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Novel Tridimensional Anticancer Agents Have the Ability to Overcome Drug Resistance in Cancer Cells

A research team co-led by chemists from City University of Hong Kong recently discovered novel, highly effective anticancer agents with tridimensional structures, which have high anticancer activity, low toxicity and the ability to overcome drug resistance in cancer cells.

7 Apr 2023

CrestOptics Launches CICERO System to Provide All-in-One Solution for Widefield and Spinning Disk Confocal Microscopy

CrestOptics S.p.A., a manufacturer of high-end microscopy solutions and advanced systems for fluorescence microscopy and diagnostic applications, today announced the launch of its new spinning disk confocal microscope system, CICERO.

3 Apr 2023

FDA-approved compound promotes photoreceptor survival in lab models of inherited retinal ciliopathy

A National Eye Institute-led team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10), an inherited retinal ciliopathy disease that often results in severe visual impairment or blindness in early childhood.

30 Mar 2023

Determining the structure of protein pumps using cryo-EM

A rare, genetic disorder known as Hailey-Hailey disease causes patches of blisters to develop mainly in the folds of skin under the breasts, in the groin, and the armpits.

29 Mar 2023

How specialized plant “train tracks” can be used to feed the expanding population

A new study will examine the possibility that specialized plant “train tracks” that transport chemicals within cells could help in feeding the world’s expanding population.

From The University of Warwick 23 Mar 2023

Stem cells must take out the trash to protect against age-related diseases

In humanity's ongoing quest for the elixir of life, the science keeps pointing to stem cells. Research increasingly shows that maintaining stem cell fitness promotes a long healthspan, and new findings show keeping stem cells clean and tidy is an integral step.

22 Mar 2023

Perspectives on nucleolar DNA damage response in the fight against cancer

Cancer, which affects so many people each year, relies on proteins to proliferate throughout the body. Scientists are damaging the disease’s protein factories as part of a new tactic to combat the widespread disease.

20 Mar 2023

DZNE scientists discover major role of centrosome in neuronal migration

Researchers from the DZNE have solved an important puzzle in neurobiology: the wiring and the movement of nerve cells are interwoven, but separately controlled.

16 Feb 2023

Versatile molecular toolbox expands the scope of gene regulation

Rice University scientists have enlisted widely used cancer therapy systems to control gene expression in mammalian cells, a feat of synthetic biology that could change how diseases are treated.

15 Feb 2023

Figuring out how cells safeguard their genomes during replication

Cells zealously protect the integrity of their genomes, because damage can lead to cancer or cell death. The genome, a cell’s complete set of DNA, is most vulnerable while it is being duplicated before a cell divides.

26 Jan 2023

Discovery of a new cellular element crucial to sense of smell

Researchers at Umeå University have found an organelle, a previously unidentified cellular component, inside the neurons that are responsible for the ability to smell. The finding might have repercussions for future studies on COVID-19 symptoms like impaired smell sense.

5 Jan 2023

Conserved vacuolar sorting hub regulates autophagic flux in plants

A “hub and spoke” system allows plant cells to effectively coordinate cellular trafficking, especially for cellular recycling, also known as autophagy. Autophagosomes are specialized vesicles that capture hazardous molecules and transport them to the vacuole, where they are destroyed.

21 Oct 2022

Optogenetic control of mitochondria–lysosome contacts induce mitochondrial fission with spatiotemporal accuracy

Researchers from UC, the University of Illinois Urbana-Champaign, and the University at Buffalo demonstrated that light-activated proteins can help normalize dysfunction within cells.

8 Aug 2022

SLFN11’s surveillance part in protein homeostasis

On July 25th, 2022, a new study perspective called “SLFN11’s surveillance role in protein homeostasis” was published in Volume 9 of Oncoscience.

8 Aug 2022

New gene may affect the upper motor neuron cells in the nervous system, study reveals

A recent genetic finding supports the theory that abnormal lipid (fat) transport pathways inside brain cells cause motor neuron degenerative disorders.

From University of Exeter 20 Jun 2022

Researchers discover how the protein content of centrosomes may vary on cell type

The centrosome is the organelle that organizes the cytoskeleton during cell division, which is an important role in species ranging from yeast to humans. Due to its broad functions, scientists previously considered that the centrosome was quite similar in all cells.

17 Jun 2022

Researchers analyze and demonstrate how organelles divide into cells

The research, headed by Professor Michael Schrader of the University of Exeter, looked at peroxisome dynamics and discovered new ways for them to divide.

From University of Exeter 10 Jun 2022

New framework to boost crop growth by incorporating strategies from a fast-growing algal species

A new study provides a framework to boost crop growth by incorporating a strategy adopted from a fast-growing species of green algae.

20 May 2022

Researchers identify jellyfish’s stinging cells to promote new cell function

According to a recent Cornell study, the cnidocytes—or stinging cells—that are found in sea anemones, hydrae, corals, and jellyfish and make us cautious while wading in the ocean are also an ideal way of understanding the creation of new cell types.

18 May 2022

Researchers discover protein that enhances muscle mass

Humans are not just pumping iron in the gym, or not just oxygenating muscle cells, which keeps those muscles healthy, powerful, and developing—a process known as hypertrophy—that is defined as an increase in muscle mass, caused by an increase in muscle cell size.

29 Apr 2022