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Scientists discover a new left-handed Z-DNA technique to kill hard-to-treat tumors

An international collaboration of scientists has discovered a new technique to kill cancers that are difficult to treat, according to an article published in Nature.

30 May 2022

Researchers determine the novel medical target of angiogenesis for ccRCC patients

Research reported that the DMDRMR/miR-378a-5p/ DAB2IP axis enhances angiogenesis and sunitinib resistance, suggesting that it could be used for patients with ccRCC.

30 May 2022

Study uncovers how CD8+ T cells can divide and produce two distinct daughter cells

An immunological problem has been addressed by scientists at St. Jude Children’s Research Hospital. Despite being genetically identical, a CD8+ T cell can divide and produce two functionally different daughter cells.

27 May 2022

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

Small interfering RNAs, or siRNAs, have the potential to cure tumors by targeting knocking down oncogenes that drive tumor development while avoiding the damage associated with chemotherapy.

25 May 2022

Researchers devise a new treatment approach to cure aggressive brain tumors

Glioblastomas (GBMs) are cancerous tumors of the brain and spinal cord that are incredibly aggressive.

23 May 2022

Cancer biomarkers relying on methylation could forecast tumor type

In cancer management, biomarkers are commonly used to guide treatment decisions and evaluate patient outcomes.

23 May 2022

Research shows how visible hotspots may be easy to target with immune-stimulating drugs

Many cancers include genetic “hotspots,” or sections of DNA that are subject to mutation. For example, a mutation in the TP53 gene is found in more than 50% of all cancers, generally within a narrow DNA range.

18 May 2022

Scientist reveals the impact of mitochondria in metastatic prostate cancer

Prostate cancer that has spread to other regions of the body is commonly treated with hormone treatment, but many individuals develop resistance to it, making their disease more aggressive and potentially fatal.

12 May 2022

Study shows new potential target for CAR T cells to inhibit solid tumors

CAR T therapy, or chimeric antigen receptor T-cell therapy, has revolutionized the treatment of some blood cancers, allowing patients with relapsed or refractory disease to live longer and better lives.

10 May 2022

Gene expression signatures in lymph node cells play an active role in lymphoma development

Researchers from the University of Tsukuba identify gene expression signatures in different types of lymph nodes cells that play an active role in the development of lymphomas.

3 May 2022

Study shows the role of mucosal-associated invariant T cell in mucosal melanomas patients

Many cancer patients have benefited from the development of anti-cancer immunotherapy drugs known as immune checkpoint inhibitors, but patients with mucosal melanomas—melanomas that occur in the mucous membranes of the head, neck, eyes, respiratory system, and genitourinary region rather than on the skin—are highly resistive to immune checkpoint inhibitors for reasons researchers do not fully understand.

29 Apr 2022

Researchers discover a unique origin of severe pediatric brain cancer

A new cause of severe childhood brain cancer has been discovered by scientists.

25 Apr 2022

Study shows how potential target helps to treat lung disease induced by air pollution

According to research published in eLife, scientists have discovered a mechanism that explains how small air pollution particles may cause lung cancer.

25 Apr 2022

Study underscores the crucial role of genomic profiling in diagnosing and grading brain tumors

Patients diagnosed with a type of brain tumor survived for longer when they were treated aggressively with surgery, radiation and chemotherapy.

22 Apr 2022

Manipulating immune cells to suppress the growth of some solid tumors

Cancer researchers at the Case Western Reserve University School of Medicine say they have successfully suppressed the growth of some solid tumors in research models by manipulating immune cells known as a macrophages.

21 Apr 2022

Radioconjugate drugs could change the future of cancer treatment

Many current cancer treatments make patients very sick because even the most targeted treatments kill healthy cells as well as cancer cells. But a new type of treatment called a radioconjugate is getting the attention of oncologists.

21 Apr 2022

Extra copies of DNA explain insensitivity to chemotherapy in germ cell cancer

Extra copies of a piece of DNA partly explain insensitivity to chemotherapy in germ cell cancer, a new study shows.

21 Apr 2022

Microglia regulate the intrinsic excitability of neuronal subtypes differently

A new study reports that immune cell responses to bacteria affect the intrinsic excitability of rat neuronal subtypes differently.

20 Apr 2022

Study provides a deeper understanding of how gene mutations contribute to breast cancer progression

A mutated gene found in more than 20% to 30% of breast cancer recurrences may help tumors become more aggressive and promote metastasis, according to a pair of new studies that uncover mechanisms behind these processes and point to new therapy targets.

From University of Pittsburgh 20 Apr 2022

Researchers analyze the body’s immune cells with blood cancer cells

One in every two people will acquire cancer at some point in their lives, according to the most recent international estimate.

19 Apr 2022

Tumor News and Research

Scientists discover a new left-handed Z-DNA technique to kill hard-to-treat tumors

Researchers determine the novel medical target of angiogenesis for ccRCC patients

Study uncovers how CD8+ T cells can divide and produce two distinct daughter cells

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

Researchers devise a new treatment approach to cure aggressive brain tumors

Cancer biomarkers relying on methylation could forecast tumor type

Research shows how visible hotspots may be easy to target with immune-stimulating drugs

Scientist reveals the impact of mitochondria in metastatic prostate cancer

Study shows new potential target for CAR T cells to inhibit solid tumors

Gene expression signatures in lymph node cells play an active role in lymphoma development

Study shows the role of mucosal-associated invariant T cell in mucosal melanomas patients

Researchers discover a unique origin of severe pediatric brain cancer

Study shows how potential target helps to treat lung disease induced by air pollution

Study underscores the crucial role of genomic profiling in diagnosing and grading brain tumors

Manipulating immune cells to suppress the growth of some solid tumors

Radioconjugate drugs could change the future of cancer treatment

Extra copies of DNA explain insensitivity to chemotherapy in germ cell cancer

Microglia regulate the intrinsic excitability of neuronal subtypes differently

Study provides a deeper understanding of how gene mutations contribute to breast cancer progression

Researchers analyze the body’s immune cells with blood cancer cells

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