Anemia News and Research

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Anemia is a decrease in normal number of red blood cells (RBCs) or less than the normal quantity of hemoglobin in the blood. However, it can include decreased oxygen-binding ability of each hemoglobin molecule due to deformity or lack in numerical development as in some other types of hemoglobin deficiency. The three main classes of anemia include excessive blood loss (acutely such as a hemorrhage or chronically through low-volume loss), excessive blood cell destruction (hemolysis) or deficient red blood cell production (ineffective hematopoiesis). Anemia is the most common disorder of the blood. There are several kinds of anemia, produced by a variety of underlying causes. Anemia can be classified in a variety of ways, based on the morphology of RBCs, underlying etiologic mechanisms, and discernible clinical spectra, to mention a few.

Experimental optimization of prime editing to achieve high efficiency

Genome editing technologies have enormous potential for treating genetic diseases. Techniques like the extensively used CRISPR/Cas9 gene scissors target the source of the disease directly in the DNA.

3 Feb 2023

Novel adoptive T cell receptor therapy shows promising results for patients with solid tumors

Afamitresgene autoleucel (afami-cel; formerly ADP-A2M4), an adoptive T cell receptor (TCR) therapy targeting the MAGE-A4 cancer antigen, achieved clinically significant results for patients with multiple solid tumor types in a Phase I clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

30 Jan 2023

Gene editing made faster than ever before using AI

The first simple production of customizable proteins known as zinc fingers to treat diseases by turning genes on and off might be enabled with the help of an artificial intelligence (AI) program.

From New York University (NYU) 27 Jan 2023

Prolonged longevity in mice with gene clusters

Numerous candidate genes that affect longevity have recently been found, according to research from the Interventions Testing Program, which is supported by the National Institute on Aging (NIA).

14 Oct 2022

Iron-sulfur cofactors are moved with the help of glutathione, experts reveal

The creation and movement of an essential class of molecules in human cells are now better understood according to a recent study.

8 Sep 2022

The complex link between pancreatic malformations and the “dark genome”

For the first time, scientists at the Centre for Genomic Regulation (CRG) have discovered a DNA sequence that is essential for pancreatic development and function.

25 Aug 2022

Researchers analyze the body’s immune cells with blood cancer cells

One in every two people will acquire cancer at some point in their lives, according to the most recent international estimate.

19 Apr 2022

Researchers develop a universal AI algorithm for deep clean-up of single cell genomic data

A single cell’s genome or transcriptome can reveal considerably more data about its place in biological systems than sequencing a full batch of cells, just as interviewing a single person about their health will provide specialized, personalized information hard to obtain from a big poll.

11 Apr 2022

Researchers determine major protein complexes that cause ribosome production

Scientists at UT Southwestern have discovered a four-protein complex that seems to play a significant function in the formation of ribosomes, which serve as protein factories for cells, as well as a surprise role in neurodevelopmental diseases.

1 Apr 2022

ISU researchers receive major funding to go forward on blood stem cells research

For years, scientists have been unable to create a patient’s blood cells to cure blood illnesses, but a recently implemented federal funding might help IOWA State University researchers take important steps toward making that prospect a reality.

21 Mar 2022

Study takes a deep dive into the molecular biology of the brain in bipolar disorder patients

In a comprehensive study involving one of the largest-ever samples of post-mortem brains, scientists at the Lieber Institute for Brain Development, in collaboration with researchers at the Johns Hopkins School of Medicine and Bloomberg School of Public Health, have pinpointed significant differences in gene expression in two specific regions of the brains of hundreds of patients who had bipolar disorder.

8 Mar 2022

Researchers find increased red blood cell destruction in astronauts

A change in the volume of red blood cells has been documented in astronauts since the earliest space missions.

7 Mar 2022

Cellular enlargement drives a decline in function of stem cells, study suggests

MIT biologists have answered an important biological question: Why do cells control their size? Cells of the same type are strikingly uniform in size, while cell size differs between different cell types. This raises the question of whether cell size is important for cellular physiology.

15 Nov 2021

Study: Sex matters when it comes to susceptibility to infections and other health conditions

A University of Alberta-led study shows that when it comes to susceptibility to infections and other health conditions, sex matters.

13 Oct 2021

Miniature CRISPR-Cas system expands applicability and implications further

For the first time, Stanford researchers have miniaturized CRISPR for mammalian gene editing, which magnifies the scope of CRISPR technology.

3 Sep 2021

Researchers develop method to preserve high-quality cultured stem cells for a long time

Hematopoietic stem cells — the precursors to blood cells — have been notoriously difficult to grow in a dish, a critical tool in basic research.

16 Aug 2021

Researchers identify gene responsible for vicine-convicine content in faba beans

Faba beans are exceptional sources of food protein; however, around 4 % of the world’s population is affected by favism.

12 Jul 2021

Study identifies the gene responsible for toxic vicine and convicine production in faba beans

Faba beans have been a good source of protein. A team of experts has now found the gene that causes the toxic vicine and convicine to be produced.

7 Jul 2021

Study shows that declining fish biodiversity can affect human nutrition

All fish are not created equal, at least when it comes to nutritional benefits. This truth has important implications for how declining fish biodiversity can affect human nutrition, according to a computer modeling study led by Cornell and Columbia University researchers.

3 Jun 2021

Study unravels a crucial element that influences gene expression in blood stem cells

A complex network of biochemical pathways keeps the living organism healthy and alive.

From National University of Singapore (NUS) 7 May 2021