Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Markers Indicating Early Signs of Schizophrenia Identified

For the first time, a global study group headed by investigators at Virginia Commonwealth University has found markers that might point out early if a person is susceptible to schizophrenia in the early stage itself.

28 Apr 2023

A Rapid Method for the Quantitative Detection of miRNA

Researchers investigating the growth of a roundworm discovered a tiny RNA molecule that controlled the expression of specific genes in the early 1990s. This resulted in the discovery of microRNAs (miRNAs), which are now known to exist in all forms of life. These molecules, it turns out, play vital functions in a variety of biological processes.

26 Apr 2023

Scientists Illuminate the Mechanism that Raises and Lowers PSMA Expression in Prostate Cancer

Like the better-known prostate-specific antigen (PSA), prostate-specific membrane antigen (PSMA) is a biomarker that can tell physicians much about a patient's metastatic prostate cancer.

11 Apr 2023

Immunotherapy Response in Advanced Melanoma: Effect of Previous Treatments

According to a study conducted by UCLA, patients with advanced melanoma responded differently to PD-1 checkpoint blockade immunotherapy depending on a variety of variables, including whether or not they had previously received CTLA-4 blockade, another type of immunotherapy.

11 Apr 2023

Retinal Microvasculature may be a Potential Biological Indicator for Predicting Acute Mountain Sickness

This study is led by Dr.Ningli Wang and Dr.Yuan Xie (Beijing Tongren Hospital, Capital Medical University), they provide evidence that retinal microvasculature is a potential biomarker for cerebral microvasculature changes and acute mountain sickness(AMS) development during risk assessment of individuals at high altitudes.

10 Apr 2023

Novel Genes Could Serve as Predictive Biomarkers for PARP Inhibitor Response in Prostate Cancer

Prostate cancer tumors harboring BRCA1/2 mutations are exceptionally sensitive to PARP inhibitors, while genomic alterations in other DNA damage response (DDR) genes are less responsive.

5 Apr 2023

Epigenetic fingerprinting helps trace the origin of animal products

Food analysis laboratories can provide an answer to questions like “Was the salmon for dinner really caught wild or did it come from aquaculture? What to make of the alleged ‘biolabel quality’ of the shrimp for the seafood salad? And was the chicken for the Sunday roast really allowed to spend its life in the open air?” to a limited extent.

30 Mar 2023

Scientists devise a tiny, nano-sized sensor capable of detecting protein biomarkers

While a popular hobby for many, fishing is also a pastime full of uncertainty. Each time you have something on the line, you can never be completely sure what type of fish you've hooked until you pull it out of the water.

21 Mar 2023

Study: Oral verapamil improves the pancreas' insulin secretion in children with newly-diagnosed TID

Published in JAMA, a University of Minnesota led study shows that verapamil, a drug commonly used to treat high blood pressure and heart conditions, can have a beneficial effect on the pancreas in children with newly-diagnosed type 1 diabetes (T1D).

27 Feb 2023

New biomarker helps identify biological age

Once considered to be incompetent in encoding proteins due to their simple monotonous DNA repetitions, tiny telomeres at the tips of human chromosomes now appear to have a powerful biological function that could help better understand cancer and aging.

21 Feb 2023

New approach to rapidly determine biological aging

Telomeres-;the caps at the ends of chromosomes that protect our genetic materials from the brunt of cellular wear and tear-;are known to shorten and fray over time.

16 Feb 2023

The essential protein needed for immune evasion and tumor cell metabolism

Typically, tumor cells change their energy metabolism and take in more glucose to enable their rapid division and spread. As a result, the body’s immune response to cancer is suppressed by limiting the immune cells’ access to glucose.

15 Feb 2023

Prolonged alcohol use and its detrimental effects on blood protein snapshot

Jon Jacobs, a biochemist, has examined the blood of people suffering from diseases including Ebola, cancer, TB, hepatitis, diabetes, Lyme disease, brain damage, and influenza.

10 Feb 2023

Combination of two types of immune cells helps predict response to cancer immunotherapy

Thanks to a new prognostic method for detecting cancers including cancer of the large intestine, doctors could provide clearer disease prognoses and predict which patients will respond best to immunotherapy.

10 Feb 2023

Strata Oncology publishes study validating integrative pan-solid tumor predictor of PD-1/PD-L1 blockade benefit

Strata Oncology, Inc., a next-generation precision oncology company enabling smarter and earlier cancer treatment, today announced the publication of a new peer-reviewed study validating the clinical utility of the company's proprietary pan-solid tumor predictive biomarker for anti-PD-1/PD-L1 checkpoint inhibitor monotherapy benefit, Immunotherapy Response Score (IRS).

8 Feb 2023

Biomarker News and Research

Markers Indicating Early Signs of Schizophrenia Identified

A Rapid Method for the Quantitative Detection of miRNA

Scientists Illuminate the Mechanism that Raises and Lowers PSMA Expression in Prostate Cancer

Immunotherapy Response in Advanced Melanoma: Effect of Previous Treatments

Retinal Microvasculature may be a Potential Biological Indicator for Predicting Acute Mountain Sickness

Novel Genes Could Serve as Predictive Biomarkers for PARP Inhibitor Response in Prostate Cancer

Epigenetic fingerprinting helps trace the origin of animal products

Scientists devise a tiny, nano-sized sensor capable of detecting protein biomarkers

Study: Oral verapamil improves the pancreas' insulin secretion in children with newly-diagnosed TID

New biomarker helps identify biological age

New approach to rapidly determine biological aging

The essential protein needed for immune evasion and tumor cell metabolism

Prolonged alcohol use and its detrimental effects on blood protein snapshot

Combination of two types of immune cells helps predict response to cancer immunotherapy

Strata Oncology publishes study validating integrative pan-solid tumor predictor of PD-1/PD-L1 blockade benefit

Persistent tumor mutation load may help predict outcome of novel immunotherapies

Novel blood biomarker predicts a favorable response to CART cell therapy

Emerging viruses could be easily detected with a simple nasal swab

Gyros Protein Technologies adds Gyrolab® Biomarker Kits to expand range of ready-to-use kits and reagents

New study figures out which patients will react to immunotherapy

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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