Genomics

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Hi-C Sequencing Unveils Phage-Host Dynamics in Soil Ecosystems

Bacteriophages-;viruses that infect bacteria-;are common in soil ecosystems.

14 Feb 2024

Unleashing the Potential of CRISPR-COPIES

The last ten years have seen tremendous advancements in CRISPR/Cas systems. These precise genome editing tools can be used for more than just gene therapy and transgenic crop development.

13 Feb 2024

Unlocking RNA Secrets: New Method Exposes Gene Expression's Hidden Hurdles

A new study demonstrates that a method may identify, for the first time, the frequency and precise location of a molecular occurrence known as "backtracking" across the genetic material (genome) of any species.

12 Feb 2024

GWAS Identifies Key Genetic Factors for Lassa Fever Susceptibility and Severity

While combing through the human genome in 2007, computational geneticist Pardis Sabeti made a discovery that would transform her research career.

9 Feb 2024

New Research Sheds Light on Divergent Roles of Paralogous RNA Helicases

Genetic expression, often leading to protein synthesis, requires a complex coordination of molecular machinery across several stages.

9 Feb 2024

Accelerating Genetic Research - The Story Behind One-pot DTECT

Dr Pierre Billon, PhD, grew increasingly frustrated with the lengthy turnaround times and high costs associated with obtaining genetic analysis from specialized private laboratories

8 Feb 2024

Scientists Predict DNA Mutations Causing Extra Fingers, Hearts

Our genomes provide the instructions for proper growth and development. Millions of genomic switches, known as enhancers, control the location and timing of gene expression, which in turn ensures the correct proteins are made in the right cells at the right time throughout our lives.

7 Feb 2024

New DNA Methylation-Based Analysis Provides Accurate Assessment of Pancreas Cell Composition

Research introduces new DNA methylation-based method for accurately assessing cell composition in the human pancreas, addressing a critical gap in diabetes research.

7 Feb 2024

Study Suggests a Link Between DNA Methylation Disorder and Epigenetic Clocks

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 2, entitled, "Epigenetic drift underlies epigenetic clock signals, but displays distinct responses to lifespan interventions, development, and cellular dedifferentiation."

7 Feb 2024

Outsmarting Viruses: Scientists Rewire Bacteria for Biomanufacturing Revolution

Genome engineering allows scientists to modify the genetic code of microbes. Now, researchers have engineered the genome of the bacterium Escherichia coli (E. coli) to make it immune to viral infections.

6 Feb 2024

New Model Predicts How Soil Microbes Impact Climate

Climate models are essential to predicting and addressing climate change, but can fail to adequately represent soil microbes, a critical player in ecosystem soil carbon sequestration that affects the global carbon cycle.

5 Feb 2024

Nanopore Sequencing Sheds Light on Plant Growth Trigger

Researchers from the Southern University of Science and Technology, under the direction of Prof. Xiaofeng Cao from the Chinese Academy of Sciences’ Institute of Genetics and Developmental Biology, recently reported a new understanding of how light affects plant growth in a study that was published in the PNAS.

5 Feb 2024

RIKEN Study Unravels Secrets of Plant Immune Receptors

Plants are continuously evolving new immune receptors to ever-changing pathogens. Researchers at the RIKEN Center for Sustainable Resource Science (CSRS) have traced the origin and evolutionary trajectory of plant immune receptors.

2 Feb 2024

Decoding Virus-Host Tug-of-War with RNA-Protein Interaction Mapping

The interplay between ribonucleic acid (RNA) and proteins is not only important for maintaining cellular homeostasis but is also at the center of the tug-of-war between virus and host.

2 Feb 2024

Enhanc3D Genomics Appoints Dr Daniel Turner as Chief Scientific Officer

Enhanc3D Genomics, a company developing disruptive technologies to unlock the 3D spatial genome for target and biomarker discovery, today announced the appointment of Dr Daniel Turner as Chief Scientific Officer (CSO). Dan’s deep expertise in genomics technology development and commercialisation will be key to achieving the next phase of Enhanc3D Genomics’ growth.

1 Feb 2024

Researchers Reveal Evolutionary Origin of Mysterious Immune System Molecule in Humans

Biological systems can behave as siblings in several ways, including by borrowing something and never giving it back.

31 Jan 2024

RNA-Seq Unveils Molecular Subtypes for Tailored Pediatric B-ALL Treatment

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, representing more than 30% of all pediatric cases.

31 Jan 2024

Gene Therapy Can Interrupt the Progression of Deadly Inherited Heart Condition

A new study in mice shows that replacement of a dysfunctional gene could prolong survival in some people with arrhythmogenic right ventricular cardiomyopathy (ARVC), a rare inherited disorder in which the muscular walls of the heart progressively weaken and put patients at risk of dangerous irregular heartbeats.

31 Jan 2024

51 Vertebrate Genomes Sequenced Rapidly, Offering a New Perspective on Human Evolutionary History

The mapping of genetic blueprints for 51 species, such as sharks, turtles, kangaroos, cats, penguins, and dolphins, has advanced the knowledge of evolution and the relationships between animals and people.

30 Jan 2024

SYCE2 Gene Variant Disrupts Alignment of Chromosomes, Potentially Leading to Pregnancy Loss

Scientists at deCODE genetics, a subsidiary of Amgen and their collaborators from Iceland, Denmark and USA published a study today in Nature Structural and Molecular Biology titled "Variant in the synaptonemal complex protein SYCE2 associates with pregnancy loss through effects on recombination".

30 Jan 2024