Genomics

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New technology efficiently detects gene mutation in blood with low error rate

Next-generation gene sequencing (NGS) technologies --in which millions of DNA molecules are simultaneously but individually analyzed-- theoretically provides researchers and clinicians the ability to noninvasively identify mutations in the blood stream.

5 May 2021

Study reveals genetic mutation associated with exfoliation syndrome

A team of researchers from the Agency for Science, Technology and Research's (A*STAR) Genome Institute of Singapore (GIS) and Bioprocessing Technology Institute (BTI), as well as Singapore Eye Research Institute (SERI), have identified a genetic mutation (functionally defective CYP39A1 gene) associated with exfoliation syndrome, the most common cause of glaucoma.

5 May 2021

Mutant corn gene found to increase the amount of sugars in the seeds and leaves

An abnormal accumulation of carbohydrates—starches and sugars—in the kernels and leaves of a mutant line of corn can be traced back to a single misregulated gene, and this finding provides insights into how the plant responds to stress.

From Penn State University 5 May 2021

Abnormal fetal development is regulated by genetics, not the intrauterine environment

The genetics of the placenta and fetus, not the mother’s intrauterine environment, regulate developmental abnormalities, including those that contribute to pregnancy loss.

5 May 2021

Study reveals relationship between form and function in the genetic material of dinoflagellates

A new study unfolds a longstanding puzzle about the connection between the function and form in the genetic material of a complex group of algae.

5 May 2021

New nanopore sequencing tool can identify the existence of nucleobases

Nanopore technology has the potential to enable the development of portable, low-cost, small devices capable of real-time DNA sequencing.

4 May 2021

New genetic database maps how immune disorders evolve

A first-of-its-kind genetic database for autoinflammatory and autoimmune disorders has been created by Japanese researchers.

4 May 2021

Researchers study the unique genomic organization of coral symbionts

According to recent findings, the genome of single-celled plankton, called dinoflagellates, is arranged in an extremely unusual and strange manner. The study results set the foundations for further research into these vital aquatic species and significantly broaden the understanding of what a eukaryotic genome can look like.

3 May 2021

New therapeutic target for patients with acute myeloid leukemia

According to a new study, targeting a pathway that is critical for the survival of some cases of acute myeloid leukemia could open up a new therapeutic route for patients.

3 May 2021

New gene therapy could help treat Duchenne muscular dystrophy

Researchers from UT Southwestern used a new kind of gene therapy to successfully treat mice with Duchenne muscular dystrophy (DMD), distinctively employing CRISPR-Cas9-based tools to restore a large section of the dystrophin protein missing in several DMD patients.

3 May 2021

Distinctive "spike" proteins of SARS-CoV-2 also play a key role in the disease

Scientists have known for a while that SARS-CoV-2's distinctive "spike" proteins help the virus infect its host by latching on to healthy cells.

3 May 2021

New gene editing tool helps analyze the mysterious quirk of bacteria

While the CRISPR-Cas9 gene editing system has become the poster child for innovation in synthetic biology, it has some major limitations.

3 May 2021

JIC-CIMMYT collaboration aims to find solutions for the world's wheat farmers and consumers

The John Innes Centre (JIC, UK) and the International Maize and Wheat Improvement Center (CIMMYT) -- two world class wheat research institutes -- have announced a strategic collaboration for joint research, knowledge sharing, and communications to further the global effort to develop the future of wheat.

30 Apr 2021

New integrative genetic screening technology offers insights into role of DNA accessibility in cancer

In a new resource for the scientific community, published today in Nature Biotechnology, researchers in the lab of Neville Sanjana, PhD, at the New York Genome Center (NYGC) and New York University (NYU) developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide.

30 Apr 2021

Geisinger receives $3.6 million from NCI to study the role of genetic variation in cancer

The National Cancer Institute, part of the National Institutes of Health, has awarded a 5-year, $3.6 million contract to Geisinger to study the role of genetic variation in cancer.

30 Apr 2021

Genetic evidence shows that cardio fitness influences coffee intake

If someone craves a strong caffeine hit or like the frothiness of a milky cappuccino, their daily coffee order can reveal more about their health than they realize.

29 Apr 2021

People with daytime sleepiness present shorter telomeres irrespective of whether they have obstructive sleep apnea

According to a recent study, people who self-report daytime sleepiness have shorter telomeres irrespective of whether they have obstructive sleep apnea.

29 Apr 2021

Study reveals SARS-CoV-2 spike protein can trigger long-term gene expression changes

According to the findings of a recent cell study, the SARS-CoV-2 spike protein can trigger long-term gene expression changes.

29 Apr 2021

Researchers discover new approach to reform plant breeding and genetics

The research was conducted at the Department of Food Science at the University of Copenhagen (UCPH FOOD) with professor emeritus Lars Munck as coordinator and builds on earlier work since 1963 at Svaloef Plant Breeding Institute and the Carlsberg Laboratory.

28 Apr 2021

New computer algorithm helps identify tumors with 'mismatch repair deficiencies'

A new way to identify tumors that could be sensitive to particular immunotherapies has been developed using data from thousands of NHS cancer patient samples sequenced through the 100,000 Genomes Project.

27 Apr 2021

Genomics

New technology efficiently detects gene mutation in blood with low error rate

Study reveals genetic mutation associated with exfoliation syndrome

Mutant corn gene found to increase the amount of sugars in the seeds and leaves

Abnormal fetal development is regulated by genetics, not the intrauterine environment

Study reveals relationship between form and function in the genetic material of dinoflagellates

New nanopore sequencing tool can identify the existence of nucleobases

New genetic database maps how immune disorders evolve

Researchers study the unique genomic organization of coral symbionts

New therapeutic target for patients with acute myeloid leukemia

New gene therapy could help treat Duchenne muscular dystrophy

Distinctive "spike" proteins of SARS-CoV-2 also play a key role in the disease

New gene editing tool helps analyze the mysterious quirk of bacteria

JIC-CIMMYT collaboration aims to find solutions for the world's wheat farmers and consumers

New integrative genetic screening technology offers insights into role of DNA accessibility in cancer

Geisinger receives $3.6 million from NCI to study the role of genetic variation in cancer

Genetic evidence shows that cardio fitness influences coffee intake

People with daytime sleepiness present shorter telomeres irrespective of whether they have obstructive sleep apnea

Study reveals SARS-CoV-2 spike protein can trigger long-term gene expression changes

Researchers discover new approach to reform plant breeding and genetics

New computer algorithm helps identify tumors with 'mismatch repair deficiencies'

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