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Rare and protective loss-of-function mutations offer possible NAFLD drug targets

A significant genome-wide association study on the nonalcoholic fatty liver disease (NAFLD) has just been published in Nature Genetics by researchers from Amgen subsidiary deCODE Genetics.

26 Oct 2022

NATA accreditation for BGI Australia to perform whole exome sequencing

The National Association of Testing Authorities (NATA) has accredited BGI Australia’s lab to conduct clinical Whole Exome Sequencing in Australia, opening the door for the multinational life sciences company to offer clinical sequencing services for locating potential disease-causing genetic changes.

25 Oct 2022

Genome Editing Has A New Code

In this interview, we speak to Samantha Maragh, the leader of the genome editing program at NIST, about the genome editing vocabulary and what this means for researchers worldwide.

From National Institute of Standards and Technology (NIST) 21 Oct 2022

All normal human tissues express remnants of widespread retrovirus

Ancient viral remnants in the human genome are active in both healthy and diseased tissues, restricting their applicability as disease indicators, according to a study published on October 18th, 2022, in the open access journal PLOS Biology by Aidan Burn at Tufts University in Boston, USA and colleagues.

20 Oct 2022

The mechanism behind the satiating effect of milk protein

Quark and cheese are primarily casein-based in terms of protein content. The stomach’s digestion of casein results in the production of protein fragments (peptides) that have an unpleasant flavor, despite casein itself not having a bitter flavor.

13 Oct 2022

New approach to identify cancerous tissue for surgical removal

It is crucial to distinguish between tumors and healthy tissues during cancer surgery. Fluorescent markers can assist in this process by improving tumor contrast during surgery.

13 Oct 2022

A more efficient way to deliver gene therapies to the CNS

For gene therapy, the blood-brain barrier (BBB) poses a formidable obstacle. The BBB, which is made up of cells that are closely packed together, prevents poisons and pathogens from accessing brain tissue while also blocking potential treatments for diseases that impact the CNS.

12 Oct 2022

Discovery and characterization of a new antifungal compound

Antimicrobial resistance has prompted scientists to search for novel compounds everywhere. A multinational group of European scientists reports the discovery of solanimycin, a novel antifungal antibiotic.

12 Oct 2022

Adults with congenital blindness experience striking recoveries of night vision after gene therapy

Adults with a genetic form of childhood-onset blindness experienced striking recoveries of night vision within days of receiving an experimental gene therapy, according to researchers at the Scheie Eye Institute in the Perelman School of Medicine at the University of Pennsylvania.

11 Oct 2022

UC Davis launches new center to accelerate the development of promising cancer therapies

UC Davis Comprehensive Cancer Center has launched a Center for Experimental Therapeutics in Cancer to accelerate promising cancer therapies from the lab to the bedside.

From The University of California, Davis 10 Oct 2022

Broadening the scope of CRISPR-Cas9 genome editing systems

A group of Northwestern University researchers has created a novel gene editing platform that might influence the future application of a nearly infinite library of CRISPR-based therapeutics.

7 Oct 2022

Genomic research helps in tackling the fatal complications of fungal infections

An important genetic discovery made by a research team led by a University of Massachusetts Amherst scientist sheds new light on the application of the drug caspofungin to treat the deadly fungal infection Aspergillus fumigatus, which claims the lives of about 100,000 severely immunocompromised individuals every year.

7 Oct 2022

A remarkable finding reorients attempts to cure liver disease

A long-running debate in gastroenterology has been settled by WEHI researchers who have shown that prevalent liver diseases are not caused by inflammatory cell death as previously believed.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 7 Oct 2022

Interactional closeness with a dog can increase prefrontal brain activity

Researchers led by Rahel Marti at the University of Basel in Switzerland report that viewing, feeling, and touching real dogs leads to increasingly higher levels of activity in the prefrontal cortex of the brain.

6 Oct 2022

New insight into human genome evolution

Researchers discovered that in one out of every 4,000 births, some of the genetic code from the mitochondria—the “batteries” that power human cells—inserts itself into the DNA, giving a startling new insight into how humans evolve.

6 Oct 2022

Novel molecules alleviate pain, avoid sedating effect

According to new research headed by UC San Francisco scientists, a newly found group of molecules relieved pain in mice whilst preventing the sedating effect that limits the usage of opiates.

3 Oct 2022

Transforming “tissue engineering” into a reality

The National Institute of Biomedical Imaging and Bioengineering awarded Case Western Reserve $6.1 million to develop body tissue engineering.

29 Sep 2022

WEHI receives $2.5 million fund to develop personalized cancer treatments

With a $2.5 million fund received from the Medical Research Future Fund (MRFF), a new genomics project led by WEHI will develop precision medicine and customized cancer therapy for Australians.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 27 Sep 2022

Tiny DNA strand net in a low-cost test platform traps COVID-19 virus

According to a new study, tiny nets made of DNA strands can capture the spike protein of the virus that causes COVID-19, illuminating it for a quick yet accurate diagnostic test and preventing it from infecting cells, suggesting a new potential path to antiviral treatment.

26 Sep 2022

Rumen-protected lysine improves uterine health

Boosting milk yield when included in the diet at sufficient levels, lysine is an important amino acid for dairy cows. But how could lysine be advantageous for cows in other means? A new study by the University of Illinois reveals that rumen-protected lysine can enhance uterine health if given in the transition period.

20 Sep 2022