therapeutics News and Research

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Changes in mitochondria could cause health problems in Space

News-Medical speaks to Dr. Beheshti from NASA about his latest research that investigated whether changes in mitochondria could cause health problems in Space.

From NASA 29 Jan 2021

Mice study provides new data for studying aging and age-related diseases

A novel compound that increases lifespan in a small nematode worm has been shown to delay bone loss in aging mice.

28 Jan 2021

Researchers identify a new way to stop COVID-19 virus

While the world awaits broad distribution of COVID-19 vaccines, researchers at Ohio University just published highly significant and timely results in the search for another way to stop the virus -- by disrupting its RNA and its ability to reproduce.

22 Jan 2021

Investigational antisense medicine lowers disease burden, reduces myeloma cell abundance in mice

Many patients with multiple myeloma, a type of blood cancer, eventually develop resistance to one treatment after another. That's in part because cancer stem cells drive the disease -- cells that continually self-renew. If a therapy can't completely destroy these malignant stem cells, the cancer is likely to keep coming back.

From UC San Diego 21 Jan 2021

Researchers use heat map data to reverse engineer chromosome models

Genome analysis can provide information on genes and their location on a strand of DNA, but such analysis reveals little about their spatial location in relation to one another within chromosomes -- the highly complex, three-dimensional structures that hold genetic information.

15 Jan 2021

Targeting RNA splicing can trigger antiviral immune pathways in triple-negative breast cancers

Researchers at Baylor College of Medicine have discovered how therapeutics targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers (TNBC) to trigger tumor cell death and signal the body's immune response.

15 Jan 2021

Nanobodies can prevent entry of SARS-CoV-2 coronavirus into human cells

Researchers at Karolinska Institutet in Sweden have developed, in collaboration with researchers in Germany and the U.S., new small antibodies, also known as nanobodies, which prevent the SARS-CoV-2 coronavirus from entering human cells.

13 Jan 2021

Researchers develop novel nanobodies against SARS coronavirus-2

An international research team led by the University of Bonn has identified and further developed novel antibody fragments against the SARS coronavirus-2. These "nanobodies" are much smaller than the classic antibodies used to treat US President Donald Trump, for example.

13 Jan 2021

New discovery helps explain how COVID-19 suppresses the body’s immune response

Seeking to understand why COVID-19 is able to suppress the body's immune response, new research from the USC Leonard Davis School of Gerontology suggests that mitochondria are one of the first lines of defense against COVID-19 and identifies key differences in how SARS-CoV-2, the virus that causes COVID-19, interacts with mitochondrial genes when compared to other viruses.

12 Jan 2021

Novel treatments could cut the death rate from dengue, Zika, West Nile viruses

A new study led by researchers from The University of Queensland (UQ) could help identify new therapies to reduce the global death rate caused by Zika, West Nile, and dengue viruses.

8 Jan 2021

$Loss of enzymatic processes can increase the risk of bone fracture$

Loss of enzymatic processes can increase the risk of bone fracture

When enzymatic processes decline inside the body, they can increase the risk of bone fracture in a person.

8 Jan 2021

Scientists resolve long-standing debate over key mechanism involved in gene silencing

Scientists from Massachusetts General Hospital (MGH) have resolved a long-standing debate over how crucial gene-silencing protein detects its targets.

5 Jan 2021

Chromosomal instability is associated with cancer's aggressiveness

Cancer cells are known for spreading genetic chaos. As cancer cells divide, DNA segments and even whole chromosomes can be duplicated, mutated, or lost altogether.

29 Dec 2020

Autobahn Labs announces strategic drug discovery collaboration with UCSF

Autobahn Labs, a virtual incubator partnering with top academic and research institutions to catalyze early-stage drug discovery and development, today announced a strategic collaboration with the University of California San Francisco (UCSF).

21 Dec 2020

Novel compounds may lead to potential treatment for rare terminal childhood illness

Researchers have discovered a method to “rescue” genetically mutated cells, providing opportunities to develop a new treatment for mitochondrial disease.

From University of Exeter 21 Dec 2020

Scientists find new way to prevent cancer relapse after immunotherapy

Mount Sinai researchers have solved one of the enduring mysteries of cancer immunotherapy: Why does it completely eliminate tumors in many patients, even when not all the cells in those tumors have the molecular target that the therapy is aimed at?

18 Dec 2020

Researchers detect new immune cells that act as major driver of breast cancer growth

Several breast cancer immunotherapies have had only minimal success in treating the aggressive forms of this disease.

17 Dec 2020

Researchers identify suitable biocatalyst for designing COVID-19 vaccine

The chemical substance class of nucleosides is attracting a great deal of interest, and this can be attributed to the ongoing COVID 19 pandemic.

17 Dec 2020

Tumor's stiff-arm tactic restricts the effectiveness of checkpoint inhibitors

In a paper just published in the Journal for the Immunotherapy of Cancer (doi:10.1136/jitc-2020-001712), Dr. Herbert, Head of Discovery at InsideOutBio, asks whether cancer cells stiff-arm immune cells just like rugby players push off defenders from the other team.

16 Dec 2020

Study shows tRNA fragments play a key role in ischemic stroke

An ischemic stroke occurs when the homeostasis of the body and brain is highly disrupted. The immune system, among other things, activates an inflammatory response that can either overshoot or change into an immune deficiency.

14 Dec 2020