Diarrhea News and Research

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Diarrhea is loose, watery stools. A person with diarrhea typically passes stool more than three times a day. People with diarrhea may pass more than a quart of stool a day. Acute diarrhea is a common problem that usually lasts 1 or 2 days and goes away on its own without special treatment. Prolonged diarrhea persisting for more than 2 days may be a sign of a more serious problem and poses the risk of dehydration. Chronic diarrhea may be a feature of a chronic disease.

Diarrhea can cause dehydration, which means the body lacks enough fluid to function properly. Dehydration is particularly dangerous in children and older people, and it must be treated promptly to avoid serious health problems.

New compound may offer a way to prevent serious C. diff infections

Each year, about 500,000 people in the U.S. deal with gastrointestinal infections from Clostridioides difficile (C. diff), and more than 20,000 die from these infections.

27 Mar 2023

The protein synthesis mechanism in the Giardia parasite

Cryo-electron microscopy was employed by Uppsala University researchers to reveal information on the protein synthesis mechanism in the parasite Giardia intestinalis, which causes diarrhea. The new findings could help in the development of specific medicines to combat Giardia and other protozoan parasites.

20 Mar 2023

Rice biologists embark on a three-year project to create genetically encoded antibiotics

Synthetic biologists at Rice University are embarking on a three-year project to create "genetically encoded antibiotics," strands of RNA that bacteria will readily copy and share that will selectively kill only disease-causing, pathogenic bacteria.

14 Mar 2023

Small group of airway neurons plays a key role in alerting the brain about infection

A new study led by researchers at Harvard Medical School illuminates how the brain becomes aware that there is an infection in the body.

9 Mar 2023

Role of probiotics and functional materials in the treatment of intestinal inflammation

Maintenance of sulfomucin is a key end point in the treatment of diarrhea and inflammatory bowel disease (IBD). However, the mechanism underlying the microbial sense to sulfomucin are poorly understood, and to date, there are no therapies targeting the secretion and maturation of sulfomucin in IBD. Considering the important role of gut microbiota in host immune regulation, maintain sulfomucin by modulating the gut microbiota is inspired.

20 Feb 2023

Blastocystis can promote or disrupt gut health, study finds

The gut microbiota contains trillions of bacteria that can promote health or cause disease under different conditions.

14 Feb 2023

Novel chemical tool reveals how bacteria adapt to the host environment

A research team guided by Professor Xiang David Li of The University of Hong Kong’s (HKU) Department of Chemistry created a new chemical tool to unveil how bacteria adjust to the host environment and control host cells.

1 Feb 2023

Genomic study helps retrace origin and spread of Shigellosis outbreak in Seattle

A genomic study of a sustained, multidrug-resistant Shigellosis outbreak in Seattle enabled scientists to retrace its origin and spread.

1 Feb 2023

New genetic condition that raises vulnerability to opportunistic infections

An international consortium co-led by Vanderbilt University Medical Center immunogeneticist Rubén Martínez-Barricarte, PhD, has discovered a new genetic disorder that causes immunodeficiency and profound susceptibility to opportunistic infections including life-threatening fungal pneumonia.

24 Jan 2023

Uncovering new function for small RNAs in Salmonella infections

Millions of people get sick from Salmonella each year because they are food-borne pathogens. These bacteria rely on a sophisticated network of genes and gene products that give them the ability to sense environmental conditions to do this.

4 Jan 2023

A new outlook on sow breeding using dietary nucleotides

The primary fetal organ systems’ growth and development are strongly influenced by the nutrition status of the mother. Late gestation is when fetal growth is rapidly accelerated, and the nutritional needs of sows rise dramatically as a result of the fetus’ rapid growth and the placenta’s quick expansion.

26 Oct 2022

Researchers utilize AI to reveal hitherto unknown 3D structures in rotavirus spike protein

The three types of rotavirus that cause gastroenteritis in individuals, known as groups A, B, and C, are the most well-known and afflict predominantly youngsters.

10 Jun 2022

Study addresses genetic diversity of Clostridioides difficile using systems biology technique

Researchers from Jacobs School of Engineering and the University of California San Diego School of Medicine collaborated with colleagues from Baylor College of Medicine to decode the genetic diversity of Clostridioides difficile, an especially dangerous pathogen in healthcare settings, using a systems biology technique.

29 Apr 2022

Diarrhea News and Research

New compound may offer a way to prevent serious C. diff infections

The protein synthesis mechanism in the Giardia parasite

Rice biologists embark on a three-year project to create genetically encoded antibiotics

Small group of airway neurons plays a key role in alerting the brain about infection

Role of probiotics and functional materials in the treatment of intestinal inflammation

Blastocystis can promote or disrupt gut health, study finds

Novel chemical tool reveals how bacteria adapt to the host environment

Genomic study helps retrace origin and spread of Shigellosis outbreak in Seattle

New genetic condition that raises vulnerability to opportunistic infections

Uncovering new function for small RNAs in Salmonella infections

A new outlook on sow breeding using dietary nucleotides

Researchers utilize AI to reveal hitherto unknown 3D structures in rotavirus spike protein

Study addresses genetic diversity of Clostridioides difficile using systems biology technique

Study shows how T cell-derived interleukin-22 promotes antibacterial defense of colonic crypts

Rockefeller scientists reveal how a narrow-spectrum antibiotic selectively targets C. diff

Plant compound may be a good therapeutic candidate for treating food allergies

New genomic study suggests protein-based antigens provide more stable vaccine targets for Shigella

A genetic variation makes sugar healthy for some Greenlanders

Tiny microbes belching toxic gas helped cause the biggest mass extinction in Earth's history

Immune cells utilize the body’s fat stores to combat infection, says study

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