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'Survival of the fittest': How meiotic drivers shape the evolution of gamete formation

It can be hard to dispute the common adage 'survival of the fittest'. After all, "most of the genes in the genome are there because they're doing something good," says Sarah Zanders, PhD, assistant investigator at the Stowers Institute for Medical Research

18 Aug 2020

Study shows how mitochondrial defects lead to neurodevelopmental diseases

The tiny organelles mitochondria supply the energy crucial for all cells in the human body, specifically in the brain that consumes an excessive amount of fuel.

18 Aug 2020

Study shows how proteins act as a defense mechanism to protect their own DNA

Viruses usually inject their DNA into a host cell to multiply. As soon as this foreign material penetrates the intracellular fluid, it activates a defense mechanism called the cGAS-STING pathway.

18 Aug 2020

Study shows how viruses escape the immune system

Scientists from the University of Otago have gained a deeper understanding of how viruses work and escape the immune system. The team is presently using this finding to find out more about the COVID-19 pandemic.

18 Aug 2020

Ultra-low voltage electricity effectively damages and kills bacteria

Ultra-low voltage electricity is effective at killing bacteria because it causes membranes that surround bacteria to leak, according to a new study by University of Arkansas researchers. The research advances work to fight drug-resistant bacteria.

18 Aug 2020

New discovery offers hope for people at risk of antibiotic-resistant infections

There is new hope for approximately 700,000 people who die each year from antibiotic resistant infections, with University of Queensland researchers discovering how bacteria share antibiotic-resistance genes.

18 Aug 2020

High-speed AFM enables real-time visualization of influenza A hemagglutinin during viral entry

Unlike living organisms, to avoid extinction, viruses need to hijack living host machineries to generate new viruses.

18 Aug 2020

Extrachromosomal DNA with potential to cause cancer drives poor patient outcomes

The multiplication of genes located in extrachromosomal DNA that have the potential to cause cancer drives poor patient outcomes across many cancer types, according to a Nature Genetics study published Aug. 17, 2020 by a team of researchers including Professors Vineet Bafna and Dr.Paul Mischel of the University of California San Diego and Professor Roel Verhaak of Jackson Laboratories.

From UC San Diego 18 Aug 2020

Switching off 'master regulator' may offer neuroprotection from Parkinson's-related damage

Switching off a molecular "master regulator" may protect the brain from inflammatory damage and neurodegeneration in Parkinson's disease, reports a study published today in Nature Neuroscience.

18 Aug 2020

Genome analysis helps identify 568 cancer driver genes

Analysis of the genomes of 28,000 tumors from 66 types of cancer has led to the identification of 568 cancer driver gene.

18 Aug 2020

Scientists discover bacteria's secret weapon to evade immune responses

Monash Biomedicine Discovery Institute scientists have discovered a previously unknown method used by bacteria to evade immune responses.

18 Aug 2020

Regulating cancer stemness using combination of nanotechnology and genetic engineering

The development of chemotherapeutic agents with selective anti-cancer activities is increasingly unattractive due to the emergence of resistance, poor targeting of cancer tissues, and subsequent metastasis.

18 Aug 2020

Rotating microscope can track and measure behavior of ocean organisms

Like spirits passing between worlds, billions of invisible beings rise to meet the starlight, then descend into darkness at sunrise. Microscopic plankton's daily journey between the ocean's depths and surface holds the key to understanding crucial planetary processes, but has remained largely a mystery until now.

18 Aug 2020

Novel receptor protein can be a promising treatment for COVID-19

A novel receptor protein that binds to the SARS-CoV-2 virus and prevents it from entering cells may hold promise for treating COVID-19 and other coronavirus-related diseases, according to research published online Aug. 4 in the journal SCIENCE.

18 Aug 2020

Researchers show how two X chromosomes communicate during embryo development

Researchers at Massachusetts General Hospital (MGH) have solved a mystery that has long puzzled scientists: How do the bodies of female humans and all other mammals decide which of the two X chromosomes it carries in each cell should be active and which one should be silent?

18 Aug 2020

SIDT1 in the mammalian stomach mediates absorption of dietary miRNAs

In a new study published in Cell Research, Chen-Yu Zhang's group at Nanjing University School of Life Sciences, China, reports that SIDT1 in the mammalian stomach mediates host uptake of dietary and orally administered microRNAs (miRNAs), thus exerting biological functions in the host.

18 Aug 2020

New nanoparticle formulation could stop tooth decay without killing oral bacteria

Oral bacteria are ready to spring into action the moment a dental hygienist finishes scraping plaque off a patient's teeth.

18 Aug 2020

New fluorescent probe to detect damaged mitochondria could help treat neurodegenerative disorders

Scientists have developed a new, multipurpose probe that is capable of detecting the programmed destruction of faulty mitochondria with pinpoint precision.

17 Aug 2020

Researchers identify a new gene to treat multiple sclerosis

Multiple sclerosis, or MS, is a disease that affects the central nervous system and can eventually lead to muscle tremors and thus loss of balance.

17 Aug 2020

NIH-supported research delineates how genetic variations cause atopic dermatitis

New research supported by the National Institutes of Health delineates how two relatively common variations in a gene called KIF3A are responsible for an impaired skin barrier that allows increased water loss from the skin, promoting the development of atopic dermatitis, commonly known as eczema.

17 Aug 2020

Cell News and Research

'Survival of the fittest': How meiotic drivers shape the evolution of gamete formation

Study shows how mitochondrial defects lead to neurodevelopmental diseases

Study shows how proteins act as a defense mechanism to protect their own DNA

Study shows how viruses escape the immune system

Ultra-low voltage electricity effectively damages and kills bacteria

New discovery offers hope for people at risk of antibiotic-resistant infections

High-speed AFM enables real-time visualization of influenza A hemagglutinin during viral entry

Extrachromosomal DNA with potential to cause cancer drives poor patient outcomes

Switching off 'master regulator' may offer neuroprotection from Parkinson's-related damage

Genome analysis helps identify 568 cancer driver genes

Scientists discover bacteria's secret weapon to evade immune responses

Regulating cancer stemness using combination of nanotechnology and genetic engineering

Rotating microscope can track and measure behavior of ocean organisms

Novel receptor protein can be a promising treatment for COVID-19

Researchers show how two X chromosomes communicate during embryo development

SIDT1 in the mammalian stomach mediates absorption of dietary miRNAs

New nanoparticle formulation could stop tooth decay without killing oral bacteria

New fluorescent probe to detect damaged mitochondria could help treat neurodegenerative disorders

Researchers identify a new gene to treat multiple sclerosis

NIH-supported research delineates how genetic variations cause atopic dermatitis

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