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Study shows how cancer develops resistance to chemotherapy

Cancer's knack for developing resistance to chemotherapy has long been a major obstacle to achieving lasting remissions or cures. While tumors may shrink soon after chemotherapy, many times they eventually grow back.

24 Jul 2020

Study shows KBTBD2 gene plays a key role in regulating insulin sensitivity

Deleting a key gene in mice in just their fat made tissues throughout these animals insulin resistant, in addition to other effects, a new study by UT Southwestern researchers shows.

24 Jul 2020

New approach is more effective in treating certain blood cancers

Some of the most promising advances in cancer treatment have centered on immunotherapies that rev up a patient's immune system to attack cancer.

24 Jul 2020

Study shows the effectiveness of plant-based diets in controlling type 1 diabetes

Plant-based diets rich in whole carbohydrates can improve insulin sensitivity and other health markers in individuals with type 1 diabetes, according to two case studies published by researchers from the Physicians Committee for Responsible Medicine in the Journal of Diabetes & Metabolism.

24 Jul 2020

Epigenomic data can help characterize genes that play key role in cancer progression

As cancer cells evolve, many of their genes become overactive while others are turned down. These genetic changes can help tumors grow out of control and become more aggressive, adapt to changing conditions, and eventually lead the tumor to metastasize and spread elsewhere in the body.

From Massachusetts Institute of Technology (MIT) 24 Jul 2020

Less invasive imaging system can improve cancer diagnosis

Cancer diagnosis requires a lengthy process of multiple analyses of tissue biopsies, impeding the quick and early detection of cancers.

From Osaka University 24 Jul 2020

Fruit and vegetable byproducts have beneficial effects on gut microbiota

Fruit and vegetable byproducts have beneficial effects on the gut

23 Jul 2020

Study shows how the immune system attacks harmful viruses and bacteria

A new study has revealed how immune cells migrate to the lymph nodes and help attack harmful viruses and bacteria.

23 Jul 2020

Evaluating the impact of sugary and acidic drinks on tooth enamel

Using atomic force microscopy, researchers have quantitatively assessed the effect of sugary and acidic drinks on human tooth enamel at the nanoscale level.

23 Jul 2020

Study reveals the degradation mechanism of endoplasmic reticulum

A team of researchers have analyzed the degradation mechanism of the endoplasmic reticulum (ER) called ER-phagy.

23 Jul 2020

Climate change is influencing the spread of invasive marine species

What factors influence the spread of invasive animal species in our oceans? This question was the focus for a team of experts from the Alfred Wegener Institute, Helmholtz Centre for Polar and Marine Research (AWI), Bangor University (Wales, UK), and the University of Greifswald's Zoological Institute and Museum in the context of the DFG-sponsored Research Training Group 2010 RESPONSE (Biological Responses to Novel and Changing Environments).

23 Jul 2020

Study shows neo-self antibody as major cause of recurrent pregnancy loss

A research group centered around Kobe University Graduate School of Medicine's Professor YAMADA Hideto and Associate Professor TANIMURA Kenji (Department of Obstetrics and Gynecology), and Professor ARASE Hisashi et al. of Osaka University's Research Institute for Microbial Diseases have revealed for the first time in the world the high frequency of a novel autoantibody in women suffering from recurrent pregnancy loss.

23 Jul 2020

Eating chocolate is linked with reduced risk of heart disease

Eating chocolate at least once a week is linked with a reduced risk of heart disease, according to research published today in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology.

23 Jul 2020

Reactivating divergent signaling pathways to enhance cancer treatment

In order for cancer to form in the human body, normal cells must acquire multiple mutations before they develop toward the disease. It was previously believed that these mutations acted in concert in the progression of cancer.

23 Jul 2020

Study shows efficacy of L-Grb2 in preclinical models of ovarian and uterine cancer

The cover for issue 29 of Oncotarget features Figure 5, "In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model," by Lara, et al. which reported that adaptor proteins such as growth factor receptor-bound protein-2 play important roles in cancer cell signaling.

23 Jul 2020

Visual working memory exhibits hierarchical encoding of images

Researchers from HSE University and the University of California San Diego, Igor Utochkin and Timothy Brady, have found new evidence of hierarchical encoding of images in visual working memory.

23 Jul 2020

Researchers identify the role of calcium channel subunits in synapse development

The ability of the human brain to process and store information is determined to a large extent by the connectivity between nerve cells. Chemical synapses are very important in this context as they constitute the interface for the transmission of information between individual nerve cells.

23 Jul 2020

New startup launched to overcome the challenge of delivering next-generation therapeutics

Harvard University's Office of Technology Development (OTD) and the Harvard T.H. Chan School of Public Health today announced the launch of Vesigen Therapeutics, a startup company that aims to overcome the challenge of delivering next-generation therapeutics, such as gene-editing complexes, RNA molecules, and other large proteins, to intracellular targets in specific tissues of interest.

23 Jul 2020

Mitigating methane production by dairy cattle through selective breeding

Researchers in Spain propose mitigating methane production by dairy cattle through breeding. In an article appearing in the Journal of Dairy Science, scientists are targeting reduction of enteric methane in the breeding objectives for dairy cattle to select for animals that use feed more efficiently and thus produce less methane.

23 Jul 2020

Buckwheat-based diet increases protein production that helps enhance longevity

A healthy low-calorie diet that contains plant products can help us improve the level of sirtuin 1 (SIRT1) protein production that is known to increase life expectancy.

23 Jul 2020