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Researchers discover protein involved in protecting B cells

Whenever a germ gets into the human body, the immune system usually responds immediately to fight off the enemy attacker. One of our defense system's most important strategies involves B lymphocytes, also known as B cells, which produce antibodies that target and neutralize pathogens.

2 Jul 2020

Discovery of new step in brain cell mechanism could lead to new treatments for epilepsy

Researchers have identified a critical new step in how brain cells function in people with one of the most common forms of epilepsy.

2 Jul 2020

Long-term culture of human pancreatic slices as a model to study regeneration of beta cells

Scientists from the Diabetes Research Institute at the University of Miami Miller School of Medicine have developed a method allowing for the long-term culture of "pancreatic slices" to study the regeneration of the human pancreas in real time.

2 Jul 2020

Discovery provides hints at the evolution of ear and jaw bones in early mammals

Infant marsupials and monotremes use a connection between their ear and jaw bones shortly after birth to enable them to drink their mothers' milk, new findings in eLife reveal.

1 Jul 2020

Study can help develop targeted drugs for cancer and other diseases

In the field of molecular biology, chaperones are a group of proteins that help regulate protein folding. Folding is a significant step in protein synthesis.

1 Jul 2020

In vitro cardiotoxicity screening using 3D-printed human heart tissues

Ramot at Tel Aviv University has signed a collaboration agreement with Bayer to develop and validate a platform for in vitro cardiotoxicity screening, using human heart tissues 3D-printed in Prof. Tal Dvir's Laboratory for Tissue Engineering and Regenerative Medicine at Tel Aviv University.

1 Jul 2020

Study provides roadmap for developing effective vaccine against Staphylococcal infections

Experiments in mice have shown early success in vaccinating them against potentially deadly bacterial infections, such as methicillin-resistant Staphylococcal aureus, or MRSA, the strain resistant to most drug treatments.

1 Jul 2020

Lab-grown 'mini-brains' can be infected by SARS-CoV-2 virus

A multidisciplinary team from two Johns Hopkins University institutions, including neurotoxicologists and virologists from the Bloomberg School of Public Health and infectious disease specialists from the school of medicine, has found that organoids (tiny tissue cultures made from human cells that simulate whole organs) known as "mini-brains" can be infected by the SARS-CoV-2 virus that causes COVID-19.

1 Jul 2020

COVID-19 virus can infect heart cells in a lab dish, study shows

A new study shows that SARS-CoV-2, the virus that causes COVID-19 (coronavirus), can infect heart cells in a lab dish, indicating it may be possible for heart cells in COVID-19 patients to be directly infected by the virus.

1 Jul 2020

Chiral ligands can help develop novel drugs and bioactive compounds

Numerous therapeutic compounds—such as amino acids, enzymes, and proteins— that are currently available in the market are “chiral compounds.”

1 Jul 2020

Genome sequencing reveals signposts in DNA for cancer, disease risk

By sequencing entire genomes for DNA modifications, and analyzing both cancer tissues and healthy ones, Hackensack Meridian Health researchers and doctors have found what could be a key to risks for cancer and other diseases: specific locations in the DNA where those expression changes (methylation) are imbalanced, according to a new publication.

30 Jun 2020

Antibiotic resistance genes persist in E. coli through 'genetic capitalism', study shows

We have known for some time that over-use of antibiotics is causing a frightening increase in antibiotic resistance in bacteria, through the rapid spread of antibiotic resistance genes.

29 Jun 2020

Researchers identify osmotic stress as stimulator of cellular waste disposal

Cellular waste disposal, where autophagy and lysosomes interact, performs elementary functions, such as degrading damaged protein molecules, which impair cellular function, and reintroducing the resulting building blocks such as amino acids into the metabolic system.

29 Jun 2020