Proteomics News and Research

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The term 'proteome' was first coined in 1994, and refers to all the proteins in a cell, tissue, or organism. Proteomics refers to the study of the proteome. Because proteins are involved in almost all biological activities, the proteome is a rich source of biological information.

Solving A Parkinson's Disease Puzzle Through Protein Design

Dopamine is a neurotransmitter involved in everything and the receptors have been a longstanding target for treating disorders like Parkinson's disease.

17 Jun 2020

Protein glycosylation plays a major role in DNA methylation

An underlying principle in molecular biology is that “DNA makes RNA makes protein.” The process of gene expression is firmly controlled in various ways.

12 Jun 2020

Intron detention is integral to post-transcriptional regulation mechanism

Muscle stem cells are the reserve stem cells found in skeletal muscles. They play a crucial role in muscle repair following damage.

11 Jun 2020

Stress-induced chemoresistance is linked to changes in cellular metabolism

There is a wide range of mechanisms related to chemoresistance, a majority of which are yet to be fully understood.

11 Jun 2020

Protein dynamics can help fight bacterial infections

When pathogenic bacteria infect, the body’s immune system attempts to remove these invaders. One method to do this is to trigger an inflammatory response.

10 Jun 2020

Study reveals the role of Cpeb4 protein involved in bone and joint diseases

Osteoclasts are bone-dissolving cells that are extracted from a type of immune cell referred to as macrophages which are required for the maintenance of bones.

10 Jun 2020

Study reveals new insight on vaccines and antimicrobials

Bacteria are known to be versatile living organisms capable of colonizing a wide variety of tissues, hosts, or environments inside a host.

9 Jun 2020

New model decodes relationship between metabolic mechanisms and genes

New research introduces a unique mathematical method to study human metabolism by decreasing the complexities of the human genome-scale GEMs.

5 Jun 2020

Making opioids safer and more effective

Dr. John Streicher speaks to AZoLifeSciences about his research on improving opioid drugs to make them safer and more effective.

From University of Arizona 28 May 2020

Biochemical and computational methods for large-scale protein-arginine methylation analysis

Methylation (namely addition of a methyl group) of arginine amino acid residues of proteins is a post-translational modification (PTM) catalyzed by a family of nine enzymes called Protein Arginine Methyl-Transferases (PRMTs).

23 May 2020

New Functions Of A Protein May Improve Biocontrol Methods In Sustainable Agriculture

The laboratory of the UMA has proved that Bacillus subtilis cells, when deprived of an amyloid protein (TasA), exhibit a range of cytological anomalies.

19 May 2020

Smokers More Likely To Express ACE2 Protein That SARS-COV-2 Uses

Researchers report that smoking increases the gene expression of ACE2, the protein that binds SARS-CoV-2, which may promote COVID-19 infection.

19 May 2020

Computational methods can help design protein-based vaccines

Vaccines are regarded as an effective intervention to stop the spread of infectious diseases. They produce antibodies by activating the immune system.

18 May 2020

Study shows the dual role of amyloid proteins in Bacillus physiology

When Bacillus subtilis cells are deprived of an amyloid protein, they show a range of cytological dysfunctions and anomalies that cause their premature death.

18 May 2020

Discovering a Protein that Controls Brain-Blood Vessel Development

AZoLifeSciences speaks to Professor Long Nam Nguyen about his research which led to the discovery of a protein that controls brain-blood vessel development.

From National University of Singapore (NUS) 15 May 2020

Researchers identify missing component of innate immune signaling

How cells recognize pathogens and alert the immune system swiftly is a fundamental process of high importance for the survival of any species, including humans.

14 May 2020

Study shows how plant viral protein disrupts cell division to promote its own propagation

Viruses are ever-present pathogens that lead to severe infectious diseases in humans as well as in agricultural crops.

14 May 2020

Study shows protein shredder also regulates fat metabolism indirectly

A protein shredder takes place in the cell membranes of brain cells. A new study has demonstrated that this protein shredder also controls fat metabolism.

11 May 2020

MSC‐induced Treg population can yield abundant replacement for naturally occurring T-cells

A new study released today in STEM CELLS suggests for the first time that regulatory T-cells (Treg) induced by mesenchymal stromal cells can yield an abundant replacement for naturally occurring T-cells, which are vital in protecting the body from infection.

30 Apr 2020