Cell Signaling News and Research

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Cell signaling is vital for cells to communicate and coordinate their activities, not just in the human body, but in all organisms. There are thousands of signaling pathways, ranging from protein homeostasis to carcinogenesis and biofilm formation.

Researchers explore the regulatory role of protein in human health and disease

Researchers from the University of Virginia, Lehigh University and the Massachusetts Institute of Technology are pooling their respective labs' expertise to unlock the mysteries of a protein that plays a critical regulatory role in human health and disease.

5 Feb 2021

Synthetic biomolecule resembles dual stimuli-responsive channel

For the first time, researchers from the Tokyo Institute of Technology (Tokyo Tech) and the University of Tokyo in Japan have produced a new artificial transmembrane ion channel—based on a naturally found transmembrane channel that plays a role in neuron signaling—that reacts to both electrical and chemical stimuli.

2 Feb 2021

New class of protein materials can influence cell signaling

A new study has revealed that a novel class of protein material that communicates with living cells without being absorbed by them can affect cell signaling. The protein material does this by attaching and sequestering cell surface receptors.

7 Jan 2021

Microbe found in the colon may promote breast cancers

A microbe found in the colon and commonly associated with the development of colitis and colon cancer also may play a role in the development of some breast cancers, according to new research from investigators with the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

7 Jan 2021

Combination method can boost immunotherapy for breast cancer

According to a new study performed by scientists from the University of North Carolina, stimulating an immune signaling pathway, which is best known for combating bacterial and viral infections, can increase the potential of genetically engineered T cells to remove breast cancer in mice.

4 Jan 2021

Immune cell biomarker may help identify patients at risk for graft-versus-host disease

A recent report published in Science Translational Medicine by MUSC Hollings Cancer Center investigator Sophie Paczesny, M.D., Ph.D., sheds light on immune cell biomarkers that may reveal which patients are most at risk for graft-versus-host disease (GVHD), a life-threatening condition that can arise after hematopoietic stem cell transplantation (HSCT) for treatment of liquid cancers such as leukemia.

8 Oct 2020

Researchers identify specific cellular pathway involved in the regeneration of lung tissue

Scientists have discovered a new cellular pathway that can be targeted with a naturally occurring medication to activate the regeneration of lung tissue.

30 Sep 2020

Researchers unravel the molecular basis underlying colorectal cancer

A team of scientists has unraveled the molecular mechanism behind one of the causes of colorectal cancer, and a treatment target.

15 Sep 2020

Researchers review the role of macrophage activation syndrome in COVID-19

A major percentage of COVID-19 cases have become so severe that hospital admissions have become mandatory for both monitoring and treatment.

10 Sep 2020

Study reveals why immunity boost from seasonal flu vaccines is not long lasting

A study from Emory Vaccine Center provides insights into why the boost in immunity from seasonal flu vaccination lasts for months but not years, unlike some childhood vaccinations.

14 Aug 2020

Deep Learning On Cell Signaling Networks Establishes AI For Single-Cell Biology

Computer systems that emulate key aspects of human problem solving are commonly referred to as AI. This field has seen massive progress over the last years.

6 Aug 2020

New method reveals the dynamics of cell development and gene activity

Studies on cellular dynamics are vital to interpret the development of cells and the progression of various diseases.

5 Aug 2020

Researchers identify phosphoprotein biomarkers to guide cancer therapy

Precision medicine in cancer treatment uses genetic changes in the cancer cells to select the best therapies for individual patients.

29 Jul 2020

Study shows efficacy of L-Grb2 in preclinical models of ovarian and uterine cancer

The cover for issue 29 of Oncotarget features Figure 5, "In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model," by Lara, et al. which reported that adaptor proteins such as growth factor receptor-bound protein-2 play important roles in cancer cell signaling.

23 Jul 2020