Proteome News and Research

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The proteome is the entire complement of proteins expressed by a genome, cell, tissue or organism. More specifically, it is the expressed proteins at a given time point under defined conditions. The term is a blend of proteins and genome.

Unlocking the Secrets of Lipid Droplet Proteins in Arabidopsis Thaliana Leaves

Lipid droplets (LDs) serve as storage organelles found in plant leaves and seeds. While the functions of seed LD proteins in lipid metabolism are well understood, many leaf LD proteins remain unidentified.

24 Apr 2024

First Comprehensive Map of Protein Movement in Yeast Cell Cycle Revealed

An international team led by researchers at the University of Toronto has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle.

23 Apr 2024

New Study Sheds Light on Blood-Brain Barrier Dysfunction in Aging

The central nervous system requires a tightly controlled environment for the neurons in the brain to function properly and be able to process information. The blood-brain barrier, which is maintained by specific brain endothelial cells lining blood vessel inner walls, controls the exchange of chemicals between the neurological and circulatory systems.

25 Mar 2024

U of T Researchers Develop Groundbreaking Platform for Protein-Based Disease Treatment

Researchers at the University of Toronto and Sinai Health have created a new platform to identify proteins that can be co-opted to control the stability of other proteins -; a new but largely unrealized approach to the treatment of disease.

25 Mar 2024

Protein Fragments Uncover New Extremophiles, Aiding Alien Life Search

Microorganisms with perfect adaptations can survive in harsh settings, such as deep-sea tunnels and mountain peaks.

18 Mar 2024

Research Develops a Comprehensive Spatial Atlas of Proteins in the Chloroplast

Plants and algae convert solar energy into chemical energy through photosynthesis. This process is vital for life on Earth and provides us with oxygen, food, fuels, and other valuable products.

6 Oct 2023

Lipidome Study Reveals New Insights Into Human Health

The sequencing of the human genome promised a revolution in medicine, but scientists soon realized that a genetic blueprint alone does not show the body in action.

12 Sep 2023

Establishing the Flour Reference Proteome for Five Wheat Species

The protein composition of the five types of wheat—einkorn, emmer, spelt, durum, and common wheat—and their varieties differ widely.

20 Jun 2023

New Way to Conduct Extensive Proteome Analysis of Urine

Urine is one of the alluring sources for early and sensitive biomarker discovery because it can accumulate and indicate changes in the human body while still being obtained non-invasively.

16 Jun 2023

Squids Use RNA Recording to Change Key Proteins Dynamically

Octopuses, cuttlefish, and squid are members of the diverse family of marine creatures known as cephalopods. They can be found in every ocean, from warm tropical seas that are shallow to cold, abysmal depths.

9 Jun 2023

A High-Throughput Assay for Identifying and Validating ECHS1 Enzyme Genetic Variants

The enzyme variations of mitochondrial enoyl-CoA hydratase short-chain 1 (ECHS1) are dysfunctional. In Japan, they are mostly responsible for mitochondrial disease.

19 May 2023

Getting Insights into Parkinson’s Patients’ Brain Cells Through Stem Cell Research

When the first symptoms of Parkinson’s disease are experienced by a patient, the disease has been evolving for a long period, and the patient might already have lost half of a certain kind of nerve cells in the brain.

27 Apr 2023

Identification of Unique Proteins That Might be Body Weight Regulators

Genetic factors may account for up to 50% of the diversity in body mass index, or BMI, in the population.

5 Apr 2023

Insights into mechanisms impacting NSCLC disease progression

Proteomics is the study and analysis of proteins in a biological system, including their structures, functions, associations, and alterations.

5 Apr 2023

Investigating methanogens to unravel the genetics of temperature adaptation

The history of the Earth has been one of physical extremes-;extreme atmospheric conditions, extreme chemical environments, and extreme temperatures.

28 Mar 2023

Meta-scale approach to quantifying the protein variants in the human body

A key conundrum in biology is why many very simple creatures, such as the widely studied worm C. elegans, have almost as many genes as the human genome, which has about 20,000 genes.

27 Mar 2023

New center to assist in understanding non-coding cancer genome

The MacMillan Center for the Study of the Non-Coding Cancer Genome (MCSNCG) was officially launched by the New York Genome Center (NYGC) on January 18th, 2023.

19 Jan 2023

New open-access database provides a map of the proteome signature

The recently released cancer protein profile database, which was created using AI and machine learning, has helped with cancer prediction medicine. The new open-access Disease Blood Atlas, unveiled by KTH Royal Institute of Technology Professor Mathias Uhlén, gives the first-ever map of the proteome signature in cancer patients’ blood.

11 Jan 2023

Novel insights into the elongation dynamics of eukaryotic cells

The proper functioning of numerous proteins generated in cells by ribosomes is essential for life. This diversified variety of proteins, called proteome, is sustained by the ribosomes’ vigorous translation elongation of amino acid sequences.

6 Jan 2023

Different cancers carry distinctive genetic signatures

After analyzing data from a public repository, CD4-T, CD8-T cells, and Treg cells, a team of researchers led by bioinformatics Mabel Vidal from the University of Concepcion and working with researchers from MELISA Institute and other academic institutions discovered a distinctive genetic signature among subsets of infiltrating T cells of various types of cancer.

4 Nov 2022