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High-speed cell sorter rapidly isolates and quantifies cells with complex cellular phenotypes

Isolating individual cells with complex phenotypes – which is key to understanding how these cells function, including to inform disease – is a technological challenge. Now, overcoming this hurdle, researchers present a high-speed cell sorter that uses fluorescence imaging to enable genome-scale studies of complex phenotypes.

21 Jan 2022

New discovery offers insight into how cells maintain the integrity of DNA

Researchers from Case Western Reserve University have identified a new mechanism by which a protein known for repairing damaged DNA also protects the integrity of DNA by preserving its structural shape.

19 Jan 2022

Paradigm4 joins the Tetra Partner Network to leverage Tetra Data into high-performing analytical computing applications for pharmaceutical customers

TetraScience, the R&D Data Cloud company, announced today that Paradigm4, an integrated scientific data analytics company, has joined the Tetra Partner Network so that pharmaceutical customers can accelerate research decision-making using Tetra Data as a foundation for analytical computing.

From TetraScience, Inc. 18 Jan 2022

Daily consumption of more olive oil linked to lower mortality risk

Consuming more than 7 grams (>1/2 tablespoon) of olive oil per day is associated with lower risk of cardiovascular disease mortality, cancer mortality, neurodegenerative disease mortality and respiratory disease mortality, according to a study publishing today in the Journal of the American College of Cardiology.

17 Jan 2022

Pyroptosis is not a one-way ticket, it can be halted and controlled

A study published by researchers at the University of Illinois Chicago describes a new method for analyzing pyroptosis -; the process of cell death that is usually caused by infections and results in excess inflammation in the body -; and shows that process, long thought to be irreversible once initiated, can in fact be halted and controlled.

11 Jan 2022

Scientists develop molecules for myocardial PET and fluorescence bimodal imaging

Heart disease continues to be a leading cause of mortality and morbidity across the globe. Positron emission tomography (PET) has slowly become a remarkable technology of a non-invasive technique for accurately diagnosing cardiac diseases.

11 Jan 2022

Research provides novel insights on cancer immunotherapy

UC San Francisco researchers have defined 12 classes of “immune archetypes” to identify cancer tumors based on data from over 300 patient tumors.

10 Jan 2022

Revealing a Cell's Components through Artificial Intelligence

We speak to Professor Trey Ideker and Yue Qin about their latest in cell biology and how artificial intelligence could be used to discover new components within cells.

From UC San Diego 23 Dec 2021

Novel tool provides an unprecedented view of brain cell activity

To decipher the mysteries behind memory and learning, researchers from Johns Hopkins Medicine developed a system to trace millions of connections amongst brain cells in mice.

22 Dec 2021

New method combines AI and microfluidics to easily barcode individual cells

An innovative new method for more efficient and accurate barcoding of individual cells could help realize faster diagnosis of diseases.

From University of Exeter 21 Dec 2021

Boosting Confocal Microscopy Through Artificial Intelligence

In this interview, we speak to Dr. Hari Shroff from the National Institute of Biomedical Imaging and Bioengineering about his latest research into confocal microscopy.

From National Institute of Biomedical Imaging and Bioengineering (NIBIB) 20 Dec 2021

Researchers develop new method to detect the onset of blood damage at sublethal stage

Red blood cells (RBCs) or erythrocytes are constantly exposed to a "shearing stress" during their circulation in the body. This stress is usually mild and the RBCs are flexible enough to accommodate shape changes in response to it.

17 Dec 2021

Researchers develop novel technique to monitor remote immune mechanisms

The human immune system works hard to maintain an individual’s health and protect against viruses, bacteria, parasites, fungi, and cancerous cells.

17 Dec 2021

Protein protects against heart damage following cancer treatment

Cancer treatment is hard on the body, however for the patient to endure cancer, it is mostly necessary to undergo the treatment.

17 Dec 2021

Scientists find how cells remain dormant for years before awakening to create metastatic cancer

Mount Sinai researchers have solved a major mystery in cancer research: How cancer cells remain dormant for years after they leave a tumor and travel to other parts of the body, before awakening to create metastatic cancer.

14 Dec 2021

Study illustrates the concept of cool microscopy

Fluorescence light microscopy has the unique ability to observe cellular processes over a scale that bridges four orders of magnitude. Yet, its application to living cells is fundamentally limited by the very rapid and unceasing movement of molecules that define its living state.

From The Max Planck Institute 14 Dec 2021

Why is Innovation Critical to Life Sciences Research?

In this interview, we speak to Kirstie Speck from Abcam about the importance of innovation within the life sciences and how its role will change over the next 10 years.

From Abcam 13 Dec 2021

Genetic makeup of neuroblastoma shows marked spatial and temporal variability

Tumors are heterogeneous, which means that different parts of the same tumor can be genetically distinct. This phenomenon, known as intratumor heterogeneity, is steadily gaining in significance within the field of cancer research.

13 Dec 2021

Detachable head-mounted photoacoustic microscope images brain activity in mice

Scientists recently generated the first detachable head-mounted photoacoustic microscope for imaging brain activity in freely roaming mice.

13 Dec 2021

Single-cell spatial analysis may provide information about neoadjuvant therapy for triple-negative breast cancer

A next-generation technology that allows the study of protein expression at the single-cell level and the location of the cells within the tumor microenvironment (TME) was feasible and provided information on the benefit of adding the immune checkpoint inhibitor atezolizumab (Tecentriq) to chemotherapy as neoadjuvant treatment for patients with early high-risk and locally advanced triple negative breast cancer (TNBC), according to results presented at the San Antonio Breast Cancer Symposium, held December 7-10, 2021.

8 Dec 2021