Advancements in three-dimensional (3D) organoid development represent a new frontier in drug discovery. Their capacity to self-organize and imitate functional organ cell types is widely considered a better representation of in vivo biology than traditional 2D monolayer cell cultures.
These advantages are seeing organoids becoming increasingly central to cancer research, stem cell research, neurobiology, and drug discovery. Three-dimensional organoids represent a valuable approach to biological research and drug development, as these new tools are helping researchers gain detailed insight into the mechanisms of tissue development and disease.
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Rapid developments in advanced cell technologies and the widespread need to generate models that more closely resemble in vivo tissue have seen organoids take on a pioneering role in drug discovery and disease modeling.
Three-dimensional organoids have been developed to represent various human organs, and their application is anticipated to continue growing over the coming years.
As their use becomes more widespread, organoids are expected to form the foundation of upcoming translational, precision, and regenerative medicine innovations.
This complimentary eBook from Molecular Devices offers a vital guide to employing organoids in drug discovery applications.
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