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Researchers use body-on-a-chip cancer models to study personalized immunotherapy response

Wake Forest researchers and clinicians are using patient-specific tumor 'organoid' models as a preclinical companion platform to better evaluate immunotherapy treatment for appendiceal cancer, one of the rarest cancers affecting only 1 in 100,000 people.

20 Jul 2021

Metabolite produced by gut microbes found to be involved in regulating commensal bacteria

Researchers at the RIKEN Center for Integrative Medical Sciences (IMS) have discovered that acetate, a major metabolite produced by some intestinal bacteria, is involved in regulating other intestinal bacteria.

20 Jul 2021

Gene therapy may be safe and effective in treating AADC deficiency

A new study published in Nature Communications suggests that gene therapy delivered into the brain may be safe and effective in treating aromatic L-amino acid decarboxylase (AADC) deficiency.

19 Jul 2021

New multimodal diagnostic can detect cancer cells and pinpoint tumor location

Most of the tests that doctors use to diagnose cancer -- such as mammography, colonoscopy, and CT scans -- are based on imaging. More recently, researchers have also developed molecular diagnostics that can detect specific cancer-associated molecules that circulate in bodily fluids like blood or urine.

19 Jul 2021

Study confirms long-term immune system responses of adenovirus vaccines for COVID-19

Researchers from the University of Oxford suggest that adenovirus vaccine vectors may create strong long-term immune system responses.

19 Jul 2021

Study reveals the basis of oxygenation fluctuations in brain

The brain is supplied with sufficient nutrients and oxygen due to the blood flow; however, the oxygenation is likely to fluctuate distinctly and uniformly.

From Penn State University 19 Jul 2021

Study shows how to unlock CRISPR’s potential to regulate many genes simultaneously

A new technique to regulate several genes in engineered yeast cells could pave the way for the highly efficient, sustainable production of bio-based products.

19 Jul 2021

Specific subset of fibroblast cells could provide protection from debilitating lung disease

Single-cell RNA sequencing has revealed a subset of cells that could provide protection from a rare, but severely debilitating and fatal, lung disease.

16 Jul 2021

Cells damaged by chronic lung disease favor SARS-CoV-2 entry

Researchers propose that similar to pouring water atop a wellhead prior to pumping, the airway cells of patients suffering from chronic lung diseases are “primed” for infection by the COVID-19 virus.

16 Jul 2021

Study discloses neuroprotective properties of aromatic turmerone and its derivatives

Scientists discovered that aromatic turmerone and its derivatives have a direct effect on the dopaminergic nerves.

16 Jul 2021

Insights on double-strand break repair may provide better understanding of cancer development

The BRCA1 protein known widely for its role in hereditary breast cancer is also a vital part of the cellular system repairing double-stranded DNA breaks.

From Osaka University 16 Jul 2021

Study reveals neurotransmitter releases impairments in schizophrenia patients

A research team revealed that neurotransmitter release in the brain is impaired in patients with schizophrenia who possess a rare, single-gene mutation.

16 Jul 2021

Brainless slime mold uses its body to sense mechanical cues in the environment

If you didn't have a brain, could you still figure out where you were and navigate your surroundings? Thanks to new research on slime molds, the answer may be "yes."

15 Jul 2021

AMSBIO launches new range of biosimilar antibodies for research use

AMSBIO has launched a new range of research grade biosimilars that enable analysis of biological processes without the need to purchase expensive therapeutic-grade biologics.

From AMS Biotechnology 15 Jul 2021

Synthesis of complete crenarchaeol molecule elucidates its structure

Crenarchaeol is a large, closed-loop lipid that is present in the membranes of ammonium-oxidizing archaea, a unicellular life form that exists ubiquitously in the oceans.

14 Jul 2021

Mass spectrometry: Important analytical tool to understand Huntington’s disease proteome

Mass spectrometry has emerged as an important analytical tool for gaining a better understanding of mechanisms underlying Huntington's disease (HD), alongside the increased availability of cell and animal models of the disease.

14 Jul 2021

Novel gene therapy offers hope to children with genetic, neurodegenerative diseases

Newly devised gene therapy can help children born with AADC, a rare genetic disorder that causes developmental and physical disabilities.

13 Jul 2021

Researchers establish efficient genetic engineering platform in Pichia pastoris

Pichia pastoris is a model methylotrophic yeast that can easily realize high-density fermentation.

13 Jul 2021

Optogenetic control of stomatal guard cells could help prevent transpiration in plants

Stomata, the small microscopic pores present on leaves in plants, aids in regulating the influx of carbon dioxide for photosynthesis.

13 Jul 2021

Researchers identify a novel pathomechanism leading to Usher syndrome

Human Usher syndrome (USH) is the most common form of hereditary deaf-blindness. Sufferers can be deaf from birth, suffer from balance disorders, and eventually lose their eyesight as the disease progresses.

12 Jul 2021

Cell News and Research

Researchers use body-on-a-chip cancer models to study personalized immunotherapy response

Metabolite produced by gut microbes found to be involved in regulating commensal bacteria

Gene therapy may be safe and effective in treating AADC deficiency

New multimodal diagnostic can detect cancer cells and pinpoint tumor location

Study confirms long-term immune system responses of adenovirus vaccines for COVID-19

Study reveals the basis of oxygenation fluctuations in brain

Study shows how to unlock CRISPR’s potential to regulate many genes simultaneously

Specific subset of fibroblast cells could provide protection from debilitating lung disease

Cells damaged by chronic lung disease favor SARS-CoV-2 entry

Study discloses neuroprotective properties of aromatic turmerone and its derivatives

Insights on double-strand break repair may provide better understanding of cancer development

Study reveals neurotransmitter releases impairments in schizophrenia patients

Brainless slime mold uses its body to sense mechanical cues in the environment

AMSBIO launches new range of biosimilar antibodies for research use

Synthesis of complete crenarchaeol molecule elucidates its structure

Mass spectrometry: Important analytical tool to understand Huntington’s disease proteome

Novel gene therapy offers hope to children with genetic, neurodegenerative diseases

Researchers establish efficient genetic engineering platform in Pichia pastoris

Optogenetic control of stomatal guard cells could help prevent transpiration in plants

Researchers identify a novel pathomechanism leading to Usher syndrome

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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