Histology & Microscopy

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Visualizing the Molecular Interaction of Formins with Actin Filaments

Actin is a highly abundant protein that controls the shape and movement of all our cells. Actin achieves this by assembling into filaments, one actin molecule at a time.

17 Apr 2024

Study Reveals How Cells Recycle Proteins in Response to Nutrient Starvation

A new study details how nutrient-starved cells divert protein transport stations to cellular recycling centers to be broken down, highlighting a novel approach cells use to deal with stressful conditions.

15 Apr 2024

Unraveling the Key to Suppressing Protein Misfolding in Neurodegenerative Diseases

Proteins known as oligomeric chaperones help suppress the formation of misshaped proteins that cause a variety of degenerative and neurodegenerative diseases, such as Alzheimer's, Huntington's, and Parkinson's.

13 Apr 2024

Researchers Identify Protein Regulating Gas Vesicle Patterning in Bacteria

Gas vesicles are hollow structures made of protein found in the cells of certain microorganisms, and researchers at Rice University believe they can be programmed for use in biomedical applications.

30 Mar 2024

Cryo-EM Imaging Unveils Similar Protein Structures in Alzheimer's and Down Syndrome

More than 90% of people with Down syndrome, the most common chromosomal disorder in humans and the most frequent genetic cause of intellectual disability, are diagnosed with Alzheimer's disease by ages 55-60.

30 Mar 2024

Research Sheds Light on Blood Cell Production in Mouse Skeleton

Imagine being able to count the different types of blood cells being formed inside the tiny bones of a mouse and pinpointing the strings and clusters of cells within the bone marrow that are responsible for producing specific types of blood cells.

25 Mar 2024

Novel Imaging Technique Unveils Structural Details of Drug-Resistant Cancer Protein

Researchers have shown for the first time that a crucial interface in a protein that drives cancer growth could act as a target for more effective treatments.

20 Mar 2024

Research Uncovers Individuality in Roundworm Neural Circuits

Joint research led by Yu Toyoshima and Yuichi Iino of the University of Tokyo has demonstrated individual differences in and successfully extracted commonalities from the whole-brain activity of roundworms.

18 Mar 2024

Scientists Discover Dual Challenges in DNA Replication Process

Half a century ago, scientists Jim Watson and Alexey Olovnikov independently realized that there was a problem with how our DNA gets copied.

29 Feb 2024

Research Reveals Conserved Neutralizing Epitope in Herpesvirus gB Protein

Human herpesviruses comprise the alpha, beta, and gamma subfamilies and are a widely prevalent group of DNA-enveloped viruses, capable of establishing lifelong latent infections in humans and causing various diseases.

27 Feb 2024

Uncovering the Neural Basis of Goal-Directed Navigation in Fruit Fly Brains

When we walk down the street, we have an internal sense of which way we are heading, from looking at street signals and physical landmarks, and also a sense of where we'd like to go.

9 Feb 2024

Plant Study Reveals Novel Mechanism for Coordinating Cellular Responses to Stress

A team of researchers from the University of Massachusetts Amherst recently published a pioneering study that answers a central question in biology: how do organisms rally a wide range of cellular processes when they encounter a change-;either internally or in the external environment-;to thrive in good times or survive the bad times?

7 Feb 2024

Unveiling a Dynamic Mode of Force Transmission in Cells

Cell biology has possibly never jumped to the next level in the same way.

2 Feb 2024

Scientists Capture Microtubule Birth in Human Cells

Researchers at the Centre for Genomic Regulation (CRG) in Barcelona and the Spanish National Cancer Research Centre (CNIO) in Madrid have captured the world's first high-resolution images of the earliest moments of microtubule formation inside human cells.

2 Feb 2024

Mathematical Model Unravels Brain Connectivity

Across all species, the functioning of the brain relies on a complex network of connections that enables neurons to exchange information, governing both thought processes and physical activities.

18 Jan 2024

New Technology Unveils Secrets of Fragile Marine Creatures in Minutes

A University of Rhode Island professor of Ocean Engineering and Oceanography, along with a multidisciplinary research team from multiple institutions, successfully demonstrated new technologies that can obtain preserved tissue and high-resolution 3D images within minutes of encountering some of the most fragile animals in the deep ocean.

18 Jan 2024

New Technology Enables Minimally-Invasive, High-Resolution Recording of Brain Activity

Sensors built with a new manufacturing approach are capable of recording activity deep within the brain from large populations of individual neurons–with a resolution of as few as one or two neurons–in humans as well as a range of animal models, according to a study published in the Jan. 17, 2024 issue of the journal Nature Communications.

18 Jan 2024

Universal Networking Principles Wire Up Different Brains

A new study by physicists and neuroscientists from the University of Chicago, Harvard and Yale describes how connectivity among neurons comes about through general principles of networking and self-organization, rather than the biological features of an individual organism.

18 Jan 2024

Honeybees Directly Provide Nutrients to Gut Bacteria

Bacteria have adapted to all terrestrial environments. Some have evolved to survive in the gut of animals, where they play an important role for their host; they provide energy by degrading indigestible food, they train and regulate the immune system, they protect against invasion by pathogenic bacteria, and they synthesize neuroactive molecules that regulate the behavior and cognition of their host.

16 Jan 2024