Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Study reveals that gene variant regulates protein level to prevent blood clots in the lungs

The probability of blood clots in the lungs of very sick COVID-19 patients is influenced by a gene variant in the natural immune system. This is demonstrated in a new study published in Nature Immunology by researchers from Uppsala University and Karolinska Institutet.

1 Jun 2022

Research shows how current drugs impact bacterial physiology

Tuberculosis is a stubborn disease caused by even more stubborn bacteria. While many bacterial infections clear up within days of taking antibiotics, TB can take up to six months to clear up and, in some cases, never leave the human body. In 2020, it claimed 1.5 million lives, second only to COVID-19 in terms of infectious disease deaths.

1 Jun 2022

Damaged liver treated in perfusion machine for three days and then implanted into a cancer patient

The multidisciplinary Zurich research team Liver4Life has succeeded in doing something during a treatment attempt that had never been achieved in the history of medicine until now: it treated an originally damaged human liver in a machine for three days outside a body and then implanted the recovered organ into a cancer patient.

1 Jun 2022

New bio-mimicking enzyme shows promise in degrading lignin

A new artificial enzyme has shown it can chew through lignin, the tough polymer that helps woody plants hold their shape. Lignin also stores tremendous potential for renewable energy and materials.

31 May 2022

Study highlights the interaction between single-stranded DNA and the linker histone H1

Human DNA is neatly locked in place around a central disc in the tight quarters of the cell nucleus by H1 linker histone that helps shepherd DNA into the tidy chromatin fibers that make up chromosomes. The linker histone, on the other hand, is much more than a protein clip.

31 May 2022

Study shows how gene related to Nascimento Syndrome activates the cell response to stress

According to a Duke University study, a gene linked to severe learning disabilities in humans also plays a critical role in cells’ response to environmental stress.

31 May 2022

Endogenous retroviruses in the human genome are likely to pose a risk in regenerative medicine

Scientists from Kumamoto University used next-generation sequencing to analyze human endogenous retrovirus (HERV) integration sites and found that these primitive retroviruses can retrotranspose (DNA sequence insertion with RNA mediation) into iPS cells.

31 May 2022

Scientists develop powerful tools using CRISPR-Cas9 to repair genetic diseases

CRISPR has marked the beginning of a new era in genomic medicine. The popular CRISPR-Cas9 has generated plenty of potent methods for curing genetic diseases.

30 May 2022

Researchers discover a significant health food ingredient

Aggrecan, a significant component of proteoglycan (PG) in cartilaginous tissues with chondroitin sulfate (CS), is becoming more popular as a wellness food ingredient.

From Tokyo University of Science 30 May 2022

Researchers create human cornea-on-a-chip to check the therapeutic effect of MSC exosomes on corneal disorders

Ophthalmologists and researchers have been looking into mesenchymal stem cells (MSCs) with regenerative and differentiation capacities as a potential therapy option for corneal disorders.

30 May 2022

Researchers determine the novel medical target of angiogenesis for ccRCC patients

Research reported that the DMDRMR/miR-378a-5p/ DAB2IP axis enhances angiogenesis and sunitinib resistance, suggesting that it could be used for patients with ccRCC.

30 May 2022

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS) - a group of disorders where there is insufficient production of healthy mature blood cells in the bone marrow - and increasingly in other diseases, but their mechanism of action remains unclear.

From National University of Singapore (NUS) 27 May 2022

Researchers analyze gut microbiome with dietary fiber through ecological model

Dietary fiber is known to be beneficial to gut health. However, it has a wide range of effects on the composition and metabolic activity of the gut microbiome.

27 May 2022

Study uncovers how CD8+ T cells can divide and produce two distinct daughter cells

An immunological problem has been addressed by scientists at St. Jude Children’s Research Hospital. Despite being genetically identical, a CD8+ T cell can divide and produce two functionally different daughter cells.

27 May 2022

Researchers develop a new biochemical process to analyze plant immunity

Researchers from Germany’s Max Planck Institute for Plant Breeding Research (MPIPZ) and the University of Cologne have identified a new biochemical process that explains how immune proteins protect plants against invading microbes. Their results have been reported in Cell.

From The Max Planck Institute 27 May 2022

A novel mechanism shared by mutations in varied genes could help treat neurological diseases

Researchers at Tel Aviv University, led by Prof. Illana Gozes from the Department of Human Molecular Genetics and Biochemistry at the Sackler Faculty of Medicine and the Sagol School of Neuroscience, have unraveled a mechanism shared by mutations in the genes ADNP and SHANK3, which cause autism, schizophrenia, and other conditions.

25 May 2022

Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Study reveals that gene variant regulates protein level to prevent blood clots in the lungs

Research shows how current drugs impact bacterial physiology

Damaged liver treated in perfusion machine for three days and then implanted into a cancer patient

New bio-mimicking enzyme shows promise in degrading lignin

Study highlights the interaction between single-stranded DNA and the linker histone H1

Study shows how gene related to Nascimento Syndrome activates the cell response to stress

Endogenous retroviruses in the human genome are likely to pose a risk in regenerative medicine

Scientists develop powerful tools using CRISPR-Cas9 to repair genetic diseases

Researchers discover a significant health food ingredient

Researchers create human cornea-on-a-chip to check the therapeutic effect of MSC exosomes on corneal disorders

Researchers determine the novel medical target of angiogenesis for ccRCC patients

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

Researchers analyze gut microbiome with dietary fiber through ecological model

Study uncovers how CD8+ T cells can divide and produce two distinct daughter cells

Researchers develop a new biochemical process to analyze plant immunity

A novel mechanism shared by mutations in varied genes could help treat neurological diseases

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

Researchers devise a new treatment approach to cure aggressive brain tumors

New study explores how human plastins behave in cells

Research may lead to new therapies for metabolic disorders and other diseases

Omics eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Omics eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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