Genomics

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Large Study Finds 187 New Genetic Variants Linked to Prostate Cancer

A globe-spanning scientific team has compiled the most comprehensive list of genetic variants associated with prostate cancer risk -; 451 in all -; through a whole-genome analysis that ranks as the largest and most diverse investigation into prostate cancer genetics yet.

10 Nov 2023

Dissecting the Mechanisms Behind Selective Genomic Editing

A new study is in progress to unravel a fascinating biological mystery of how certain animals can naturally eliminate more than half of their genetic information during embryonic development.

10 Nov 2023

Examining the Link Between Sleep Alteration and Aging in Jewel Wasps

Parents of newborns might sense a rapid aging effect during the early months of sleepless nights. Currently, researchers at the University of Leicester are exploring the intriguing possibility that the key to a long and healthy life lies in a restful night's sleep and human DNA.

10 Nov 2023

Scientists Forge a Path to the World’s First Synthetic Yeast Genome

Researchers crafted a chromosome entirely from the ground up, paving the way for the creation of the inaugural synthetic yeast in the world.

9 Nov 2023

Challenging the Assumption of Genetic Homogeneity in European Ancestry

Previous studies studying the genomes of people with European heritage might have reported misleading results because they did not adequately account for population structure, according to a new study.

8 Nov 2023

Unearthing Beal’s Time Capsule: The 144-Year-Old Seed Experiment

In April of 2021, a clandestine gathering took place on the Michigan State University campus, where four plant scientists from the university unearthed a bottle filled with seeds that had been buried over 144 years ago by the renowned MSU botanist, William J. Beal.

8 Nov 2023

Genomic Sequencing Reveals Songbird’s Secrets

Researchers have deciphered the genetic foundation responsible for the striking diversity in body size that is evident among song sparrows, a cherished and widely recognized species of North American songbirds.

8 Nov 2023

Research Reveals the Genetic Basis for Song Sparrow Adaptation to Local Climate

Whole genome sequencing of North American song sparrows has revealed the genetic underpinnings for a stunning range of body sizes found throughout the bird's westernmost range-;an adaptation that may make the birds more resilient to climate change.

8 Nov 2023

Unraveling the Mysteries of Tar Spot Disease in Corn

In 2015, the first instances of tar spot were reported, marking the emergence of a devastating disease in corn.

7 Nov 2023

Unveiling the Role of Foxp3 in Shaping Chromatin Architecture of Regulatory T Cells

Regulatory T cells, or Tregs, represent a specialized class of immune cells dedicated to quelling immune responses and safeguarding the body against self-attack.

7 Nov 2023

Epidemiology and Genetic Underpinnings of Clonal Hematopoiesis

A comprehensive new study from deCODE genetics, a subsidiary of Amgen, published today in Nature Genetics, provides insights into the epidemiology and somatic and germline genetics of clonal hematopoiesis.

7 Nov 2023

Epigenetic Changes Drive Cancer Development

Every cell makes its own proteins by accessing the genetic information on its genes. Changes in this information, called mutations, may ruin the function of the affected proteins.

7 Nov 2023

Plants Exploit Randomness to Avoid Mitochondrial Damage

Humans wouldn't last long without plant mitochondria and chloroplasts. These essential compartments of plant cells famously capture sunlight and power plant life – and so, ultimately, provide all the food we eat.

7 Nov 2023

Novel Gene Therapy Targets Core Motor Symptoms of Parkinson’s Disease

A team of researchers from the Shenzhen Institute of Advanced Technology (SIAT) at the Chinese Academy of Sciences (CAS) and their collaborators have devised a gene therapy approach aimed at selectively manipulating the affected circuitry in Parkinson’s disease.

6 Nov 2023

Understanding the Dynamic Regulation of Manchette Microtubules in Sperm Development

A team of researchers, led by Wenxiang Meng from the Institute of Genetics and Developmental Biology at the Chinese Academy of Sciences, has demonstrated that the deletion of the calmodulin-regulated spectrin-associated protein 1 (CAMSAP1) gene in mice, which is associated with the minus ends of non-centrosomal microtubules, results in a condition known as oligoasthenoteratozoospermia.

6 Nov 2023

Fetal Kidney Atlas Sheds Light on Disease Origins and Kidney Health

Scientists have examined the gene expression patterns of single cells from 5 human fetal kidneys to create the most complete atlas of the fetal kidney to date.

6 Nov 2023

CRISPR-Cas9 Enzyme's Magnesium Role Unraveled in DNA Cutting

The gene-editing technology known as CRISPR has led to revolutionary changes in agriculture, health research and more.

6 Nov 2023

Exploring Z-RNA’s Role in Immune Response

Quentin Vicens, an Assistant Professor of Biology and Biochemistry at the University of Houston, has been granted $1.2 million by the National Institute of General Medical Sciences to investigate the enigmatic Z-RNA structure found within human cells.

3 Nov 2023

New Study Sheds Light on Evolution of Sex Differences in Animals

Researchers at the Francis Crick Institute and Heidelberg University in Germany have shown that sex differences in animals vary dramatically across species, organs and developmental stages, and evolve quickly at the gene level but slowly at the cell type level.

3 Nov 2023

Prime Editing and Base Editing Could Revolutionize Treatment for Phenylketonuria

Phenylketonuria (PKU) is a rare newborn genetic disease that impacts between 1 in 10,000 to 1 in 20,000 people, depending on the individuals' genetic ancestry. PKU causes an amino acid-;called phenylalanine (Phe)-;to build up in the bloodstream.

3 Nov 2023