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Novel, more accurate computational tool for long-read RNA sequencing developed

On the journey from gene to protein, a nascent RNA molecule can be cut and joined, or spliced, in different ways before being translated into a protein.

31 Jan 2023

Unboxing the mystery genome black box with the DNA sequencing method

Researchers from the University of Cambridge have described a new DNA sequencing technique that can find out where and how small molecule drugs interact with the targeted genome in a study that was published in the journal Nature Biotechnology.

26 Jan 2023

New computational tool for long-read RNA sequencing

An evolving RNA molecule can be cut and joined, or spliced, in various ways on the path from gene to protein before being translated into a protein. Using a technique called alternative splicing, multiple proteins can be encoded by a single gene.

24 Jan 2023

New toolkit enables researchers to map an individual’s RNA data to a much richer reference

Examining the gene expression of a person needs mapping the RNA landscape to a standard reference. This is done to gain an understanding of the degree to which genes are “turned on” and execute the functions in the body.

From University of California Santa Cruz 18 Jan 2023

'Green' products recycled from human excreta can be excellent fertilizers for agriculture

To tackle the climate crisis, biodiversity loss, and pollution, humanity will need to move to a circular economy, where all resources are recycled.

17 Jan 2023

Enzymes hold the answer to understanding how DNA mutates

According to recent research from the University of Surrey, enzymes, which are essential for regulating how cells replicate in the human body, could be the very component that encourages DNA to spontaneously mutate, leading to potentially permanent genetic errors.

From University of Surrey 17 Nov 2022

Reservoir ensures sustainable use of reagents

Manufactured to the ANSI/SLAS standard, the range of reagent reservoirs from Porvair Sciences are designed for simple integration into any automated liquid handling system.

From Porvair Sciences Limited 24 Aug 2022

Study shows how two matching DNA strands hybridize to generate double-stranded DNA

Nanoscientists and theoretical physicists from UNSW Medicine & Health’s EMBL Australia Node in Single Molecule Science collaborated to decipher the intricate mechanics of determining how quickly two matched strands of DNA may completely come together—or hybridize—to generate double-stranded DNA. Their results were reported in Nucleic Acids Research.

From The University of New South Wales (UNSW) 28 Jul 2022

New technique shows how tRNA folding changes help to treat RNA-linked diseases

Researchers have developed a novel technique to analyze the composition and quantity of “transfer RNAs, which are tiny, chemically modified RNAs involved in protein synthesis.

From Penn State University 1 Jul 2022

Study shows how nanotechnology may help for structural research of RNA molecules

Humans live in a world created and managed by RNA—the genetic molecule DNA’s equally important sibling.

3 May 2022

Researchers analyze the potential role of mRNA in drug development and novel therapies

In latest years, messenger RNA—the DNA’s close relative in the complex process of turning a string of genetic blueprints into a properly functioning organism—has gotten a lot of attention in the scientific and medical community.

29 Apr 2022

National DNA Day 2022: an interview with Professor Matthew Cobb

To celebrate National DNA Day 2022, we spoke to science communicator Professor Matthew Cobb.

From The University of Manchester 25 Apr 2022

National DNA Day 2022: PacBio HiFi Sequencing Contributes to First Complete Human Genome

To celebrate National DNA Day 2022, News-Medical speaks to Jonas Korlach, Chief Scientific Officer of PacBio.

25 Apr 2022

Study highlights an effective technique to overcome the rice yield constraint

Tradeoffs between diverse agronomic traits constrain crop breeding to a great extent. Because gene pleiotropy causes many of these tradeoffs, lowering gene pleiotropy may make it simpler to overcome tradeoffs in plant breeding.

22 Apr 2022

Researchers analyze single-cell DNA sequencing for having a significant role in Alzheimer’s disease

The loss of functional neurons in the brain is a characteristic of Alzheimer’s disease. What, on the other hand, is the source of this loss?

21 Apr 2022

Researchers develop epigenetic methods for effective cancer treatments

If genetics is concerned with gene sequencing, epigenetics is concerned with how genes are employed (or not) by a cell.

19 Apr 2022

INTEGRA commits to sustainability

INTEGRA Biosciences continues to foster its sustainable approach to supplying high quality laboratory tools to research facilities across the globe.

From INTEGRA Biosciences 13 Apr 2022

Scientists produce the first complete, gapless sequence of a human genome

Two decades after the Human Genome Project delivered the first preliminary human genome sequence, researchers have published the first full, gapless sequence of a human genome.

From National Human Genome Research Institute (NHGRI) 4 Apr 2022

New long-lived biological computers could potentially persist inside cells

Tiny biological computers made of DNA could revolutionize the way we diagnose and treat a slew of diseases, once the technology is fully fleshed out.

From National Institute of Standards and Technology (NIST) 24 Mar 2022

Researchers use GP2 and UMOD to prevent urinary tract infection

A team led by Karolinska Institute used AI and structural biology to learn more about two similar proteins that protect against bacterial infection in the urinary tract.

16 Mar 2022