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New method targets hidden HIV viral reservoirs during antiretroviral therapy

Scientists at The Wistar Institute may have discovered a new way of identifying and targeting hidden HIV viral reservoirs during treatment with antiretroviral therapy (ART).

10 Aug 2020

Study indicates a powerful treatment for pulmonary fibrosis

A pre-clinical study led by scientists at Cincinnati Children's demonstrates that in mice the drug barasertib reverses the activation of fibroblasts that cause dangerous scar tissue to build up in the lungs of people with idiopathic pulmonary fibrosis (IPF).

7 Aug 2020

Scientists explore the role of epigenetic regulator factors in embryonic development

A research team at the Max Planck Institute for Molecular Genetics in Berlin has explored the role of factors in embryonic development that do not alter the sequence of DNA, but only epigenetically modify its "packaging".

5 Aug 2020

New method reveals the dynamics of cell development and gene activity

Studies on cellular dynamics are vital to interpret the development of cells and the progression of various diseases.

5 Aug 2020

New study may offer a novel, potential target for treating breast cancer

According to researchers, G-quadruplexes have been demonstrated to play a crucial role in specific types of breast cancer for the first time.

5 Aug 2020

Study uncovers molecular mechanism of metabolite-mediated epigenome involved in organismal aging

Scientists have recently demonstrated that acetyl-CoA connects mitochondrial stress to the nuclear epigenome through the NuRD complex.

4 Aug 2020

Hudsonalpha researchers help elucidate functional elements of the genome

Although the Human Genome Project sequenced a nearly-complete human genome almost 20 years ago, only about two percent of the genes in the human genome have been extensively studied and identified as protein-coding genes. Proteins form the basis of living tissues and play a central role in biological processes.

3 Aug 2020

New methods to regulate enzymes involved in SARS-CoV-2 virus infection

A research team from the HSE University has designed innovative methods for controlling the expression of TMPRSS2 and ACE2 enzymes.

30 Jul 2020

New tool predicts and identifies novel genes involved in various biological processes

Chromatin plays a significant role in the silencing and activation of gene transcription, and establish the fate of the cells during development.

30 Jul 2020

Researchers map DNA methylation changes to study developmental disorders

Researchers performed a study in which they created a total of 168 new maps of chemical marks on DNA strands, known as methylation, in developing mice.

30 Jul 2020

Higher levels of specific protein linked with severity of COVID-19 symptoms

A new study found raised levels of transforming growth factor beta-induced protein (TGFBIp) in blood sampled from roughly 100 people hospitalized for COVID-19, and further found that elevated levels of both the normal and acetylated forms of TGFBIp correlated with the severity of disease symptoms in these patients.

27 Jul 2020

Epigenomic data can help characterize genes that play key role in cancer progression

As cancer cells evolve, many of their genes become overactive while others are turned down. These genetic changes can help tumors grow out of control and become more aggressive, adapt to changing conditions, and eventually lead the tumor to metastasize and spread elsewhere in the body.

From Massachusetts Institute of Technology (MIT) 24 Jul 2020

Study explores the genetic and molecular basis of PD-L2 regulation

In immune-related disorders, therapy often involves identifying the molecules responsible for immune dysregulation and targeting them using drugs.

22 Jul 2020

Silver-plated gold nanostars could be used to detect early cancer biomarkers

Biomedical engineers at Duke University have engineered a method for simultaneously detecting the presence of multiple specific microRNAs in RNA extracted from tissue samples without the need for labeling or target amplification.

22 Jul 2020

Researchers image the formation of four-stranded DNA in living human cells

The development of four-stranded DNA has been monitored in the living cells of human beings, enabling researchers to observe its potential role in cancer.

21 Jul 2020

Newly discovered protein could be an important target to prevent prostate cancer metastases

Researchers from Boston University School of Medicine (BUSM) have discovered that the protein BRD4 could be an important new target to prevent castration-resistant prostate cancer metastases.

21 Jul 2020

Rapid laboratory test can aid in early diagnosis of COVID-19 in patients

A rapid laboratory test, the eosinophil count, readily obtained from a routine complete blood cell count (CBC) can aid in the early recognition of COVID-19 in patients, as well as provide prognostic information, according to new research in The Journal of the American Osteopathic Association.

20 Jul 2020

Transcription News and Research

New method targets hidden HIV viral reservoirs during antiretroviral therapy

Study indicates a powerful treatment for pulmonary fibrosis

Scientists explore the role of epigenetic regulator factors in embryonic development

New method reveals the dynamics of cell development and gene activity

New study may offer a novel, potential target for treating breast cancer

Study uncovers molecular mechanism of metabolite-mediated epigenome involved in organismal aging

Hudsonalpha researchers help elucidate functional elements of the genome

New methods to regulate enzymes involved in SARS-CoV-2 virus infection

New tool predicts and identifies novel genes involved in various biological processes

Researchers map DNA methylation changes to study developmental disorders

Higher levels of specific protein linked with severity of COVID-19 symptoms

Epigenomic data can help characterize genes that play key role in cancer progression

Study explores the genetic and molecular basis of PD-L2 regulation

Silver-plated gold nanostars could be used to detect early cancer biomarkers

Researchers image the formation of four-stranded DNA in living human cells

Newly discovered protein could be an important target to prevent prostate cancer metastases

Rapid laboratory test can aid in early diagnosis of COVID-19 in patients

Type 1 interferon deficiency in the blood could be a hallmark of severe COVID-19

Researchers to develop new ways to prevent esophageal cancer

Metabolomics can help understand the impact of calorie-restricted diets on aging

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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