Genomics

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Exposure to even low levels of lead can trigger epigenetic changes

A research team from Brazil and Portugal has identified a link between a microRNA (miRNA) and the presence of lead in an organism.

18 May 2021

Study identifies new epigenetic control pathways in multiple myeloma growth

An international group of researchers from Japan, the United States, and the UK studied the role of the histone demethylase KDM5A in multiple myeloma.

18 May 2021

Refreshers develop new DNA sequencing method

An international research team headed by Michal Hocek of the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) and Charles University and Ciara K. O'Sullivan of Universitat Rovira i Virgili (URV) in Spain have developed a novel method for labeling DNA, which in the future can be used for sequencing DNA by means of electrochemical detection.

18 May 2021

Study shows that inactivation of BRG1 leads to high genetic instability

Following the p53 tumor suppressor gene, the genes encoding two proteins of the SWI/SNF chromatin remodeling complex are the most often identified mutated.

17 May 2021

New CAD technology may open up new frontiers in genome research

A new Computer Aided Design (CAD) platform for whole genome design is being launched by two pioneers in the world of biotech: Genome Project-write (GP-write) and Twist Bioscience.

13 May 2021

Exploring the Genetic effects of Chernobyl Radiation

In this interview, AZoLifeSciences speaks to researchers from the National Cancer Institute about their latest research that investigated the genetic effects of Chernobyl radiation.

From National Cancer Institute (NCI) 13 May 2021

Researchers identify the biosynthesis mechanism of new DNA nucleobases

DNA is made up of nucleobases, which are depicted by the letters G, A, T, and C. They are the foundation of the genetic code.

From Institut Pasteur 13 May 2021

Metagenomic sequencing helps examine differences in the gut microbiome after injury

Researchers used metagenomic sequencing to identify variations in virus and bacterial populations that occur following spinal cord injury in mice.

13 May 2021

Research group reveals the essential role of Knl1 gene in plants

Dr. HAN Fangpu's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences reports the identification and functional study of the maize Knl1 gene in an article published online in PNAS.

12 May 2021

Scientists discover genes responsible for smoking-related decline in lung function

(Boston)--Chronic Obstructive Pulmonary Disease (COPD) is a disease caused by cigarette smoking that reduces lung function and causes difficulty breathing.

12 May 2021

Study analyzes how ecological specialization occurs in marine species

In contrast to terrestrial biota, aquatic species with planktonic larvae can sustain massive population sizes.

11 May 2021

Broader use of gene reserves helps conserve endangered species

According to studies, UK conservationists support the increased usage of Gene Conservation Units to help conserve some of the world’s rarest plants.

11 May 2021

The history of the Amazon Basin affects the distribution of manatees

All three species of manatee now present on Earth share a common ancestor from which they split some 6.5 million years ago, when a huge lake in Amazonia, then linked to the Caribbean, was cut off from the sea.

11 May 2021

Ulsan genome project reaches milestone of sequencing 10,000 whole genomes

UNIST and Ulsan City officially announced that their ambitious 10,000 Genome Project has finally reached the milestone of sequencing 10,000 whole genomes. On this day, they also held a declaration ceremony to commemorate the successful completion of the Ulsan 10,000 Genome Project, which was initiated in 2016 as part of the Genome Korea in Ulsan Project launched in 2015.

11 May 2021

São Tomé island has two different species of caecilians, shows new study

The Gulf of Guinea islands harbor an abundance of species found nowhere else on Earth. But for over 100 years, scientists have wondered whether or not a population of limbless, burrowing amphibians--known as caecilians--found on one of the islands is a single or multiple species.

11 May 2021

Mutations in GEMIN5 protein can cause rare genetic disorders in children

Researchers have discovered a genetic cause of an unusual neurological disorder characterized by developmental delay, known as ataxia.

From University of Pittsburgh 10 May 2021

Supercoiling characteristic of DNA's structure controls gene expression, research shows

The two meters of -stretched- DNA contained in human cells are continuously twisting and untwisting to give access to genetic information: when a gene is expressed to generate a protein, the two strands of DNA are separated to give access to all the machinery necessary for this expression, resulting in an excessive accumulation of coiling that needs to be resolved later.

10 May 2021