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Bacteria Have Complex Circadian Clocks, Study Finds

Bacteria make up more than 10% of all living things but until recently we had little realization that, as in humans, soil bacteria have internal clocks that synchronize their activities with the 24-hour cycles of day and night on Earth.

7 Aug 2023

Leveraging Nature's Blueprint: The Impact of Directed Evolution in Protein Engineering

In this interview conducted at SLAS EU 2023 in Brussels, Belgium, we spoke to Miguel Alcalde, a Research Professor at the CSIC, about directed evolution in enzymology and the wider biotechnology sector.

From Society for Laboratory Automation and Screening (SLAS) 4 Aug 2023

Gut Hormone Plays a Vital Role in Maintaining the Balance of Fungi in the Digestive System of Mammals

Peptide YY (PYY), a hormone produced by gut endocrine cells that was already known to control appetite, also plays an important role in maintaining the balance of fungi in the digestive system of mammals, according to new research from the University of Chicago.

4 Aug 2023

Amazon Dark Earth for Accelerated Tree Growth

A study published in the journal Frontiers in Soil Science asserts that a type of soil known as terra preta da Amazônia, or Amazon dark earth (ADE), encourages quicker growth of trees and improves their development in terms of quality.

2 Aug 2023

Researchers Develop New Photoenzymatic Method to Produce Chiral Amines

Using energy from light to activate natural enzymes can help scientists create new-to-nature enzymatic reactions that support eco-friendly biomanufacturing -; the production of fuels, plastics, and valuable chemicals from plants or other biological systems.

1 Aug 2023

New Gene Editing Technique Reduces Chalkiness in Rice

As global temperatures continue to rise, maintaining the quality and yield of crops adapted to lower temperatures will increasingly become a challenge.

31 Jul 2023

Analyzing DNA Damage-Induced NF-κB Targeted by Novel Small Molecule Inhibitors

Chemotherapy and radiotherapy aim to destroy cancer cells by inducing DNA double-strand breaks – damage that, once inflicted, usually causes the cells to die. But damage to a cell's genetic material also activates a signaling pathway called IKK/NF-κB that helps prevent cell death, thus limiting the success of these treatments in patients.

28 Jul 2023

Towards Artificial Photosynthesis with Engineering of Protein Crystals in Bacteria

In-cell engineering can be a powerful tool for synthesizing functional protein crystals with promising catalytic properties, show researchers at Tokyo Tech.

26 Jul 2023

In-Cell Engineering Proves to be a Powerful Tool for Synthesizing Functional Protein Crystals

In-cell engineering can be a powerful tool for synthesizing functional protein crystals with promising catalytic properties, show researchers at Tokyo Tech.

26 Jul 2023

Essential Bacterial Signaling Autoproteolysis in C. thermocellum

Sensing and communicating with the extracellular environment are both aspects of transmembrane signaling.

24 Jul 2023

New Process by Which Enzymes Help Prevent Heart Damage in Chemotherapy Patients Identified

Researchers at the University of Illinois Chicago have identified a process by which enzymes can help prevent heart damage in chemotherapy patients.

21 Jul 2023

Scientists Identify Key Regulator of Bacterial Cell Wall Remodeling

The bacterial cell wall must be constantly remodeled in order to grow and divide. This involves the close coordination of lytic enzymes and peptidoglycan synthesis.

20 Jul 2023

Rensselaer Professor Receives $400,000 Grant to Study Deep Sea Enzymes

Rensselaer Polytechnic Institute's Catherine Royer, Constellation Chair Professor of Bioinformatics and Biocomputation at the Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS) and professor of biological sciences, has received a grant of over $400,000 from the National Science Foundation to investigate enzymes from organisms living in deep sea environments.

14 Jul 2023

Researchers Uncover Astonishing Diversity of Protein Structures Previously Unexplored

The astounding variety of protein structures and their folds in nature has been further illuminated by a ground-breaking discovery. Researchers wanted to know how much of the huge range of potential protein structures nature had examined.

12 Jul 2023

Scientists Develop Method to Create Artificial Allosteric Sites in Protein Complexes

According to a recently published research paper by a team of scientists, a groundbreaking approach has been developed to create artificial allosteric sites (where by binding an effector molecule, activity at the distal active site is regulated) in protein complexes.

7 Jul 2023

New Method Reveals How Hepatitis C Virus Evades Immune System

With a new method for examining virus samples researchers from the University of Copenhagen have solved an old riddle about how Hepatitis C virus avoids the human body's immune defenses.

6 Jul 2023

Glutaminase 2 Plays a Key Role in Glucose Homeostasis

Glutaminase 2 (GLS2) is a master regulator of glutaminolysis. GLS2 converts glutamine to glutamate, thereby playing a role in cellular energy production. GLS2 is abundant in the liver, and is also found in pancreatic β-cells. However, the role of GLS2 in pancreatic islets – in which both ɑ- and β- cells are present – associated with glucose metabolism is currently unknown.

6 Jul 2023

Deep Learning Model Accurately Predicts RNA-Targeting CRISPR Activity

According to new research published in Nature Biotechnology, artificial intelligence can predict on- and off-target behavior of CRISPR tools that target RNA rather than DNA.

5 Jul 2023

Genetically Modified iPS Cell Applications for Fabry Disease

iPS cells have had a significant impact on biology and medicine, and they are expected to increase regenerative medicine. Clinical trials with various cell types derived from iPS cells have been performed since 2014 when a sheet of retinal pigment epithelial cells obtained from iPS cells was transplanted into patients with age-related macular degeneration.

4 Jul 2023

Camena Bioscience Closes $10m Series A Financing as Demand for DNA Synthesis Technology Increases

Camena Bioscience, a synthetic biology company providing genes to the pharmaceutical and biotechnology industries, today announced it has closed a $10m Series A financing round, led by Mercia.