Neutrophils News and Research

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Scientists identify a genetic basis for ANCA-associated vasculitis

Autoimmune disease is fundamentally a mystery: whyever should an organism systematically set out to harm itself? Now, researchers at the University of Tsukuba have identified a genetic basis for anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis, an autoimmune systemic disease that damages organs by targeting small blood vessels in a genetic association study.

5 Nov 2020

'Training’ the innate immunity may improve the success of immunotherapy

Immunotherapies, such as checkpoint inhibitor drugs, have made worlds of difference for the treatment of cancer. Most clinicians and scientists understand these drugs to act on what's known as the adaptive immune system, the T cells and B cells that respond to specific threats to the body.

30 Oct 2020

Anti-inflammatory mediator could play key role in wound healing

"Wound healing is one of the most complex biological processes," writes Professor Kazumitsu Sugiura and Dr Kenta Saito from Fujita Health University, Japan, in their article recently published in Nature's Scientific Reports.

27 Oct 2020

Study pinpoints specific protein involved in the mass production of antibodies

A team of researchers has discovered how a specific protein called JAGN1 plays a crucial role in the production of antibodies.

17 Sep 2020

Study shows immune cells contribute to brain infection

A new study shows how the immune system has a damaging effect on a severe brain condition, which is most commonly caused by the cold sore virus.

17 Sep 2020

Sticky DNA webs may cause tissue damage linked to severe COVID-19

Sticky webs of DNA released from immune cells known as neutrophils may cause much of the tissue damage associated with severe COVID-19 infections, according to two new studies published on September 14 in the Journal of Experimental Medicine (JEM).

15 Sep 2020

LJI scientists tracked down rare stem cells that generate neutrophils in humans

Neutrophils are the warriors of the immune system. They are always ready to spring to action to help heal injuries or fight off disease. Unless, that is, something goes wrong in their developmental process.

19 Aug 2020

Study may point to new therapeutic options for COVID-19

Contrary to what has been generally assumed so far, a severe course of COVID-19 does not solely result in a strong immune reaction - rather, the immune response is caught in a continuous loop of activation and inhibition.

7 Aug 2020

Study shows how psychological stress leads to debilitating vessel-clogging episodes

Researchers from the Albert Einstein College of Medicine have demonstrated that chronic psychological stress can result in painful vessel-clogging episodes—a frequent cause of hospitalizations and the most typical complication of sickle-cell disease or SCD.

31 Jul 2020