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Scientists discover how abnormal proteins unleash latent toxicity in neurodegenerative diseases

Thanks to modern medicine, humans tend to live much longer than before. Unfortunately, this also opens a wider window to develop chronic diseases with late-onset, such as neurodegenerative diseases.

23 Nov 2020

Study identifies molecular mutation more common in African Americans with late-onset Alzheimer’s

Scientists have identified a molecular mechanism that leads to a “traffic jam” of enzymes, resulting in the accumulation of amyloid-beta.

19 Nov 2020

Scientists identify key source of sensory perception

The brain encodes information collected by our senses. However, to perceive our environment and to constructively interact with it, these sensory signals need to be interpreted in the context of our previous experiences and current aims.

17 Nov 2020

Astrocytes regulate inhibitory synapses by binding to neurons

In the orchestra of the brain, the firing of each neuron is controlled by two notes--excitatory and inhibitory-- that come from two distinct forms of a cellular structure called synapses.

16 Nov 2020

Genetically edited form of herpes simplex virus outperforms key vaccine candidate

A genetically edited form of a herpes simplex virus -- rewired to keep it from taking refuge in the nervous system and eluding an immune response -- has outperformed a leading vaccine candidate in a new study from the University of Cincinnati, Northwestern University and the University of Nebraska-Lincoln.

9 Nov 2020

Researchers create “developmental atlas” to classify the neurons of fruit flies

Using machine learning and gene sequencing, scientists from New York University have designed a “developmental atlas” of gene expression in neurons to classify over 250,000 neurons in the brains of fruit flies.

5 Nov 2020

New method sheds light on the neuronal mechanisms of fly motion vision

Where in a nerve cell is a certain receptor protein located? Without an answer to this question, it is difficult to draw firm conclusions about the function of this protein.

3 Nov 2020

Researchers receive $2.6 million grant to examine tau-glycan interactions involved in Alzheimer's disease

Tangles of misfolded tau proteins in the brain are closely associated with memory loss in patients with Alzheimer's disease.

29 Oct 2020

Scientists find sensor protein which enables normal functioning of bladder

A team co-led by scientists at Scripps Research has found that the main sensor protein enabling our sense of touch also underlies the feeling of having a full bladder and makes normal bladder function possible.

15 Oct 2020

New software helps analyze individual cells in virtual reality

New virtual reality software now enables scientists to “walk” inside and examine individual cells.

14 Oct 2020

Dopamine and serotonin found to be involved in perception, cognitive capacities

In first-of-their-kind observations in the human brain, an international team of researchers has revealed two well-known neurochemicals -- dopamine and serotonin -- are at work at sub-second speeds to shape how people perceive the world and take action based on their perception.

13 Oct 2020

Researchers trace neurons in mosquitoes that sense blood's distinctive flavor

It's one of the world's deadliest animals, and it has a taste for human blood: the mosquito. Mosquitoes spread diseases like malaria, dengue, and yellow fever that kill at least a half a million people each year. Now researchers are learning what humans taste like to mosquitoes, down to the individual neurons that sense blood's distinctive, delectable flavor.

13 Oct 2020