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Warwick researchers design computational model to enable drug predictions against COVID-19

A computational model of a human lung cell has been used to understand how SARS-CoV-2 draws on human host cell metabolism to reproduce by researchers at the University of Warwick.

From The University of Warwick 26 Nov 2020

Cell survival protein could protect the kidneys from 'bystander' damage during cancer therapy

Australian researchers have identified a protein that could protect the kidneys from 'bystander' damage caused by cancer therapies.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 26 Nov 2020

Research shows lipogenesis process is dysregulated in obesity, fatty liver disease

The production of fat in the human body is essentially regulated by gut hormones.

25 Nov 2020

Study explains why immunotherapy works on certain patients with head and neck cancer

Researchers have found new clues about why certain individuals with head and neck cancer are able to respond to immunotherapy, while others fail to do so.

25 Nov 2020

Scientists identify key biological switch used in plant defense against animal attack

For decades, scientists have known that plants protect themselves from the devastation of hungry caterpillars and other plant-munching animals through sophisticated response systems, the product of millions of years of evolution.

From UC San Diego 25 Nov 2020

Novel targeted therapy blocks critical metabolic pathways in cancer cells

Scientists have designed a new targeted therapy, known as POMHEX, which inhibits vital metabolic pathways in tumor cells containing specific genetic defects.

24 Nov 2020

Study shows how drug-like small molecules regulate the activity of ion channels

Researchers have recently discovered how the function of therapeutically relevant ion channels is regulated by drug-like small molecules.

24 Nov 2020

Scientists use new technology to observe DNA defects in children with Fanconi anemia

Scientists have successfully utilized a novel stem cell technology to examine the skin, specific to a group of living patients, in laboratory settings.

24 Nov 2020

Study: Benefits of immunotherapy can be improved by boosting stem cell activity

Immune-system T cells have been reprogrammed into regenerative stem cell-like memory (TSCM) cells that are long-lived, highly active "super immune cells" with strong antitumor activity, according to new research from Georgetown Lombardi Comprehensive Cancer Center.

24 Nov 2020

Study reveals genomic structures that allow SARS-CoV-2 virus to control the infection process

An international research alliance has visualized the RNA folding structures of the SARS-CoV-2 genome, for the first time.

23 Nov 2020

Researchers use metal-organic frameworks to target prostate cancer cells

Scientists have used metal-organic frameworks to effectively deliver the CRISPR/Cas9 genetic snipping tool into human cancer cells.

23 Nov 2020

Architecture of cell nucleus can change gene activity in plants

Scientists from the University of Tokyo have learned how the layout of the cell nucleus can alter the activity of genes found in plants.

23 Nov 2020

First functional analysis of cytokine IL-15L using rainbow trout

The cytokine family including interleukin-2 and -15 (IL-2 and IL-15) started out in a primitive vertebrate species with three related cytokines IL-2, IL-15, and IL-15-like (IL-15L), all sharing binding capacity for receptor chain IL-15Rα. IL-15L was conserved in fishes, reptiles, and some mammals but lost in humans and mice.

23 Nov 2020

Research sheds light on T cell abnormality in critically ill COVID-19 patients

There is an idea within the coronavirus research field that there is some kind of T cell abnormality in critically ill COVID-19 patients, but specific details have not yet been clarified. To shed light on the problem, a research collaboration based in Kumamoto University (Japan) has performed a genetic analysis of T cells from lung tissue of COVID-19 patients.

23 Nov 2020

Researchers reveal new details of crucial steps involved in the maturation of ribosomes

Ribosomes synthesize all the proteins in cells. Studies mainly done on yeast have revealed much about how ribosomes are put together, but an Ludwig-Maximilians-Universitaet (LMU) in Munich team now reports that ribosome assembly in human cells requires factors that have no counterparts in simpler model organisms.

23 Nov 2020

Cell News and Research

Warwick researchers design computational model to enable drug predictions against COVID-19

Cell survival protein could protect the kidneys from 'bystander' damage during cancer therapy

Research shows lipogenesis process is dysregulated in obesity, fatty liver disease

Study explains why immunotherapy works on certain patients with head and neck cancer

Scientists identify key biological switch used in plant defense against animal attack

Novel targeted therapy blocks critical metabolic pathways in cancer cells

Study shows how drug-like small molecules regulate the activity of ion channels

Scientists use new technology to observe DNA defects in children with Fanconi anemia

Study: Benefits of immunotherapy can be improved by boosting stem cell activity

Study reveals genomic structures that allow SARS-CoV-2 virus to control the infection process

Researchers use metal-organic frameworks to target prostate cancer cells

Architecture of cell nucleus can change gene activity in plants

First functional analysis of cytokine IL-15L using rainbow trout

Research sheds light on T cell abnormality in critically ill COVID-19 patients

Researchers reveal new details of crucial steps involved in the maturation of ribosomes

Biologists unravel how tissue geometry influences cell migration

New research opens up potential target for treating bone disorders

Scientists discover how abnormal proteins unleash latent toxicity in neurodegenerative diseases

Researchers investigate solutions to make cell membranes resistant to coronavirus entry

Researchers prepare biocompatible protocells to pump up blood vessels

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