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Protein aggregation reduces elasticity of blood vessels during aging

Deposits of a protein called "Medin", which manifest in virtually all older adults, reduce the elasticity of blood vessels during aging and hence may be a risk factor for vascular dementia.

10 Sep 2020

Combining stem cell therapy with educational intervention can help children with autism

Results of a clinical trial released today in STEM CELLS Translational Medicine indicate that a combination of stem cell therapy and educational intervention can significantly help children with autism spectrum disorder (ASD).

10 Sep 2020

New multi-phase process upgrades the use of lignin as a next-generation fuel

A new low-temperature multi-phase process for upgrading lignin bio-oil to hydrocarbons could help expand use of the lignin, which is now largely a waste product left over from the productions of cellulose and bioethanol from trees and other woody plants.

10 Sep 2020

Wild relatives could help domestic crops adapt to climate change

Earth is getting hotter. Huge amounts of greenhouse gases are warming the planet and altering the climate. Heat waves are harsher. Droughts are longer. And some diseases and pests are stronger than ever.

10 Sep 2020

CRISPR in a Box: New educational gene editing tool kit

Introducing CRISPR in a Box™ - it's not a new crunchy cereal or the latest snack - it's an educational tool kit consisting of state-of-the-science gene editing technology that could be coming to a school near you.

10 Sep 2020

Study sheds new light on the evolution of gene expression patterns

Vertebrate organs are known to manage physiological activities, and the varied expression patterns of scores of genes govern the functions of organs.

10 Sep 2020

Protein inhibitors neutralize SARS-CoV-2 infection in cell culture

Using innovative computer-based approaches, researchers have developed protein inhibitors that block the interaction between the SARS-CoV-2 virus and human cell receptor ACE2.

10 Sep 2020

Researchers review the role of macrophage activation syndrome in COVID-19

A major percentage of COVID-19 cases have become so severe that hospital admissions have become mandatory for both monitoring and treatment.

10 Sep 2020

Novel tool helps select the best gene-editing option

Scientists have improved one of the biggest scientific advancement of the past decade.

10 Sep 2020

Researchers identify protein that makes cancer cells more aggressive

When Goping’s research team found that a protein was linked to poor outcomes in breast cancer patients, she wanted to find out the reason behind this.

10 Sep 2020

Novel method produces anti-inflammatory substances with controlled quality

Anti-inflammatory substances based on components of human cells could one day improve treatment in patients. Researchers at the Institute of Pharmacy at Martin Luther University Halle-Wittenberg (MLU) have developed a method for producing those substances with controlled quality.

10 Sep 2020

Neuronal connections that trigger insomnia linked to stress-induced changes in the immune system

Scientists at Cold Spring Harbor Laboratory and Stanford University have pinpointed the circuit in the brain that is responsible for sleepless nights in times of stress--and it turns out that circuit does more than make you toss and turn.

10 Sep 2020

Computer-designed proteins protect lab-grown human cells from SARS-CoV-2

Computer-designed small proteins have now been shown to protect lab-grown human cells from SARS-CoV-2, the coronavirus that causes COVID-19.

10 Sep 2020

Human evolution shaped by pathogens and cell-autonomous immunity

Every human cell harbors its own defenses against microbial invaders, relying on strategies that date back to some of the earliest events in the history of life, researchers report.

10 Sep 2020

Researchers develop a new synthesis method for efficient production of fluorinated alkenes

The Nagoya University Institute of Transformative Bio-Molecules (WPI-ITbM) research team of Professor Cathleen Crudden, Designated Lecturer Masakazu Nambo, JSPS Postdoctoral Fellow Yuki Maekawa and Associate Professor Daisuke Yokogawa have developed a new synthesis method for the efficient production of fluorinated alkenes.

10 Sep 2020

New research reveals role of arginine metabolism in plant morphogenesis

Arginine metabolism boosts to make a plant body complex, according to new research by a collaborative team from Exploratory Research Center on Life and Living Systems (ExCELLS), National Institute for Basic Biology, RIKEN, Rikkyo University, Toyohashi University of Technology, Yamagata University, Chiba University, Hokkaido University, and University of Tokyo in Japan.

10 Sep 2020

Researchers reconstruct the birth of a male sex chromosome in Atlantic herring

The evolution of sex chromosomes is of crucial importance in biology as it stabilises the mechanism underlying sex determination and usually results in an equal sex ratio.

10 Sep 2020

An efficient therapeutic strategy against KRAS mutant lung tumors in mice

The KRAS oncogene is involved in at least one fifth of all human cancers: KRAS mutations are directly responsible for 32% of lung tumors and 96% of pancreatic tumors.

10 Sep 2020

In-depth study of kidney tumors reveals novel markers of response to immunotherapy

Treatments for kidney cancer have improved considerably over the past few decades. In 1988, when Memorial Sloan Kettering oncologist Robert Motzer started researching the disease, the average survival was less than one year.

9 Sep 2020

Researchers explore link between uncontrolled inflammation and brain's immune cells

Inspired by the need for new and better therapies for neurodegenerative diseases, such as Parkinson's disease and Alzheimer's disease, Rutgers University researchers are exploring the link between uncontrolled inflammation within the brain and the brain's immune cells, known as microglia.

9 Sep 2020