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Researchers identify new therapeutic target to fight COVID-19 disease

In COVID-19 patients with severe lung disease, targeting the endothelial cells—that is, cells comprising the blood vessel wall, which control oxygen exchange between the bloodstream and airways—may be an innovative strategy to restore normal function of the lungs.

15 Dec 2020

Study sheds new light on a genetic developmental disorder

The rare hereditary developmental disorder, called Meier-Gorlin syndrome, or MGS for short, causes dwarfism, missing patella, a small brain, small ears, and other skeletal abnormalities. This condition leads to stillbirths and miscarriages in severe cases.

15 Dec 2020

New electrochemical technology helps produce ammonia-based fertilizer from urea

Self-sufficiency in waste management and food cultivation is very important from the perspective of upcoming societies, particularly in highly closed surroundings, like a space station. However, there is still a dearth of technology to realize this dream.

15 Dec 2020

New study dispels concerns that human stem cells contain cancer-causing mutations

Pioneering new research has made a pivotal breakthrough that dispel concerns that human stem cells could contain cancer-causing mutations.

From University of Exeter 15 Dec 2020

Molecular markers in the blood can predict severe COVID-19 outcomes

Molecular markers in the blood shown to be predictive of severe COVID-19 outcomes resulting from SARS-CoV-2 coronavirus infection have been identified in a study by a Chinese research team.

15 Dec 2020

Microglia surveillance helps prevent seizure activity in the brain

An important part of the brain's immune system, cells called microglia constantly extend and retract "branches" from their cell body to survey their environment.

15 Dec 2020

Researchers provide a list of genes implicated in congenital heart disease

Over two million babies, children, and adults in the United States are living with congenital heart disease--a range of birth defects affecting the heart's structure or function.

15 Dec 2020

Using genetic engineering to grow synthetic livers

News-Medical talks to Dr. Mo Ebrahimkhani about his research using genetic engineering together with a machine-learning algorithm to mature a lab-grown 'designer liver organoid'.

From University of Pittsburgh 15 Dec 2020

New combination therapy could be effective in treating aggressive cancers with common mutations

Scientists have long known that therapies that target the cancer-driving MAPK pathway are only effective in a handful of cancers with specific mutations in a cancer gene called BRAF, and these cancers that initially respond to the therapy often end up developing resistance to the treatment, resulting in relapse for many patients.

15 Dec 2020

Newly identified diagnostic marker can help overcome treatment resistance in cervical cancer

Scientists from the University of California, Los Angeles have discovered a promising diagnostic marker that may help predict the response of cervical cancer patients to standard radiation and chemotherapy treatments.

14 Dec 2020

New analysis technique could pave way for major breakthroughs in immunotherapy

In a new study, researchers at Uppsala University have been able to show differences in how Rituximab, a monoclonal antibody drug, interacts with the blood of healthy individuals compared to patients with chronic lymphatic leukaemia.

14 Dec 2020

Study elucidates genes responsible for Glioblastoma invasiveness

One of the hallmarks of Glioblastoma (GBM), the most aggressive type of brain cancer, is its high invasive capacity, which leads to its expansion into the normal brain tissue.

14 Dec 2020

Researchers discover protein crucial for growing life-saving blood stem cells

A group of scientists from the Centre for Genomic Regulation (CRG) in Barcelona and Columbia University in New York City has discovered a protein that is crucial for expanding the usually scarce, life-saving blood stem cells.

11 Dec 2020

New method uses artificial intelligence to study live cells

Researchers have developed a new technique that combines label-free imaging with artificial intelligence to visualize unlabeled live cells over a long time.

11 Dec 2020

Revolutionary CRISPR-based genome editing system treatment destroys cancer cells

Researchers at Tel Aviv University have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers.

11 Dec 2020

New model helps assess the effect of epigenetic changes on gene expression

Researchers have developed a mathematical model to quantitatively assess the impacts of particular epigenetic changes on the transcription rates.

11 Dec 2020

Newly identified Cas9 nucleases can improve genome editing

Scientists have explained two new compact Cas9 nucleases that will possibly extend the Cas9 toolbox for genome editing.

11 Dec 2020

A genetic shortcut to help visualize proteins at work

A group at Gladstone Institutes and UC San Francisco (UCSF) has demonstrated that a large-scale and systematic genetic approach can indeed yield reliable and detailed information on the structure of protein complexes.

11 Dec 2020

Research shows how microbubbles can be used to administer potent cancer drugs

New research has shown how microbubbles carrying powerful cancer drugs can be guided to the site of a tumour using antibodies.

11 Dec 2020

Study shows how microplastics are internalized into living cells

Microplastics have polluted the global environment. These minute particles enter food chains, and end up in the digestive systems of humans and animals.

11 Dec 2020