Genomics

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Novel tool can efficiently map new genome sequences to a "pangenome"

Since the first sequencing of the human genome more than 20 years ago, the study of human genomes has relied almost exclusively on a single reference genome to which others are compared to identify genetic variations.

From University of California Santa Cruz 17 Dec 2021

Services to accelerate genome editing research

AMSBIO has expanded its range of custom gene editing services to complement its extensive portfolio of off-the-shelf CRISPR/Cas9 products.

From AMS Biotechnology 17 Dec 2021

Researchers develop novel technique to monitor remote immune mechanisms

The human immune system works hard to maintain an individual’s health and protect against viruses, bacteria, parasites, fungi, and cancerous cells.

17 Dec 2021

Study employs gene reactivation to treat Fragile X syndrome

Fragile X syndrome, or FXS—a principal genetic cause of autism—impacts around one in 6,000 females and one in 4,000 males.

17 Dec 2021

Adults with rare genetic changes have poorer health, says study

According to a study, grown-ups with certain genetic causes of mental health and other brain disorders had substantially increased rates of chronic disease.

17 Dec 2021

Lack of genetic switch results in malformations during embryonic development

A group of researchers identified how a minor disturbance in the activation mechanism of this gene triggers the origin of clubfoot, a common foot malformation.

17 Dec 2021

What Role do Genes Play in the Development of Antibodies?

In this interview, we speak to researchers from the University of Toronto about their latest research that investigated the role genes play in the development of antibodies.

From University of Toronto 16 Dec 2021

Study paves the way for more accurate prenatal genetic testing for congenital heart disease

One in every 100 babies is born with a congenital heart disease (CHD), and CHD is the major cause of death in newborns – however the genetic cause of these developmental disorders is not fully understood, hindering the development of accurate pre-natal genetic testing.

15 Dec 2021

Clemson-led research on unlocking the cotton genome bound for International Space Station

Clemson researcher Chris Saski admits sending the University's iconic Tiger Paw to space aboard a SpaceX Dragon spacecraft is, quite literally, "an out-of-this-world experience."

15 Dec 2021

Genetic mutation appears to be a predisposing factor for COPD independent of smoking

In 2019, the WHO positioned chronic obstructive pulmonary disease (COPD) third in the global ranking of causes of death.

From Institut Pasteur 15 Dec 2021

Detecting high-impact rare genetic variants in individuals with severe schizophrenia

New research published in the Proceedings of the National Academy of Sciences shows that examining genetic mutations in individuals with severe schizophrenia can improve the ability to detect disease-associated rare genetic variants.

15 Dec 2021

Gene writing helps develop advanced therapies safely and effectively

An international, multidisciplinary team of researchers from the Translational Synthetic Biology Laboratory at Pompeu Fabra University (Barcelona, Spain), led by Dr. Marc Güell, has published an article in the scientific journal Nature Communications.

14 Dec 2021

Study provides new insight into the genetics of severe schizophrenia

Columbia University researchers have determined that individuals who suffer from the most severe form of schizophrenia have a significantly higher number of rare mutations than more typical forms of the illness.

14 Dec 2021

Research reveals nutrient responses underpinning a potentially deadly, low-chlorophyll state in plants

Green is a color that is almost universally associated with plants-;for good reason. The green pigment chlorophyll is essential to plants' ability to generate food; but what happens if they don't have enough of it?

13 Dec 2021

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Clinician scientists and scientists from the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore, in collaboration with Singapore General Hospital, the National University Health System, Duke-NUS Medical School, Nanyang Technological University, and collaborators from China, Malaysia, Thailand and the Philippines, have described a dynamic genomic landscape of tumour heterogeneity in hepatocellular carcinoma (HCC).

13 Dec 2021

Genetic makeup of neuroblastoma shows marked spatial and temporal variability

Tumors are heterogeneous, which means that different parts of the same tumor can be genetically distinct. This phenomenon, known as intratumor heterogeneity, is steadily gaining in significance within the field of cancer research.

13 Dec 2021

New technology can help detect the activity of CRISPR gene editing tools

Detecting the activity of CRISPR gene editing tools in organisms with the naked eye and an ultraviolet flashlight is now possible using technology developed at the Department of Energy's Oak Ridge National Laboratory.

13 Dec 2021

New classification method divides breast cancers into 12 distinct biological groups

Researchers at UNC Lineberger Comprehensive Cancer Center have taken a major step forward in melding two key methods for studying breast cancer: one by genetic analysis and the second by looking at the architecture of cells, or their pathology.

9 Dec 2021

Study of people from diverse ancestries provides a powerful tool for predicting heart disease risk

In a large-scale study of people from diverse ancestries, researchers narrowed down the number of genomic variants that are strongly associated with blood lipid levels and generated a polygenic risk score to predict elevated low-density lipoprotein cholesterol levels, a major risk factor for heart disease.

From National Human Genome Research Institute (NHGRI) 9 Dec 2021

ASHG launches major initiative to understand, document experiences of past injustice in human genetics research

The American Society of Human Genetics today announced a major year-long initiative to understand and document experiences of past injustice, as well as progress toward justice, in the human genetics research field and the Society.

9 Dec 2021

Genomics

Novel tool can efficiently map new genome sequences to a "pangenome"

Services to accelerate genome editing research

Researchers develop novel technique to monitor remote immune mechanisms

Study employs gene reactivation to treat Fragile X syndrome

Adults with rare genetic changes have poorer health, says study

Lack of genetic switch results in malformations during embryonic development

What Role do Genes Play in the Development of Antibodies?

Study paves the way for more accurate prenatal genetic testing for congenital heart disease

Clemson-led research on unlocking the cotton genome bound for International Space Station

Genetic mutation appears to be a predisposing factor for COPD independent of smoking

Detecting high-impact rare genetic variants in individuals with severe schizophrenia

Gene writing helps develop advanced therapies safely and effectively

Study provides new insight into the genetics of severe schizophrenia

Research reveals nutrient responses underpinning a potentially deadly, low-chlorophyll state in plants

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Genetic makeup of neuroblastoma shows marked spatial and temporal variability

New technology can help detect the activity of CRISPR gene editing tools

New classification method divides breast cancers into 12 distinct biological groups

Study of people from diverse ancestries provides a powerful tool for predicting heart disease risk

ASHG launches major initiative to understand, document experiences of past injustice in human genetics research

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Latest in Genomics