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Scientists determine first 3D structure of COVID-19 main protease

A team of Chinese scientists has reported the high-resolution crystal structure of the main protease (Mpro) of the COVID-19 virus and has identified drugs that may hold promise in combating the virus.

15 Apr 2020

Role of VRAC ion channel in fight against virus infections

VRAC/LRRC8 chloride channels play a crucial role in the transport of neurotransmitters, amino acids, and cytostatics.

14 Apr 2020

Study reveals new mechanism that controls chromosome inheritance

During the process of each single cell division, the chromosomal genetic data should be uniformly distributed between the freshly developing daughter cells.

13 Apr 2020

New study on proteins advances basic understanding of human life

A minute chemical modification on one of the most copious and vital proteins in cells—actin—has been a mystery as its function is not fully known.

9 Apr 2020

Researchers use ultrasensitive protein detection method to evaluate embryo quality

Infertility is estimated to affect 9% of reproductive-aged couples globally, and many couples consequently turn to assisted reproductive technology.

8 Apr 2020

Enhancing DNA repair could help improve agronomic traits in multiple crops

A new genome editing system enhances the efficiency of an error-free DNA repair pathway, which could help improve agronomic traits in multiple crops.

8 Apr 2020

Physical properties of extracellular bacterial membrane vesicles are significantly diverse

According to a new study by researchers from Kanazawa University and Tsukuba University, which was reported in Nanoscale, the physical properties of extracellular bacterial membrane vesicles are considerably varied.

8 Apr 2020

Study reveals shape-shifting enzyme dihydrofolate reductase is associated with catalysis

Researchers from the University of Groningen have visualized the characteristics of a single enzyme within a nanopore.

8 Apr 2020

Scientists Discover Gene That Increases Risk Of Alzheimer's Disease

Researchers from UBC and the Central South University (CSU) in China have for the first time identified a gene that increases the risk of Alzheimer's disease.

2 Apr 2020

Hidden Messages In Protein Blueprints

Scientists from DKFZ, HI-STEM have identified a new control mechanism that enables stem cells to adapt their activity in emergency situations.

2 Apr 2020

Study discovers hydrogen cycling in the Acetobacterium woodii bacterium

At Goethe University Frankfurt, microbiologists have unraveled the mechanism of hydrogen use by the bacterium Acetobacterium woodii for energy conservation.

31 Mar 2020

Researchers develop a modular system for genetic reprogramming of bacteria

Novel biomaterials could soon be created using magnetic bacteria.

26 Mar 2020

Do Pancreatic Cells Write Their Own Autoimmune Ending?

Researchers have discovered that pancreatic cells, producing lipids, can create their own autoimmune ending. This article looks at how this is possible.

25 Mar 2020

Genetically manipulating cells using synthetic materials to construct artificial structures

Researchers at the Stanford School of Engineering have designed a technique for reprogramming cells to use synthetic materials, which the team provides, to create artificial structures that can perform functions within the body.

20 Mar 2020

Bacteria’s ability to develop novel peptides for cancer treatment

At Texas A&M University, chemists have identified a new way to beat viruses at their own game—take a p[h]age from bacteria’s playbook and, in the process, develop new kinds of drugs to combat cancer and a range of other human diseases.

20 Mar 2020

Study discovers structure of bacterial enzyme that breaks down amino acid found in collagen

Chemists from MIT and Harvard University have elucidated the structure of a strange bacterial enzyme with the ability to break down an amino acid found in collagen.

18 Mar 2020

New CRISPR technology targets thousands of genes

Thanks to CRISPR-based genetic screens, researchers were able to detect genes that play a major role in lung cancer metastasis, cancer immunotherapy, sickle-cell anemia, and a host of other medical disorders.

18 Mar 2020

More efficient, cost-effective method for accurate synthesis of DNA

DNA is a genetic material that continues to survive only through replication, either naturally or synthetically. Humans require reproduction of DNA to replace damaged or old cells, but the potential to replicate DNA in a laboratory setting can allow scientists understand the disease mechanisms or the platform to develop treatments.

17 Mar 2020

Copper-binding protein influences migration of breast cancer cells

At the Chalmers University of Technology, scientists have demonstrated that the Atox1 protein, which is highly concentrated in breast cancer cells, takes part in a process—the process through which cancer cells spread.

11 Mar 2020