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New MRSA superbug tactic could boost vaccine development

A new study has discovered a novel tactic used by the bacterium Staphylococcus aureus to resist the immune response, boosting hopes that a vaccine to prevent lethal MRSA infections is closer than previously thought.

25 Jun 2021

Scientists decode humans’ adaptations to historical coronavirus outbreaks

An international research team, jointly headed by the University of Adelaide and the University of Arizona, has examined the genomes of over 2,500 modern humans from 26 global populations to gain a better understanding of people’s adaptations to the historical outbreaks of coronavirus.

25 Jun 2021

New 3Cs multiplex approach enables the study of the effect of genetic changes

Dr Manual Kaulich’s team at Goethe University has developed a new 3Cs multiplex approach that permits the effect of genetic alterations in any two genes to be investigated simultaneously in cell cultures.

25 Jun 2021

Researchers identify key cells involved in childhood brain cancer

A new study coordinated by the University of Trento could have identified the cell of origin of medulloblastoma—a malignant tumor in children that affects the central nervous system. In this study, scientists have used organoids to replicate the tumor tissue, for the first time.

25 Jun 2021

Study may help develop multi-pronged HIV eradication strategies

A team of researchers from the University of California - Davis Health (UC Davis) has made a breakthrough discovery of a unique type of stem cell that reduces the amount of the virus that causes AIDS.

From The University of California, Davis 25 Jun 2021

New methodology assesses whole-genome sequencing data of SARS-CoV-2 mutations

According to researchers from Harvard T.H. Chan School of Public Health and MIT, the use of genome-wide association studies (GWAS) methodology to assess whole-genome sequencing data of SARS-CoV-2 mutations and COVID-19 mortality data can help identify highly pathogenic variants of the virus that should be flagged for containment.

25 Jun 2021

Prevalent protein in the blood plays a vital role in human fertilization, infection resistance

Albumin activates a proton channel which allows sperm to penetrate and fertilize an egg and white blood cells to secrete large amounts of inflammatory mediators.

23 Jun 2021

New device can examine and separate single cells based on their response to stimuli

A novel technology that can inspect and separate single cells based on their response to stimuli could help develop personalized treatment.

From University of Exeter 23 Jun 2021

New nanobodies could fight against SARS-CoV-2 variants

Looking for a new strategy in the long-running battle against the SARS-CoV-2 virus, researchers have developed nanobodies.

23 Jun 2021

Researchers create first plant embryo gene expression atlas at the single-cell level

A team of researchers from the GMI has created the first plant embryo gene expression atlas at the single-cell level.

22 Jun 2021

New airway model boosts COVID-19 research

A research team has successfully built a model of lung cells that can be used to simulate how COVID-19 infects the airways.

22 Jun 2021

Fluorescence microscopy and deep learning predict viral infections

Researchers have now used fluorescence images from live cells to train an artificial neural network to reliably detect cells that are infected by herpes viruses.

22 Jun 2021

Study sheds new light on age-related diseases

Researchers from Sanford Burnham Prebys have explored the intricacies of autophagy to get a better understanding of the process.

21 Jun 2021

Protein known to mediate cell death plays a key role in maturation and release of interleukin-1α

Interluekin-1α (IL-1α) is an important part of the immune response, but until now it has been unclear how this molecule is processed from its precursor, pro-IL-1α, and exits the cell during inflammasome activation.

21 Jun 2021

Study reveals how cells “read” synthetic ingredients added to a genetic code

If the genome is considered the recipe for life, then base pairs represent the individual ingredients. DNA is made up of these chemical structures, and every living thing on the planet has just four of them.

21 Jun 2021

New method to control the complex communication network of cells

A study has proposed a new method for developing novel drugs based on the suppression of tyrosine kinase enzymes.

21 Jun 2021

A new treatment approach against SARS-CoV-2

Scientists have come up with a new method to treat SARS-CoV-2 infection by fixing the cell damage instead of fighting the virus directly.

21 Jun 2021

Inhibition of necroptosis may be a new therapeutic approach to treating COPD

Research shows that inhibiting necroptosis, a form of cell death, could be a novel therapeutic approach for treating chronic obstructive pulmonary disease (COPD), an inflammatory lung condition, also known as emphysema, that makes it difficult to breathe.

21 Jun 2021

Genetically engineering NK cells can target and kill glioblastoma stem cells

Preclinical research from The University of Texas MD Anderson Cancer Center finds that although glioblastoma stem cells (GSCs) can be targeted by natural killer (NK) cells, they are able to evade immune attack by releasing the TFG-β signaling protein, which blocks NK cell activity.

18 Jun 2021

Presence of certain stem cells correlates with non-genetic resistance mechanisms to cancer drugs

Cancer cells can develop resistance to therapy through both genetic and non-genetic mechanisms. But it is unclear how and why one of these routes to resistance prevails.

18 Jun 2021