Genomics

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New links found between CRISPR, p53 and other cancer genes that could prevent accumulation of mutated cells

A protein that protects cells from DNA damage, p53, is activated during gene editing using the CRISPR technique.

18 Nov 2021

Genomic changes in advanced tumors reveal interactions with treatment

A novel way to look at cancer treatment resistance offers the possibility for identifying genetic mechanisms involved and alternative treatment approaches.

17 Nov 2021

Researchers discover a link between genetic variant and chronic hypersensitivity pneumonitis

Chronic hypersensitivity pneumonitis (CHP) is a long-term lung condition where the interstitial tissue surrounding the alveoli (air sacs) of the lungs becomes inflamed and develops "fibrosis", or scar tissue.

17 Nov 2021

Study identifies new gene that promotes progression to type 1 diabetes

When the pro-inflammatory pair, a receptor called CCR2 and its ligand CCL-2, get together, it increases the risk of developing type 1 diabetes, scientists report.

17 Nov 2021

Researchers perform targeted mutagenesis to prolong dormancy in barley

Unexpected rain before the harvest season leaves the farmer with a problem—untimely sprouting of barley.

17 Nov 2021

Researchers use DNA to track the genetic evolution, migration of chickpea

Scientists at the University of Saskatchewan are part of an international team that employed DNA to monitor the genetic evolution and migration of chickpea.

17 Nov 2021

New gene critical for daily behavioral rhythms discovered

Life is organized on a 24-hour schedule. Central to this regular rhythm is the circadian clock, timekeepers that are present in virtually every organ, tissue and cell type.

16 Nov 2021

CRISPR introduces potentially dangerous changes in cells, reveals research

New research revealed that gene editing, particularly gene knockout, with CRISPR-Cas9 can support cells with mutated gene forms associated with cancer.

15 Nov 2021

Study shows how a common gene mutation robs people of natural cancer protection

Scientists from the University of Virginia School of Medicine have identified how a common gene mutation deprives people of natural protection against cancer.

15 Nov 2021

New epigenetic editing technique could help treat a wide range of diseases

All the cells found in the body of an individual have the same genetic code.

15 Nov 2021

Pacific Ocean rockfish genomes offer new insights into the genetic determinants of aging

Genomes assembled from Pacific Ocean rockfishes – some species of which are among the longest-living vertebrates known – reveal new insights into the genetic determinants of aging.

12 Nov 2021

CRISPR screening identifies metabolic enzyme as new target for anti-inflammatory therapeutics

A metabolic enzyme that has been studied in cancer biology and is important for T cell function may offer a new target for anti-inflammatory therapeutics, Vanderbilt researchers have discovered.

12 Nov 2021

Using a new genetic technology to decipher intratumoral heterogeneity

Even within a single patient with cancer, there is a vast diversity of individual tumor cells, which display distinct behaviors related to growth, metastasis, and responses to chemotherapy.

12 Nov 2021

Study offers genetic clues on the fundamental development of anatomical appearance

Which genes control the defining features that make us look as we do? And how do they make it happen?

11 Nov 2021

Genetic testing underutilized in patients with cardiomyopathies and arrhythmias, study says

Heart failure and arrhythmia conditions are often considered as separate disorders, but genetic testing suggests there is much more overlap of these disorders than previously appreciated.

11 Nov 2021

Whole genome sequencing reveals chickpea's pan-genome

An international team of researchers from 41 organizations has assembled chickpea's pan-genome by sequencing the genomes of 3,366 chickpea lines from 60 countries.

11 Nov 2021

Scientists discover new genetic link to non-alcoholic inflammatory liver disease

Non-alcoholic fatty liver disease (NAFLD) is the accumulation of fat in the liver unrelated to alcohol abuse or other liver diseases.

11 Nov 2021

Research establishes a new understanding of how DNA methylation begins in plants

Crop improvement often involves the transfer of genetic material from one organism to another to produce a valuable trait. Some major examples of crops with these so-called "transgenes" include disease-resistant cotton and beta-carotene-enhanced golden rice.

10 Nov 2021

New program can help to correctly interpret the genetic code of newly sequenced organisms

Yekaterina "Kate" Shulgina was a first year student in the Graduate School of Arts and Sciences, looking for a short computational biology project so she could check the requirement off her program in systems biology. She wondered how genetic code, once thought to be universal, could evolve and change.

10 Nov 2021

Researchers identify a gene in wheat with profound effects on the production of seeds

Scientists from the John Innes Centre have identified a gene that has deep-rooted effects on seed production in wheat.

10 Nov 2021

Genomics

New links found between CRISPR, p53 and other cancer genes that could prevent accumulation of mutated cells

Genomic changes in advanced tumors reveal interactions with treatment

Researchers discover a link between genetic variant and chronic hypersensitivity pneumonitis

Study identifies new gene that promotes progression to type 1 diabetes

Researchers perform targeted mutagenesis to prolong dormancy in barley

Researchers use DNA to track the genetic evolution, migration of chickpea

New gene critical for daily behavioral rhythms discovered

CRISPR introduces potentially dangerous changes in cells, reveals research

Study shows how a common gene mutation robs people of natural cancer protection

New epigenetic editing technique could help treat a wide range of diseases

Pacific Ocean rockfish genomes offer new insights into the genetic determinants of aging

CRISPR screening identifies metabolic enzyme as new target for anti-inflammatory therapeutics

Using a new genetic technology to decipher intratumoral heterogeneity

Study offers genetic clues on the fundamental development of anatomical appearance

Genetic testing underutilized in patients with cardiomyopathies and arrhythmias, study says

Whole genome sequencing reveals chickpea's pan-genome

Scientists discover new genetic link to non-alcoholic inflammatory liver disease

Research establishes a new understanding of how DNA methylation begins in plants

New program can help to correctly interpret the genetic code of newly sequenced organisms

Researchers identify a gene in wheat with profound effects on the production of seeds

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