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Researchers identify a set of sporadic genetic mutations behind rare brain malformations

A rare type of brain blood vessel malformation known as a cavernous angioma affects more than one million Americans and carries a lifetime risk of stroke and seizures.

31 Mar 2022

HIF-1alpha inhibitor preserves the activity of insulin-producing beta cells in diabetic mice

High blood glucose is responsible for several complications in type 1 and type 2 diabetes. Researchers at Karolinska Institutet in Sweden have identified a new antidiabetic substance that preserves the activity of insulin-producing beta cells and prevents high blood glucose in mice.

31 Mar 2022

Killifish study finds age-dependent loss of antibody diversity

As we age, our immune system works less well. We become more susceptible to infections and vaccinations no longer work as effectively.

29 Mar 2022

Researchers reveal how deleting a protein could prevent heart attacks and strokes

Macrophages travel through our arteries, gobbling fat the way Pac-man gobbled ghosts. But fat-filled macrophages can narrow blood vessels and cause heart disease.

29 Mar 2022

Study reveals genetically driven mucus pathobiology in asthma

A significant amount of genetic risk for asthma is likely mediated through altered gene expression within the airway epithelium.

29 Mar 2022

New approach to assess motility and invasive capacity of cancer cells in a tissue section

There are many proteins involved in the spread of cancer. However, some of them are notably difficult to observe in patient tissue samples.

28 Mar 2022

Study reveals why infected individuals cannot get rid of HIV altogether

Thanks to antiretroviral therapy, HIV infection is no longer the life sentence it once was. But despite the effectiveness of drugs to manage and treat the virus, it can never be fully eliminated from the human body, lingering in some cells deep in different human tissues where it goes unnoticed by the immune system.

28 Mar 2022

Novel protein Atossa regulates cell invasion

Researchers from the Institute of Science and Technology Austria have found a novel protein that stimulates energy generation inside immune cells, allowing them to penetrate more effectively.

24 Mar 2022

Researchers study how trypanosomes change the predatory bug’s intestinal microbiota

In Central and South America, predatory blood-sucking bugs transmit the causative agent of the widely prevalent Chagas disease.

22 Mar 2022

Research reveals how a marine bacterium makes a potent anti-cancer molecule

Years of toil in the laboratory have revealed how a marine bacterium makes a potent anti-cancer molecule.

22 Mar 2022

Transcriptomic analysis of Alzheimer's patients reveals early organelle dysfunction in astrocytes

An international group of researchers led by the UAB analyzed the genes that are expressed in neurons and astrocytes based on data from 800 individuals and compared what happens in Alzheimer's patients and in people without diagnosed dementia.

21 Mar 2022

Proteins surrounding organs and tissues switch off natural killer cells’ “killer” function, study finds

Natural killer (NK) cells, which are part of the body’s innate, or first-line, immune response, interact with tumor cells, viral infections, and solid organ transplants, according to a new study.

21 Mar 2022

Research highlights how genome editing tool CRISPR knocks off genes in cancer cells

Researchers have created a novel method that allows them to correlate particular genes to complex tumor properties at a size and resolution that has never been achievable.

21 Mar 2022

ISU researchers receive major funding to go forward on blood stem cells research

For years, scientists have been unable to create a patient’s blood cells to cure blood illnesses, but a recently implemented federal funding might help IOWA State University researchers take important steps toward making that prospect a reality.

21 Mar 2022

Researchers demonstrate how sperms defend their membranes from oxidation

A team of researchers compared lipid profiles of sperm to learn more about their vulnerability to harmful oxidation and antioxidant capacity in different species’ semen.

21 Mar 2022

Study shows how immune systems tune antibodies to fight against infection

University of Alberta researchers have discovered new knowledge on a cellular process in the immune system.

21 Mar 2022

Researchers develop an antibody as a tool for opening the blood-brain barrier

The brain is composed of billions of neurons-; vulnerable cells that require a protective environment to function properly.

17 Mar 2022

Immunity to the SARS-CoV-2 virus likely to protect against omicron

People who developed immunity to SARS-CoV-2, either by vaccination or contact, are expected to get some protection against the pathogen’s omicron version.

16 Mar 2022

INTEGRA’s VIAFLO 384 proves indispensable in neurodegeneration research

Scientists at Rejuveron Vascular Therapeutics AG, a company specializing in the development of therapies to tackle neurodegeneration, are using INTEGRA’s VIAFLO 384 handheld electronic pipette to accelerate their research.

From INTEGRA Biosciences 16 Mar 2022

Macrophages show altered inflammatory, metabolic expression months after mild COVID-19

There is a lack of understanding as to why some people suffer from long-lasting symptoms after COVID-19 infection.

15 Mar 2022

Blood News and Research

Researchers identify a set of sporadic genetic mutations behind rare brain malformations

HIF-1alpha inhibitor preserves the activity of insulin-producing beta cells in diabetic mice

Killifish study finds age-dependent loss of antibody diversity

Researchers reveal how deleting a protein could prevent heart attacks and strokes

Study reveals genetically driven mucus pathobiology in asthma

New approach to assess motility and invasive capacity of cancer cells in a tissue section

Study reveals why infected individuals cannot get rid of HIV altogether

Novel protein Atossa regulates cell invasion

Researchers study how trypanosomes change the predatory bug’s intestinal microbiota

Research reveals how a marine bacterium makes a potent anti-cancer molecule

Transcriptomic analysis of Alzheimer's patients reveals early organelle dysfunction in astrocytes

Proteins surrounding organs and tissues switch off natural killer cells’ “killer” function, study finds

Research highlights how genome editing tool CRISPR knocks off genes in cancer cells

ISU researchers receive major funding to go forward on blood stem cells research

Researchers demonstrate how sperms defend their membranes from oxidation

Study shows how immune systems tune antibodies to fight against infection

Researchers develop an antibody as a tool for opening the blood-brain barrier

Immunity to the SARS-CoV-2 virus likely to protect against omicron

INTEGRA’s VIAFLO 384 proves indispensable in neurodegeneration research

Macrophages show altered inflammatory, metabolic expression months after mild COVID-19

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