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Study shows strong link between genetic changes and cerebral palsy

Scientists have identified a strong connection between genetic modifications known to cause cerebral palsy and neurodevelopmental disabilities.

3 Feb 2021

New technique to improve genome editing technology

A group of scientists from Peter the Great St. Petersburg Polytechnic University (SPbPU), in association with collaborators from Belgium, has taken a step in the advancement of genome editing technologies.

3 Feb 2021

Genetic burden of retrogene mutations is greater than originally believed

According to a new study performed by researchers from the Max Planck Institute for Evolutionary Biology in Plön, Germany, and the Chinese Academy of Sciences in Beijing, the possible genetic burden of mutations emerging from retrogenes is considerably greater than originally believed.

3 Feb 2021

Scientists identify new drug target for treating Hutchinson-Gilford progeria syndrome

Researchers have discovered a promising treatment method for Hutchinson-Gilford progeria syndrome (HGPS)—a debilitating genetic disorder that accounts for rapid and premature aging in children.

3 Feb 2021

Advances in cancer research can expand effectiveness of immunotherapy

Scientists are hoping advances in cancer research could lead to a day when a patient's own immune system could be used to fight and destroy a wide range of tumors.

3 Feb 2021

Researchers discover hydrogen-producing enzyme group that resists oxygen attack

Hydrogen-producing enzymes are beacons of hope in biohydrogen research. However, they are so vulnerable to oxygen in the air that it has not been possible to exploit their potential on a larger scale.

3 Feb 2021

Hyperactive RANK protein could trigger autoimmune diseases

Autoimmune diseases, in which the body's own immune system attacks healthy tissue, can be life-threatening and can impact all organs.

3 Feb 2021

Researchers gain a deep insight into the evolutionary history of bitter receptors

To evaluate the chemical composition of food from a physiological point of view, it is important to know the functions of the receptors that interact with food ingredients. These include receptors for bitter compounds, which first evolved during evolution in bony fishes such as the coelacanth.

3 Feb 2021

Researchers study the formation of reinforced, patterned cell walls during proto-xylem development

Trees are by far the tallest organisms on Earth. Height growth is made possible by a specialized vascular system that conducts water from the roots to the leaves with high efficiency, while simultaneously providing stability.

3 Feb 2021

Breast cancer-on-a-chip for rapid screening of immunotherapeutic drugs

There are many mechanisms by which the body responds to foreign invaders. One of these involves the T-cells of the immune system, which have a number of different proteins on their surface called "checkpoint proteins."

3 Feb 2021

Robotic System for Ultra-High Throughput SARS-CoV-2 Testing

Ziath reports how it has worked with the Hubrecht Institute (Utrecht, Netherlands) which has developed a pioneering automated test robot, called STRIP-1, which can process up to 20,000 samples for SARS-CoV-2 testing in just 24 hours.

From Ziath Ltd 3 Feb 2021

Solid Phase Extraction Microplate Selection Guide

Porvair Sciences announce the availability of a new guide that makes selection of the optimum Solid Phase Extraction (SPE) microplate for your application both quick and easy.

From Porvair Sciences Limited 3 Feb 2021

Synthetic biomolecule resembles dual stimuli-responsive channel

For the first time, researchers from the Tokyo Institute of Technology (Tokyo Tech) and the University of Tokyo in Japan have produced a new artificial transmembrane ion channel—based on a naturally found transmembrane channel that plays a role in neuron signaling—that reacts to both electrical and chemical stimuli.

2 Feb 2021

Toxin-antitoxin systems negatively control plasmid replication

According to Thomas Wood, Biotechnology Endowed Chair and Professor of Chemical Engineering at the Penn State College of Engineering., toxin-antitoxin (TA) structures are currently known to adversely regulate the replication of plasmids.

From Penn State University 2 Feb 2021

Genome architectural changes linked to B cell-related blood cancers

Flaws in the way chromosomes are packed into antibody-producing B-cells seem to play a key role in the development of B-cell-related blood cancers.

2 Feb 2021

Study compiles scientific literature to identify trends in marine litter

That is the question that Prof. Alan Deidun, resident academic within the Department of Geosciences of the Faculty of Science, along with a cohort of high-profile co-authors, posed within a study recently published in the Microplastics and Nanoplastics journal.

2 Feb 2021

Noncoding RNA plays key role in sepsis, regulates inflammatory gene expression

Sepsis can result when the body’s immune response to a specific infection gets out of control.

From University of California Santa Cruz 2 Feb 2021

Land-based mitigation options can lead to carbon-neutral livestock systems

The land sector can strongly contribute to climate change mitigation if sustainable land-use options are applied. A study led by the CMCC Foundation highlights that land-based mitigation options at the small-scale landscape level can lead towards carbon-neutral livestock systems while providing an additional wide range of ecological, environmental, and socio-economic co-benefits at the local level.

2 Feb 2021

Severe genetic immunodeficiency reversed by a rare DNA change

Researchers have revealed how a rare DNA change rebalanced the immune system of patients with a life-threatening genetic immunodeficiency.

2 Feb 2021

Study describes dynamic link between protein folding and misfolding

Correct, or native, protein folding is essential for correct protein function. Protein misfolding can lead to the formation of amyloid fibrils, and amyloidosis, which is implicated in various human neurodegenerative diseases, including Parkinson's, Alzheimer's, and Huntington's diseases.

From Osaka University 2 Feb 2021