Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Manipulating immune cells to suppress the growth of some solid tumors

Cancer researchers at the Case Western Reserve University School of Medicine say they have successfully suppressed the growth of some solid tumors in research models by manipulating immune cells known as a macrophages.

21 Apr 2022

Little-known protein may play a role in frontotemporal lobar degeneration

Scientists have known for years that amyloid fibrils -; fibrous, ropelike structures formed by closely linked protein molecules -; are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders.

21 Apr 2022

Researchers discover how new techniques may alter the synaptic connection of neurons

The brain has the potential to change the way neurons communicate with one another. That is how it prevents out-of-control brain activity. Scientists have discovered a mechanism that plays a key role in this.

21 Apr 2022

Researchers analyze single-cell DNA sequencing for having a significant role in Alzheimer’s disease

The loss of functional neurons in the brain is a characteristic of Alzheimer’s disease. What, on the other hand, is the source of this loss?

21 Apr 2022

New protective mechanism against non-alcoholic fatty liver disease identified

Non-alcoholic fatty liver disease (NAFLD), commonly known as fatty liver disease, is a prevalent disease frequently seen in obese people. Having high fat content in the liver is detrimental as it is strongly associated with severe health problems like diabetes, high blood pressure, and liver cancer.

20 Apr 2022

Researchers may have identified a key intermediate in the transition from prokaryotes to eukaryotes

All modern organisms fall into two classes, eukaryotes and prokaryotes. Eukaryotes (from the Greek meaning "true kernel") have a cell nucleus that harbors most of the cell's genetic information and includes organisms such as humans, plants and fungi.

20 Apr 2022

Genomics provides a deeper understanding of the cause of hydrocephalus

The cerebral ventricles—four linked cavities of the brain that are packed with cerebrospinal fluid—become enlarged in hydrocephalus, or “water on the brain;” however, the cause is unknown in many instances.

20 Apr 2022

Zbtb38 removal results in early embryonic death

DNA methylation is a critical epigenetic alteration for mammalian development.

20 Apr 2022

Study identifies new targets for treating sorafenib-resistant hepatocellular carcinoma using CRISPR-Cas9 screening

This study is led by Xiujun Cai (Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine). Professor Xiujun Cai's research team screened the whole genome of hepatocellular carcinoma cells (HepG2) through CRISPR / cas9 system under sorafenib treatment, and screened the dominant gene in sorafenib resistance.

20 Apr 2022

Scientists reveal the origins and provide a detailed ID card of pancreatic endocrine stem cells

The pancreas is a key metabolic regulator. When pancreatic beta cells cease producing enough insulin, blood sugar levels rise dangerously — a phenomenon known as hyperglycemia — thus triggering diabetes.

20 Apr 2022

Stem cell-mediated gene therapy technique helps to boost bone regeneration

Mesenchymal stem cell-derived exosomes (MSC-Exo) have gained a lot of attention due to their “cell-free” treatments.

20 Apr 2022

Rewiring the inner workings of leukemia cells to reverse drug resistance

Researchers from Barts Cancer Institute at Queen Mary University of London have identified a way to reverse resistance to a group of cancer drugs, known as kinase inhibitors, in leukemia cells.

20 Apr 2022

Scientists discover an effective drug development candidate from rare actinomycetes

Researchers are rushing to review a group of bacteria known as actinomycetes, which are one of the most successful sources of treatment.

19 Apr 2022

Study shows how peptide inhibitor helps to treat Alzheimer’s and Huntington’s disease

According to the Alzheimer’s Association, around 11% of the population, comprising 65-year old and above—in the United States has been diagnosed with Alzheimer’s disease (AD), the most prevalent form of dementia that causes memory loss and cognitive impairment.

19 Apr 2022

Double-stranded RNA provoke bone loss during periodontitis

Researchers from Tokyo University of Agriculture and Technology have made a novel revelation about the processes of bone loss in gum disease (periodontitis).

19 Apr 2022

Researchers use CRISPR gene editing tool to analyze globin gene switching

CRISPR gene editing—a form of “molecular scissors”—was used by UNSW researchers to investigate how deletions in one section of the genome might impact the expression of surrounding genes.

From The University of New South Wales (UNSW) 19 Apr 2022

Cryo-EM reveals the structure of fermentation enzyme phosphoketolase

Pharmaceuticals, plastics, and other industries use enzymes to help synthesize molecular feedstocks.

19 Apr 2022

Vitamin E can reinvigorate dendritic cells to enhance immunotherapy responses

Combining a retrospective analysis of clinical records with in-depth laboratory studies, researchers at The University of Texas MD Anderson Cancer Center have discovered that vitamin E can enhance immunotherapy responses by stimulating the activity of dendritic cells in the tumor.

18 Apr 2022

Study shows how innate lymphoid cells may help to treat inflammatory bowel disease

A team of researchers at Sweden’s Karolinska Institutet studied how specific immune cells known as innate lymphoid cells (ILCs), which play a role in inflammatory bowel disease (IBD), evolve into mature cells.

18 Apr 2022

Researchers analyze the complex function of cyanobacteria and the regulation of the biological clock

Researchers aim to learn more about circadian rhythms, which are the 24-hour internal clock cycles of sleeping and waking that happens in all species, including humans, plants, fungi, and bacteria.

18 Apr 2022

Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Manipulating immune cells to suppress the growth of some solid tumors

Little-known protein may play a role in frontotemporal lobar degeneration

Researchers discover how new techniques may alter the synaptic connection of neurons

Researchers analyze single-cell DNA sequencing for having a significant role in Alzheimer’s disease

New protective mechanism against non-alcoholic fatty liver disease identified

Researchers may have identified a key intermediate in the transition from prokaryotes to eukaryotes

Genomics provides a deeper understanding of the cause of hydrocephalus

Zbtb38 removal results in early embryonic death

Study identifies new targets for treating sorafenib-resistant hepatocellular carcinoma using CRISPR-Cas9 screening

Scientists reveal the origins and provide a detailed ID card of pancreatic endocrine stem cells

Stem cell-mediated gene therapy technique helps to boost bone regeneration

Rewiring the inner workings of leukemia cells to reverse drug resistance

Scientists discover an effective drug development candidate from rare actinomycetes

Study shows how peptide inhibitor helps to treat Alzheimer’s and Huntington’s disease

Double-stranded RNA provoke bone loss during periodontitis

Researchers use CRISPR gene editing tool to analyze globin gene switching

Cryo-EM reveals the structure of fermentation enzyme phosphoketolase

Vitamin E can reinvigorate dendritic cells to enhance immunotherapy responses

Study shows how innate lymphoid cells may help to treat inflammatory bowel disease

Researchers analyze the complex function of cyanobacteria and the regulation of the biological clock

Omics eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Omics eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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