highlights from a record-breaking 2021 fiscal year, including 300% annual recurring revenue (ARR) growth, an $80M Series B funding round, and full operationalization of the Tetra Partner Network.

From TetraScience, Inc. 12 Jan 2022

Research explains how E4 peptide exerts antifibrotic effect and what makes it so effective

A research team at the Medical University of South Carolina led by Carol Feghali-Bostwick, Ph.D., reports in the Journal of Clinical Investigation Insight that the E4 peptide reverses fibrosis, or scarring, in human and mouse tissues by activating an antifibrotic pathway that is common to all organ systems.

11 Jan 2022

NeoCura and PhoreMost Announce Research Collaboration to Explore Novel Cancer Therapeutics

NeoCura and PhoreMost today announced an oncology drug discovery research collaboration.

From PhoreMost 11 Jan 2022

Researchers develop new CAR T cells that act as a "micropharmacy"

Immunotherapies called chimeric antigen receptor (CAR) T cells use genetically engineered versions of a patient's own immune cells to fight cancer. These treatments have energized cancer care, especially for people with certain types of blood cancers.

3 Jan 2022

"Heavy" hydrogen makes drugs to have a longer effect

Hydrogen (abbreviated "H") is the lightest of all elements. It usually consists only of a positively charged proton and a negatively charged electron and is also called protium in this form. But there are also two heavier hydrogen isotopes, deuterium and tritium.

24 Dec 2021

No conclusive evidence on the efficacy of green tea extracts in treating infectious disease

During the early days of the COVID-19 pandemic, there were few treatment options available. This led many to consider alternative medicines and herbal remedies to treat or prevent COVID-19.

17 Dec 2021