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Researchers uncover a mechanism of flowering plant sperm compaction

Sperm cells have compact bundles of DNA, yet exactly how and why sperm cell nuclei are condensed in flowering plants has been a mystery, until now.

4 Nov 2022

High-throughput quantitative phase microscopy yields promising results

Numerous cellular life processes include the organelles of cells. Their malfunction and the growth and spread of cancer are strongly connected.

4 Nov 2022

New bioprinting platform to replicate tumors in 3D spheroids

Bowel cancer patients could in future benefit from a new 3D bioprinting technology which would use their own cells to replicate the complex cellular environment of solid tumors in 3D models.

3 Nov 2022

Identifying the structure of the SEA complex

The mTOR protein is important for cell growth, proliferation, and survival. Its activity fluctuates according to nutrient availability and growth factors like hormones.

1 Nov 2022

Conserved vacuolar sorting hub regulates autophagic flux in plants

A “hub and spoke” system allows plant cells to effectively coordinate cellular trafficking, especially for cellular recycling, also known as autophagy. Autophagosomes are specialized vesicles that capture hazardous molecules and transport them to the vacuole, where they are destroyed.

21 Oct 2022

Applying machine learning to define significant immune cells

The method correctly categorizes macrophage states, which is crucial since these cells can alter their behavior and function as either pro- or anti-inflammatory agents during an immune response.

20 Oct 2022

New approach to identify cancerous tissue for surgical removal

It is crucial to distinguish between tumors and healthy tissues during cancer surgery. Fluorescent markers can assist in this process by improving tumor contrast during surgery.

13 Oct 2022

Adults with congenital blindness experience striking recoveries of night vision after gene therapy

Adults with a genetic form of childhood-onset blindness experienced striking recoveries of night vision within days of receiving an experimental gene therapy, according to researchers at the Scheie Eye Institute in the Perelman School of Medicine at the University of Pennsylvania.

11 Oct 2022

The science behind gene activation in plants

Researchers explain how a particular variety of GFP can be utilized to allow people to visually observe protein synthesis in this study.

10 Oct 2022

Visualizing subcellular structures with the aid of a brilliant fluorescent protein

The RIKEN discovery of a fluorescent protein produced from a Japanese jellyfish that maintains its brightness even under intense light could have significant positive effects on fluorescence imaging of biological samples.

3 Oct 2022

Transforming “tissue engineering” into a reality

The National Institute of Biomedical Imaging and Bioengineering awarded Case Western Reserve $6.1 million to develop body tissue engineering.

29 Sep 2022

New insights into the regulatory mechanisms of cell fate decisions

The Babraham Institute’s Reik lab’s study has improved the understanding of the function of DNA methylation during the early stages of development.

29 Sep 2022

Cryo-EM solves the decades-old mystery of bacterial movement

Scientists from the University of Virginia School of Medicine and their colleagues have discovered a decades-old mystery regarding how E. coli and other bacteria move.

28 Sep 2022

The exchange of nutrients between the mother and fetus mirrored by ‘placenta-on-a-chip’

Plasmodium falciparum infections can result in placental malaria, which can have serious consequences for both mother and child. Nearly 200,000 newborn fatalities annually from placental malaria, primarily as a result of low birth weight, as well as 10,000 maternal deaths.

27 Sep 2022

New imaging technologies to evade immune responses of Candida albicans

Researchers from the Monash Biomedicine Discovery Institute have demonstrated how the common fungus Candida albicans evades immune responses using newly discovered imaging technologies. The researchers claim that this involves a fungus that can shape-shift in an “alien-like” manner to escape immune cells.

21 Sep 2022

Native 3D structure of the ciliary base witnessed for the first time

Because flaws in the cilia transport system can result in, for example, blindness or cystic kidneys, findings reported in Science offer new understandings of the molecular basis for different diseases.

20 Sep 2022

A new holographic microscope developed to observe neural networks in brain

Scientists headed by Associate Director Wonshik Choi of the Center for Molecular Spectroscopy and Dynamics in the Institute for Basic Science, Professor Kim Moonseok of The Catholic University of Korea, and Professor Myunghwan Choi of Seoul National University designed a new kind of holographic microscope.

19 Sep 2022