Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Rising Prevalence of Chronic Rhinosinusitis in Japan: Causes and Implications

Chronic rhinosinusitis (CRS) is an inflammatory condition affecting the nasal cavity and sinuses, which can be categorized into eosinophilic and non-eosinophilic subtypes.

7 Nov 2023

Unveiling the Role of Foxp3 in Shaping Chromatin Architecture of Regulatory T Cells

Regulatory T cells, or Tregs, represent a specialized class of immune cells dedicated to quelling immune responses and safeguarding the body against self-attack.

7 Nov 2023

Understanding the Dynamic Regulation of Manchette Microtubules in Sperm Development

A team of researchers, led by Wenxiang Meng from the Institute of Genetics and Developmental Biology at the Chinese Academy of Sciences, has demonstrated that the deletion of the calmodulin-regulated spectrin-associated protein 1 (CAMSAP1) gene in mice, which is associated with the minus ends of non-centrosomal microtubules, results in a condition known as oligoasthenoteratozoospermia.

6 Nov 2023

Nucleotide Metabolite Controls DNA Repair and Cancer Sensitivity

Scientists have unraveled the mechanism by which a particular metabolite regulates DNA repair activity and the susceptibility of tissues to cancer treatment.

3 Nov 2023

Exploring Z-RNA’s Role in Immune Response

Quentin Vicens, an Assistant Professor of Biology and Biochemistry at the University of Houston, has been granted $1.2 million by the National Institute of General Medical Sciences to investigate the enigmatic Z-RNA structure found within human cells.

3 Nov 2023

Scientists Uncover New Insights into Cellular Recycling Process

Recycling is just as essential in cells as in our more familiar macroscopic world. Cells continuously generate waste products and accumulate damaged components while performing regular functions.

3 Nov 2023

Unlocking the Secrets of Memory: Key Protein Regulates Hippocampal Plasticity

Mount Sinai researchers have shed valuable light on the mechanism of a key protein that regulates the plasticity and function of the hippocampus, a key brain region involved in memory and learning, and that decreases with age in mice.

3 Nov 2023

New Methods to Modify Molecular Structure Could Lead to More Tailored Drugs

For years, the top desire among those engaged in the development of pharmaceutical drugs was to find a simple method for substituting a carbon atom with a nitrogen atom in a molecule.

2 Nov 2023

Study Identifies Significant Changes in Peptides During Pyroglutamination

Peptides are biomolecules formed when two or more amino acids that perform key functions in the human organism, such as hormones, neurotransmitters, painkillers and antibiotics, bind together. For this reason, they are much studied and used by the pharmaceutical industry, for example.

2 Nov 2023

Scientists Unlock the Structure of Vesicular Monoamine Transporter 2

Neurons talk to each other using chemical signals called neurotransmitters. Scientists at St. Jude Children's Research Hospital have drawn on structural biology expertise to determine structures of vesicular monoamine transporter 2 (VMAT2), a key component of neuronal communication.

2 Nov 2023

Novel Activation Mechanism for First Identified Oncogene

In the late 1970s, the link between the c-Src gene and cancer was unveiled, marking the identification of the inaugural oncogene.

1 Nov 2023

Developing New Strategies for Soybean Molecular Breeding

The soybean (Glycine max) stands as a significant economic crop, offering valuable resources such as edible oil, plant-based protein, and various essential nutrients for human consumption.

31 Oct 2023

Targeting eIF4A with Zotatifin: A Promising Strategy for TNBC Treatment

Enhancing treatment options for triple-negative breast cancer (TNBC), a highly aggressive tumor with a grim prognosis and limited therapeutic possibilities has proven to be a formidable challenge.

31 Oct 2023

New Modular Nanoparticle Technology Opens the Door to a Variety of Therapeutic Approaches

Engineers at the University of California San Diego have developed modular nanoparticles that can be easily customized to target different biological entities such as tumors, viruses or toxins.

31 Oct 2023

Revealing the Protein Secrets of Plant Root Sealing for Sustainable Agriculture

Scientists have uncovered a protein that plays a crucial role in sealing plant roots, thereby controlling the absorption of nutrients and water from the soil.

30 Oct 2023

Unlocking the Mystery of N-Terminal Acetylation’s Impact on Protein Degradation

Scientists at the University of Bergen (UiB) have discovered that proteins employ a shared chemical marker as a protective shield against degradation, thereby influencing their mobility and the aging process.

30 Oct 2023

Genetics can Improve the Diagnostic Value of Cyanobacterial Biomarkers

Cyanobacteria are a key species in Earth's history, as they introduced atmospheric oxygen for the first time. The analysis of their evolution therefore provides important insights into the formation of modern aerobic ecosystems.

30 Oct 2023

Uncovering New Insights Into Primate Brain Evolution

In a recent research investigation, scientists from Yale University unveiled the molecular pathways responsible for the developmental distinctions that set primates apart from mice.

27 Oct 2023