Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Genes linked to Down syndrome abnormalities may offer protection against solid tumors

Scientists from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago discovered that a set of genes with decreased expression in individuals with Down syndrome may lead to clinical abnormalities in this population, such as poor muscle development and heart valve problems.

6 Aug 2020

Epigenetics key to daily production of 10 billion blood cells without mistakes

Just one in 2,000 bone marrow cells are hematopoietic stem cells (HSC), but these are the source of the ten billion blood cells humans make every day.

6 Aug 2020

Deep Learning On Cell Signaling Networks Establishes AI For Single-Cell Biology

Computer systems that emulate key aspects of human problem solving are commonly referred to as AI. This field has seen massive progress over the last years.

6 Aug 2020

New findings help to better understand the genetics of neuropsychiatric disorders

A new study led by NorthShore University HealthSystem (NorthShore) and the University of Chicago took a novel approach to identifying SNPs influencing the risk of neuropsychiatric disorders like schizophrenia, bipolar and major depressive disorder, the institutions announced today.

5 Aug 2020

Hudsonalpha researchers help elucidate functional elements of the genome

Although the Human Genome Project sequenced a nearly-complete human genome almost 20 years ago, only about two percent of the genes in the human genome have been extensively studied and identified as protein-coding genes. Proteins form the basis of living tissues and play a central role in biological processes.

3 Aug 2020

New methods to regulate enzymes involved in SARS-CoV-2 virus infection

A research team from the HSE University has designed innovative methods for controlling the expression of TMPRSS2 and ACE2 enzymes.

30 Jul 2020

New tool predicts and identifies novel genes involved in various biological processes

Chromatin plays a significant role in the silencing and activation of gene transcription, and establish the fate of the cells during development.

30 Jul 2020

Commercial pesticides can help improve crop safety

Researchers have revealed that commercial pesticides can be applied to crops in the Cucurbitaceae family to decrease their accumulation of hydrophobic pollutants, thereby improving crop safety.

29 Jul 2020

Movement of small RNAs underlies mobile RNA interference

Biologists have known for some time that RNA interference can silence genes in far-off cells. They suspected that a messenger substance “transmits” RNA interference.

29 Jul 2020

Supercomputer analyses point to a new pathway for COVID-19 inflammatory response

Analyses of lung fluid cells from COVID-19 patients conducted on a supercomputer point to patterns that may explain the body's response to SARS-CoV-2.

29 Jul 2020

Discovering the Critical Role of Astrocytes in Neurodegenerative Diseases

AZoLifeSciences talks to Dr. Shane Liddelow about their research into discovering the critical role of astrocytes in neurodegenerative diseases like glaucoma.

From New York University (NYU) 29 Jul 2020

Deep learning algorithm can infer molecular alterations in cancer from histology images

Researchers at the University of Chicago Medicine Comprehensive Cancer Center, working with colleagues in Europe, created a deep learning algorithm that can infer molecular alterations directly from routine histology images across multiple common tumor types.

29 Jul 2020

Human genome may explain the neonatal origins of immune and inflammatory diseases

A study published in the journal Nature Communications has pinpointed a number of areas of the human genome that may help explain the neonatal origins of chronic immune and inflammatory diseases of later life, including type 1 diabetes, rheumatoid arthritis and coeliac disease.

29 Jul 2020

EBV viral genome modifies the host epigenetic landscape to promote gastric cancer

The Epstein-Barr virus (EBV), one of the most common human viruses, is associated with about 8-10 per cent of stomach -- or gastric -- cancers, the third leading cause of cancer death globally.

28 Jul 2020

Computational tool can help study APA mechanism that regulates gene expression

Scientists keen on solving the regulation of genes implicated in human health and disease are widening their horizons by closely APA.

27 Jul 2020

Study shows how cancer develops resistance to chemotherapy

Cancer's knack for developing resistance to chemotherapy has long been a major obstacle to achieving lasting remissions or cures. While tumors may shrink soon after chemotherapy, many times they eventually grow back.

24 Jul 2020

Study shows efficacy of L-Grb2 in preclinical models of ovarian and uterine cancer

The cover for issue 29 of Oncotarget features Figure 5, "In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model," by Lara, et al. which reported that adaptor proteins such as growth factor receptor-bound protein-2 play important roles in cancer cell signaling.

23 Jul 2020

Researchers identify a potential biomarker of aging

The skin is the only organ that shows age more profoundly. While researchers have hypothesized about the ravages of time on skin and also the epidermal stem cells that undergo differentiation to restore the external layer of the skin, no suitable method is available to assess their aging at the molecular level.

22 Jul 2020

Researchers comprehensively describe the 'human tissue virome atlas'

Human-resident microbes can influence both health and disease. Investigating the microbiome using next-generation sequencing technology has revealed examples of mutualism and conflict between microbes and humans.

22 Jul 2020

Study explores the genetic and molecular basis of PD-L2 regulation

In immune-related disorders, therapy often involves identifying the molecules responsible for immune dysregulation and targeting them using drugs.

22 Jul 2020

Gene Expression News and Research

Further Reading

Genes linked to Down syndrome abnormalities may offer protection against solid tumors

Epigenetics key to daily production of 10 billion blood cells without mistakes

Deep Learning On Cell Signaling Networks Establishes AI For Single-Cell Biology

New findings help to better understand the genetics of neuropsychiatric disorders

Hudsonalpha researchers help elucidate functional elements of the genome

New methods to regulate enzymes involved in SARS-CoV-2 virus infection

New tool predicts and identifies novel genes involved in various biological processes

Commercial pesticides can help improve crop safety

Movement of small RNAs underlies mobile RNA interference

Supercomputer analyses point to a new pathway for COVID-19 inflammatory response

Discovering the Critical Role of Astrocytes in Neurodegenerative Diseases

Deep learning algorithm can infer molecular alterations in cancer from histology images

Human genome may explain the neonatal origins of immune and inflammatory diseases

EBV viral genome modifies the host epigenetic landscape to promote gastric cancer

Computational tool can help study APA mechanism that regulates gene expression

Study shows how cancer develops resistance to chemotherapy

Study shows efficacy of L-Grb2 in preclinical models of ovarian and uterine cancer

Researchers identify a potential biomarker of aging

Researchers comprehensively describe the 'human tissue virome atlas'

Study explores the genetic and molecular basis of PD-L2 regulation

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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