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New computer algorithm helps identify tumors with 'mismatch repair deficiencies'

A new way to identify tumors that could be sensitive to particular immunotherapies has been developed using data from thousands of NHS cancer patient samples sequenced through the 100,000 Genomes Project.

27 Apr 2021

Cell adaptation to adverse conditions could differentiate survivors and non-survivors of critical illness

Creating the best conditions for cells to make energy and survive critical illness is a challenge little understood in modern medicine.

27 Apr 2021

SDIR1 enzyme plays a major role in the expression of defense gene in plants

A new study offers evidence that microbes are trying to hijack the plant immune system to induce disease while also offering insights into a new mechanism.

26 Apr 2021

New tool enables non-experts to interpret microscopy images using AI

A new, open-source tool enables non-experts to interpret microscopy images using artificial intelligence.

26 Apr 2021

Therapy using artificial metalloenzymes helps reduce tumor growth, finds study

A new study has shown that it is viable to reduce tumor growth by a therapy that involves tagging cancer cells with various therapeutic molecules.

26 Apr 2021

Cell membranes can boost the production of protein-based vaccines

Synthetic biologists have cracked open a cellular membrane, identifying a new method to boost the production yields of protein-based vaccines by five times.

26 Apr 2021

New AI model predicts targets for previously unmapped T cells against coronavirus

A research team has created an AI technique that can bind immune cells to their targets and uncouple the types of white blood cells that identify SARS-CoV-2.

26 Apr 2021

Small molecular changes can have dramatic impact on the CAR T cell function

When researchers from Penn Medicine found that many patients with B-cell acute lymphoblastic leukemia (ALL) treated with the investigational chimeric antigen receptor (CAR) T cell therapy targeting the CD22 antigen didn't respond, they went back to the drawing board to determine why.

23 Apr 2021

National DNA Day 2021: An Interview with Professor George Church

In celebration of National DNA Day, AZoLifeSciences interviews renowned DNA expert Professor George Church about his life-long career in DNA research.

From Harvard Medical School 23 Apr 2021

SARS-CoV-2 infection produces antibodies that can destroy infected cells

Research teams investigated the antibodies generated in people with symptomatic or asymptomatic SARS-CoV-2 infection.

From Institut Pasteur 23 Apr 2021

Study identifies mechanism that enables SARS viruses to efficiently replicate in infected cells

Researchers have now identified how SARS viruses improve the production of viral proteins in infected cells such that new copies of the virus can be produced.

23 Apr 2021

New gene editing approach bypasses disease-causing mutations

A new approach to gene editing using the CRISPR/Cas9 system bypasses disease-causing mutations in a gene, enabling treatment of genetic diseases linked to a single gene, such as cystic fibrosis, certain types of sickle cell anemia, and other rare diseases.

From Penn State University 22 Apr 2021

New algorithm maps gene expression patterns into specific locations

Cell-type databases are increasing in size and complexity as researchers accumulate a great deal of gene-sequencing data.

21 Apr 2021

Study reveals key lipid-binding protein that contributes to cancer

Researchers have discovered how a portion of a protein communicates with a cell’s membrane to control crucial intercellular communications.

21 Apr 2021

Study offers new ways to think about the immune system

Scientists have discovered new methods to interpret the immune system, as part of a new study reported in the Nature journal.

21 Apr 2021

Study finds raised levels of specific immune cells in asymptomatic people with COVID-19

The largest study of its type in the UK has identified differences in the immune response to COVID-19, between people with no symptoms, compared to those suffering a more serious reaction to the virus.

21 Apr 2021

Chaperone protein imbalance initiates toxic accumulation of tau in the aging brain

Chaperone protein imbalance can play a significant role in initiating toxic accumulation of tau in the aging brain - an early step in the development of Alzheimer's disease and related neurodegenerative disorders known as tauopathies, a new preclinical study by University of South Florida Health (USF Health) neuroscientists suggests.

21 Apr 2021

Researchers uncover a key genetic culprit in the development of acute lymphoblastic leukemia

Using a widely known field of mathematics designed mainly to study how digital and other forms of information are measured, stored and shared, scientists at Johns Hopkins Medicine and Johns Hopkins Kimmel Cancer Center say they have uncovered a likely key genetic culprit in the development of acute lymphoblastic leukemia (ALL).

21 Apr 2021

Study highlights the importance of autophagy in gene regulation

A fine balance between the production and degradation of biomolecules is required for optimal cell function. Autophagy is a mechanism through which cells break down and recycle their own components.

20 Apr 2021

Key discovery could prevent treatment failure in people with severe hemophilia A

Recently, researchers achieved a crucial discovery that could mitigate and eliminate immune responses causing treatment failure in people with hemophilia A.

20 Apr 2021

Cell News and Research

New computer algorithm helps identify tumors with 'mismatch repair deficiencies'

Cell adaptation to adverse conditions could differentiate survivors and non-survivors of critical illness

SDIR1 enzyme plays a major role in the expression of defense gene in plants

New tool enables non-experts to interpret microscopy images using AI

Therapy using artificial metalloenzymes helps reduce tumor growth, finds study

Cell membranes can boost the production of protein-based vaccines

New AI model predicts targets for previously unmapped T cells against coronavirus

Small molecular changes can have dramatic impact on the CAR T cell function

National DNA Day 2021: An Interview with Professor George Church

SARS-CoV-2 infection produces antibodies that can destroy infected cells

Study identifies mechanism that enables SARS viruses to efficiently replicate in infected cells

New gene editing approach bypasses disease-causing mutations

New algorithm maps gene expression patterns into specific locations

Study reveals key lipid-binding protein that contributes to cancer

Study offers new ways to think about the immune system

Study finds raised levels of specific immune cells in asymptomatic people with COVID-19

Chaperone protein imbalance initiates toxic accumulation of tau in the aging brain

Researchers uncover a key genetic culprit in the development of acute lymphoblastic leukemia

Study highlights the importance of autophagy in gene regulation

Key discovery could prevent treatment failure in people with severe hemophilia A

Driving Support for Pharmaceutical Testing Through Continuous Innovation

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