Immune System News and Research

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MicroRNA’s influence on lupus disease inflammation

Researchers from Nagoya University’s Graduate School of Medicine in Japan have uncovered how microRNA (miRNA) affects inflammation in mice with lupus. They discovered two downregulated miRNAs in the disease along with a rare circumstance where several miRNAs control the same set of genes.

27 Jan 2023

New revelations on the immune system’s defenses against infections

Cells competing for a place in a germinal center confront a tough admissions process. Germinal centers, which form following exposure to a pathogen or vaccine, serve as a kind of immune system training academy, assisting B cells in refining their response to the threat.

18 Jan 2023

Detecting the extent of natural selection over time

Institut Pasteur, Université Paris Cité, the CNRS, and the Collège de France researchers have employed paleogenomics to trace 10,000 years of human immune system evolution. They examined the genomes of over 2,800 individuals who lived in Europe over the past 10 millennia.

From Institut Pasteur 18 Jan 2023

New solution to treat diseases caused by exaggerated inflammation

A recent study guided by the Instituto Gulbenkian de Ciência (IGC) shows how anticancer drugs reduce inflammation, establishing them as prospective sepsis treatments.

11 Jan 2023

Emerging viruses could be easily detected with a simple nasal swab

As the COVID-19 pandemic demonstrated, potentially harmful new viruses can spread throughout the population long before the system for monitoring global public health can catch them.

5 Jan 2023

Common food dye can be a potential dietary trigger for IBDs, study shows

Long-term consumption of Allura Red food dye can be a potential trigger of inflammatory bowel diseases (IBDs), Crohn's disease and ulcerative colitis, says McMaster University's Waliul Khan.

21 Dec 2022

Key immune alarm protein that regulates inflammation identified

Trinity researchers have made a significant advance in understanding how inflammation is controlled. They recently discovered that a crucial immunological alarm protein that was previously thought to quiet the immune response apparently performs the opposite.

20 Dec 2022

The potential of cellular “glue” in regenerative medicine

Scientists at UC San Francisco have created molecules that function as “cellular glue,” enabling them to precisely control how cells adhere to one another. The discovery is a significant step toward regenerative medicine’s long-term goal of creating new tissues and organs.

14 Dec 2022

Molecular regulation underlying emergency hematopoiesis uncovered

If the body’s emergency hematopoiesis program activates, it signifies an alert state of the immune system and serves two functions: In comparison to “normal mode” hematopoiesis, the emergency program results in enhanced replacement of immune cells consumed during infections or inflammations.

12 Dec 2022

Stress hormones produced by salmon could be leading to increased infections

Fish farming is a crucial industry in Norway, and salmon is by far the most important species. So it's alarming that bacterial diseases are on the rise at the massive sea farms where salmon are raised.

7 Dec 2022

Microglial cells trigger inflammatory protective mechanisms in the immune system

Microglia, the brain’s own immune cells, are present in the central nervous system.

1 Dec 2022

Acute infection disrupts the healthy balance between the good and bad gut microbes

Rutgers researchers examined the impact of COVID-19 on patients’ microbiomes, the group of microbes that live in and on the human body.

From Rutgers University 30 Nov 2022

Insight into the treatment for Crimean Congo Hemorrhagic Fever Virus

The Crimean Congo Hemorrhagic Fever Virus can be prevented by therapeutically relevant human monoclonal antibodies, according to research led by the University of California, Riverside.

30 Nov 2022

Study unravels a novel function of the gene scissors

Many years earlier, the CRISPR/Cas9 gene scissors have been making a sensation in science and medicine. This new tool of molecular biology consists of its origins in an ancient bacterial immune system.

28 Nov 2022

AI creates artificial DNA to control cell protein production

Researchers at Chalmers University of Technology in Sweden have developed synthetic DNA that uses artificial intelligence to control the production of proteins in cells.

25 Nov 2022

Improving potential of cellular therapies with CAR T therapy

CAR T cells, or engineered immune cells, have demonstrated to the world the potential of customized immunotherapies to treat blood cancers. Researchers have just released highly encouraging preliminary data for CAR T therapy in a small group of lupus patients.

25 Nov 2022

Breakthrough on the way to new therapeutic strategies

As far as the field of cancer research is concerned, hollow spheres composed of MYC proteins sets the stage. Researchers from Würzburg have found them out and have reported this discovery in the Nature journal.

25 Nov 2022

Novel approach increases the protein production efficiency of synthetic mRNAs

A group of synthetic biologists at the Hong Kong University of Science and Technology (HKUST) recently figured out a way to improve the efficiency of synthetic mRNA protein production by up to tenfold.

24 Nov 2022

Chemically attenuated live DNA virus vaccine prevents viral infection

Rutgers researchers have devised a new way to prevent viral infections: a live-attenuated, replication-defective DNA virus vaccine that utilizes the substance centanamycin to create an altered virus for vaccine development.

From Rutgers University 22 Nov 2022

Mitochondria play a crucial role in the regulation of the NF-κB signaling pathway

Mitochondria are highly regarded as the cell's powerhouse. However, these cellular organelles are essential for more than only energy production: Professor Konstanze Winklhofer and her colleagues at Ruhr University Bochum’s Faculty of Medicine have found that mitochondria play an essential role in signal transduction in innate immune pathways.

21 Nov 2022