Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

BU researchers develop new way to better understand human cell communication

Researchers from Boston University School of Medicine have developed and implemented a new way to better understand how human cells communicate with each other, how this communication is disrupted in human diseases and how this can be corrected pharmacologically.

7 Jul 2020

Sanford Burnham Prebys announces research agreement with Lilly to characterize COVID-19 antibodies

Sanford Burnham Prebys Medical Discovery Institute today announced a research agreement with Eli Lilly and Company (Lilly) to characterize Lilly's next-generation anti-SARS-CoV-2 antibodies.

30 Jun 2020

Existing drugs could disrupt SARS-CoV-2 from hijacking cells

An international team of researchers has analyzed how SARS-CoV-2, the virus that causes COVID-19, hijacks the proteins in its target cells.

30 Jun 2020

Study may help design effective treatments for Alzheimer’s disease

Neurons in the brains of such people are being depleted gradually and inevitably, resulting in the characteristic loss of cognitive function and memory.

29 Jun 2020

University of Kentucky collaborates with Atomwise to explore potential COVID-19 therapies

The University of Kentucky announced a research collaboration with Atomwise, an industry leader in using artificial intelligence (AI) for small molecule discovery, to explore potential COVID-19 therapies.

24 Jun 2020

Novel precision medicine targets cancer's DNA defenses

A new precision medicine targeting cancer's ability to repair its DNA has shown promising results in the first clinical trial of the drug class.

23 Jun 2020

NJIT researchers develop new efficient method to quantify therapeutic proteins

Researchers at New Jersey Institute of Technology in collaboration with Ohio University and Merck & Co. Inc. recently developed a new efficient method for targeted protein analysis -- one they say could speed up processes for disease testing, drug discovery and vaccine development.

18 Jun 2020

Solving A Parkinson's Disease Puzzle Through Protein Design

Dopamine is a neurotransmitter involved in everything and the receptors have been a longstanding target for treating disorders like Parkinson's disease.

17 Jun 2020

New protein design could help in drug discovery for Parkinson’s disease

The neurotransmitter dopamine plays a vital role in everything, starting from motor control to higher cognitive functions, arousal, motivation, sexual gratification, and reinforcement.

12 Jun 2020

'Fat burning' molecule holds promise for future treatment and prevention of obesity

Obesity affects more than 40 percent of adults in the United States and 13 percent of the global population.

9 Jun 2020

Teixobactin-based drug can kill superbugs

A team of researchers has reached one step closer in its quest for developing a feasible teixobactin-based drug.

8 Jun 2020

UCL scientists discover genes responsible for maintaining healthy hearing

Scientists at UCL have discovered sets of regulatory genes, which are responsible for maintaining healthy hearing. The finding, made in fruit flies, could potentially lead to treatments for age-related hearing loss (ARHL) in humans.

From University College London 3 Jun 2020

Research project launched to find new treatments for rare genetic diseases

The University Carlos III Madrid, Almirall, S.A. and the MEDINA Foundation have launched a project to find new treatments for recessive dystrophic epidermolysis bullosa and other genetic diseases caused by nonsense mutations.

29 May 2020

Innovative tool to speed up the drug discovery process

A better understanding of the interaction between a molecule and the organism is important to consider its therapeutic potential.

21 May 2020

X-ray experiments reveal antibody to block entry of SARS-CoV-2

As scientists across the globe race to develop a vaccine against SARS-CoV-2, the coronavirus that causes COVID-19, an international team led by Davide Corti at Vir Biotechnology and David Veesler at the University of Washington has been working around the clock on a complementary approach - identifying neutralizing antibodies that could be used as a preventative treatment or as a post-exposure therapy.

20 May 2020