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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Personal genome sequencing and personalized medicine

Genetic mutations have given life on Earth a stunning variety of various sizes, colors, and shapes. Some changes are beneficial, while others are dangerous or ineffective. There are about 4.5 million genetic variants per individual.

31 Mar 2023

Immune cells in human blood produce acetylcholine that regulates blood pressure and inflammation

Acetylcholine regulates blood flow, but the source of blood acetylcholine has been unclear. Now, researchers at Karolinska Institutet have discovered that certain T cells in human blood can produce acetylcholine, which may help regulate blood pressure and inflammation.

31 Mar 2023

Harnessing a natural bacterial system to deliver proteins in mice and human cells

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have harnessed a natural bacterial system to develop a new protein delivery approach that works in human cells and animals.

30 Mar 2023

FDA-approved compound promotes photoreceptor survival in lab models of inherited retinal ciliopathy

A National Eye Institute-led team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10), an inherited retinal ciliopathy disease that often results in severe visual impairment or blindness in early childhood.

30 Mar 2023

Study expands understanding of PAK1-related IDDMSSD

A recent study from Texas Children's Hospital and Baylor College of Medicine has expanded the clinical spectrum of a new epileptic disorder called Intellectual Developmental Disorder with Macrocephaly, Seizures, and Speech Delay (IDDMSSD) with the identification of the first recurrently affected residue identified in the protein kinase domain of PAK1 protein.

30 Mar 2023

Additional therapeutic maneuver may be needed to stop some metastasized tumors Cancer That...

Cancer that has spread to areas like the lungs can apply the brakes to a natural pathway that should recruit killer T cells directly to where it has metastasized, scientists report.

29 Mar 2023

The proper implementation of stem cell-based disease models

Scientists have learned how to manufacture induced pluripotent stem cells (iPSC) from regular cells through genetic reprogramming during the last ten years.

29 Mar 2023

Beneficial microbes in the infant gut use nitrogen from human milk to support pediatric development

A University of Massachusetts Amherst nutrition scientist who has spent his career studying breast milk has demonstrated how beneficial microbes in the gut of infants use nitrogen from human milk to support pediatric nutrition and development.

28 Mar 2023

Myeloid cells contribute to a long-lived HIV reservoir, study shows

A subset of white blood cells, known as myeloid cells, can harbor HIV in people who have been virally suppressed for years on antiretroviral therapy, according to findings from a small study supported by the National Institutes of Health.

28 Mar 2023

Common Epstein-Barr virus may be a trigger for multiple sclerosis

In 1868, French physician Jean-Martin Charcot, known as the founder of modern neurology, defined a disease entity in which multiple plaques formed in the brain and spinal cord, with varying physical symptoms, called Sclérose en plaques, or in English as multiple sclerosis (MS).

24 Mar 2023

Learning how the brain makes choices could help better understand neurological disorders

New research published by investigators at Cedars-Sinai advances scientific understanding of how the brain weighs decisions involving what people like or value, such as choosing which book to read, which restaurant to pick for lunch-;or even, which slot machine to play in a casino.

24 Mar 2023

Eye color genes play important roles in maintaining retinal health

Metabolic pathways consist of a series of biochemical reactions in cells that convert a starting component into other products.

24 Mar 2023

Using AI to screen for genetic mutations in cancerous brain tumors in under 90 seconds

Using artificial intelligence, researchers have discovered how to screen for genetic mutations in cancerous brain tumors in under 90 seconds -; and possibly streamline the diagnosis and treatment of gliomas, a study suggests.

24 Mar 2023

Brain scans link signs of cellular aging to symptoms of Alzheimer’s

According to a new study led by Anya Topiwala of Oxford Population Health, a division of the University of Oxford in the United Kingdom, and published on March 22nd, 2023 in the open-access journal PLOS ONE, changes in the brain caused by Alzheimer’s disease are connected to telomeres shortening, the protective caps on the ends of chromosomes that shorten as cells age.

23 Mar 2023

New type of neural implant could restore limb function to amputees

Researchers have developed a new type of neural implant that could restore limb function to amputees and others who have lost the use of their arms or legs.

23 Mar 2023

Foods with a high fat and sugar content change our brain, shows study

Chocolate bars, crisps and fries - why can't we just ignore them in the supermarket? Researchers at the Max Planck Institute for Metabolism Research in Cologne, in collaboration with Yale University, have now shown that foods with a high fat and sugar content change our brain: If we regularly eat even small amounts of them, the brain learns to consume precisely these foods in the future.

23 Mar 2023

Brain News and Research

Personal genome sequencing and personalized medicine

Immune cells in human blood produce acetylcholine that regulates blood pressure and inflammation

Harnessing a natural bacterial system to deliver proteins in mice and human cells

FDA-approved compound promotes photoreceptor survival in lab models of inherited retinal ciliopathy

Study expands understanding of PAK1-related IDDMSSD

Additional therapeutic maneuver may be needed to stop some metastasized tumors Cancer That...

The proper implementation of stem cell-based disease models

Beneficial microbes in the infant gut use nitrogen from human milk to support pediatric development

Myeloid cells contribute to a long-lived HIV reservoir, study shows

Common Epstein-Barr virus may be a trigger for multiple sclerosis

Learning how the brain makes choices could help better understand neurological disorders

Eye color genes play important roles in maintaining retinal health

Using AI to screen for genetic mutations in cancerous brain tumors in under 90 seconds

Brain scans link signs of cellular aging to symptoms of Alzheimer’s

New type of neural implant could restore limb function to amputees

Foods with a high fat and sugar content change our brain, shows study

Wearable microscopes produce real-time images of mouse spinal cord activity

Study identifies 238 amyloid toxicity protective or activator genes

Deactivating mosquito sperm to control populations of Culex

Genetic signature might be shared across multiple substance use disorders, new study reveals

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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