Proteomics News and Research

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The term 'proteome' was first coined in 1994, and refers to all the proteins in a cell, tissue, or organism. Proteomics refers to the study of the proteome. Because proteins are involved in almost all biological activities, the proteome is a rich source of biological information.

UTEP researchers discover new target for tuberculosis drug development

Biology students and faculty members from The University of Texas at El Paso have discovered a new target for tuberculosis drug development.

1 Jul 2020

Subtypes in alzheimer's disease may be linked to tau protein modifications

A new study reveals a possible biological reason that Alzheimer's Disease (AD) progresses at different rates in different patients.

25 Jun 2020

Mouse models help understand the functioning of muscles

The quest to detect all kinds of proteins that constitute the sarcomere, the fundamental contractile unit of muscle cells, led to a surprising revelation.

22 Jun 2020

Fantastic Muscle Proteins And Where To Find Them

Researchers at MDC developed a mouse model that enables them to look inside a working muscle and identify the proteins that allow the sarcomere to contract.

22 Jun 2020

Researchers unlock a weakness in common type of cancer cells

Like any cells in the body, cancer cells need sugar - namely glucose - to fuel cell proliferation and growth. Cancer cells in particular metabolize glucose at a much higher rate than normal cells.

19 Jun 2020

Structural map reveals changes in SMCHD1 protein linked to degenerative conditions

Researchers have used structural biology to map a portion of a protein called SMCHD1, describing how certain modifications can lead to degenerative conditions.

18 Jun 2020

NJIT researchers develop new efficient method to quantify therapeutic proteins

Researchers at New Jersey Institute of Technology in collaboration with Ohio University and Merck & Co. Inc. recently developed a new efficient method for targeted protein analysis -- one they say could speed up processes for disease testing, drug discovery and vaccine development.

18 Jun 2020

Solving A Parkinson's Disease Puzzle Through Protein Design

Dopamine is a neurotransmitter involved in everything and the receptors have been a longstanding target for treating disorders like Parkinson's disease.

17 Jun 2020

Protein glycosylation plays a major role in DNA methylation

An underlying principle in molecular biology is that “DNA makes RNA makes protein.” The process of gene expression is firmly controlled in various ways.

12 Jun 2020

Intron detention is integral to post-transcriptional regulation mechanism

Muscle stem cells are the reserve stem cells found in skeletal muscles. They play a crucial role in muscle repair following damage.

11 Jun 2020

Stress-induced chemoresistance is linked to changes in cellular metabolism

There is a wide range of mechanisms related to chemoresistance, a majority of which are yet to be fully understood.

11 Jun 2020

Protein dynamics can help fight bacterial infections

When pathogenic bacteria infect, the body’s immune system attempts to remove these invaders. One method to do this is to trigger an inflammatory response.

10 Jun 2020

Study reveals the role of Cpeb4 protein involved in bone and joint diseases

Osteoclasts are bone-dissolving cells that are extracted from a type of immune cell referred to as macrophages which are required for the maintenance of bones.

10 Jun 2020

Study reveals new insight on vaccines and antimicrobials

Bacteria are known to be versatile living organisms capable of colonizing a wide variety of tissues, hosts, or environments inside a host.

9 Jun 2020

New model decodes relationship between metabolic mechanisms and genes

New research introduces a unique mathematical method to study human metabolism by decreasing the complexities of the human genome-scale GEMs.

5 Jun 2020

Making opioids safer and more effective

Dr. John Streicher speaks to AZoLifeSciences about his research on improving opioid drugs to make them safer and more effective.

From University of Arizona 28 May 2020

Biochemical and computational methods for large-scale protein-arginine methylation analysis

Methylation (namely addition of a methyl group) of arginine amino acid residues of proteins is a post-translational modification (PTM) catalyzed by a family of nine enzymes called Protein Arginine Methyl-Transferases (PRMTs).

23 May 2020

New Functions Of A Protein May Improve Biocontrol Methods In Sustainable Agriculture

The laboratory of the UMA has proved that Bacillus subtilis cells, when deprived of an amyloid protein (TasA), exhibit a range of cytological anomalies.

19 May 2020

Smokers More Likely To Express ACE2 Protein That SARS-COV-2 Uses

Researchers report that smoking increases the gene expression of ACE2, the protein that binds SARS-CoV-2, which may promote COVID-19 infection.

19 May 2020

Computational methods can help design protein-based vaccines

Vaccines are regarded as an effective intervention to stop the spread of infectious diseases. They produce antibodies by activating the immune system.

18 May 2020