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Harnessing a natural bacterial system to deliver proteins in mice and human cells

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have harnessed a natural bacterial system to develop a new protein delivery approach that works in human cells and animals.

30 Mar 2023

Single monoclonal antibody infusion can strengthen the body's fight against yellow fever

New research from Oregon Health & Science University and collaborators indicates lab-made antibodies may be able to cure people infected with yellow fever, a virus for which there is no treatment.

30 Mar 2023

COVID-19 vaccines boost the levels of T cells in immunocompromised hematology patients

Researchers found that, despite being heavily immunocompromised, hematology patients generate strong cellular immune responses against SARS-CoV-2 after vaccination, on par with that of healthy individuals.

30 Mar 2023

FDA-approved compound promotes photoreceptor survival in lab models of inherited retinal ciliopathy

A National Eye Institute-led team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10), an inherited retinal ciliopathy disease that often results in severe visual impairment or blindness in early childhood.

30 Mar 2023

Study reports a new target to fight against antibiotic-resistant pneumonia

Increases in multidrug-resistance in the bacteria Streptococcus pneumoniae have made it the fourth-leading cause of death associated with antibiotic resistance.

30 Mar 2023

Study expands understanding of PAK1-related IDDMSSD

A recent study from Texas Children's Hospital and Baylor College of Medicine has expanded the clinical spectrum of a new epileptic disorder called Intellectual Developmental Disorder with Macrocephaly, Seizures, and Speech Delay (IDDMSSD) with the identification of the first recurrently affected residue identified in the protein kinase domain of PAK1 protein.

30 Mar 2023

Using better probiotics to maintain a healthy gut microbiome

Bacteria have thousands of genes and functions that we, the human host, do not have. For instance, bacteria can help us digest fiber, provide support to our immune systems, and absorb important nutrients. But reaping the benefits of "good bacteria" is easier said than done.

29 Mar 2023

New project addresses the lack of standards for optimal management of Lp(a)

According to a recent scientific statement gathered from American Heart Association, high levels of lipoprotein(a) [Lp(a)] are known to be a separate, chiefly inherited and causal risk factor for cardiovascular disease, known to be the leading cause of death and disability around the world.

29 Mar 2023

Researchers develop a novel probe for selectively dyeing M1 and M2 macrophages

M1 and M2 are activated macrophages that protect our immune system and maintain homeostasis.

28 Mar 2023

Beneficial microbes in the infant gut use nitrogen from human milk to support pediatric development

A University of Massachusetts Amherst nutrition scientist who has spent his career studying breast milk has demonstrated how beneficial microbes in the gut of infants use nitrogen from human milk to support pediatric nutrition and development.

28 Mar 2023

Myeloid cells contribute to a long-lived HIV reservoir, study shows

A subset of white blood cells, known as myeloid cells, can harbor HIV in people who have been virally suppressed for years on antiretroviral therapy, according to findings from a small study supported by the National Institutes of Health.

28 Mar 2023

Thickness of cancer cells' glycocalyx barrier determines immune cell evasion of tumors

One of the ways that cancer cells hide from the body's immune system is by forming a thin surface barrier called the glycocalyx.

27 Mar 2023

Heart-healthy benefits of walnuts may be linked to beneficial changes in the mix of gut microbes

A new study examining the gene expression of gut microbes suggests that the heart-healthy benefits of walnuts may be linked to beneficial changes in the mix of microbes found in our gut.

27 Mar 2023

Innovative new approach to constructing a nose in young patients with arhinia

Congenital arhinia (meaning patients born without a nose) is a rare condition associated with high mortality if not identified.

24 Mar 2023

Generating functional patient-specific thymic organoids from human pluripotent stem cells

Researchers have used pluripotent stem cells to make thymus organoids that support the development of patient-specific T-cells, researchers report March 23rd in the journal Stem Cell Reports.

24 Mar 2023

Digital Science releases an analysis of the global research response to climate change and zoonotic diseases

Whether it's diseases from bats, birds, pigs, or mosquitoes, climate change brings with it an increased risk of animal-borne (or "zoonotic") diseases that can transmit to humans.

24 Mar 2023

Common Epstein-Barr virus may be a trigger for multiple sclerosis

In 1868, French physician Jean-Martin Charcot, known as the founder of modern neurology, defined a disease entity in which multiple plaques formed in the brain and spinal cord, with varying physical symptoms, called Sclérose en plaques, or in English as multiple sclerosis (MS).

24 Mar 2023

Clinical News and Research

Harnessing a natural bacterial system to deliver proteins in mice and human cells

Single monoclonal antibody infusion can strengthen the body's fight against yellow fever

COVID-19 vaccines boost the levels of T cells in immunocompromised hematology patients

FDA-approved compound promotes photoreceptor survival in lab models of inherited retinal ciliopathy

Study reports a new target to fight against antibiotic-resistant pneumonia

Study expands understanding of PAK1-related IDDMSSD

Using better probiotics to maintain a healthy gut microbiome

New project addresses the lack of standards for optimal management of Lp(a)

Researchers develop a novel probe for selectively dyeing M1 and M2 macrophages

Beneficial microbes in the infant gut use nitrogen from human milk to support pediatric development

Myeloid cells contribute to a long-lived HIV reservoir, study shows

Thickness of cancer cells' glycocalyx barrier determines immune cell evasion of tumors

Heart-healthy benefits of walnuts may be linked to beneficial changes in the mix of gut microbes

Innovative new approach to constructing a nose in young patients with arhinia

Generating functional patient-specific thymic organoids from human pluripotent stem cells

Digital Science releases an analysis of the global research response to climate change and zoonotic diseases

Common Epstein-Barr virus may be a trigger for multiple sclerosis

Using AI to screen for genetic mutations in cancerous brain tumors in under 90 seconds

New type of neural implant could restore limb function to amputees

Blunted inflammatory response in obese individuals responsible for susceptibility to severe COVID-19

Driving Support for Pharmaceutical Testing Through Continuous Innovation

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Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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