Gene Editing News and Research

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Novel tool for genome-wide design, evaluation of gRNA sequences for CRISPR experiments

Commercially viable biofuel crops are vital to reducing greenhouse gas emissions, and a new tool developed by the Center for Advanced Bioenergy and Bioproducts Innovation should accelerate their development -; as well as genetic editing advances overall.

18 Feb 2022

CRISPR/Cas9-mediated gene editing is now feasible in ticks

Researchers have successfully used CRISPR-Cas9 to edit the genomes of the black-legged tick. To accomplish this feat, they developed an embryo injection protocol that overcame a major barrier in the field.

17 Feb 2022

UCI biologists discover how a gene variant protects against Alzheimer's disease

While the word "mutation" may conjure up alarming notions, a mutation in brain immune cells serves a positive role in protecting people against Alzheimer's disease.

15 Feb 2022

Gene-editing techniques could be used to tackle mitochondrial disorders, study shows

Defective mitochondria – the 'batteries' that power the cells of our bodies – could in future be repaired using gene-editing techniques.

9 Feb 2022

Scientists use CRISPRa to discover genes that play a role in immune cell biology

CRISPR genome editing has served as a powerful tool for deleting or altering DNA sequences and studying the resulting effect.

4 Feb 2022

Researchers identify new potential drug target that may block SARS-CoV-2 infection

In the quest for new treatments for COVID-19, a team led by researchers at UC San Francisco has identified a new potential drug target that may block infection by SARS-CoV-2. The protein, called BRD2, regulates the ACE2 receptor, which the novel coronavirus relies on to gain entry to its host's cells.

17 Jan 2022

Experts develop CRISPR-Cas9-mediated inheritance control in male mice

The world’s first CRISPR-Cas9 genetic editing-based strategy to regulate inheritance in mammals was declared nearly three years ago.

From UC San Diego 13 Jan 2022

Cryo-ET reveals mechanisms underlying gene mutations that lead to blindness

Researchers have discovered the structural determinants of the highly specialized rod outer segments membrane architecture of the eye, which plays a crucial role in vision.

7 Jan 2022

Experts develop Immuno-CRISPR assay to detect kidney transplant complications

Doctors monitor kidney transplant recipients for signs of rejection in several ways, including biopsy.

7 Jan 2022

Researchers fine-tune an additional system for more efficient gene editing

Over the past decade, the CRISPR genome-editing system has revolutionized molecular biology, giving scientists the ability to alter genes inside living cells for research or medical applications. Now, researchers at Gladstone Institutes have fine-tuned an additional system for more efficient gene editing, using molecules called retrons.

6 Jan 2022

Researchers use CRISPR-Cas9 to successfully target brown fat

Fat is an essential component of life, however too much fat leads to numerous health issues. Investigating the role played by fat or adipose tissue is significant to get a better understanding of obesity and other problems.

17 Dec 2021

Experts grow novel cell lines in a chemically defined medium

Researchers for the first time acquired stem cells from livestock that was grown under chemically defined conditions.

13 Dec 2021

Powering the Biotechnology Revolution through Cloud R&D

In this interview, we speak to Sajith Wickramasekara, CEO and Co-Founder of Benchling, about cloud R&D and how it is powering the biotechnology revolution.

From Benchling 10 Dec 2021

Researchers come up with a novel technique to produce single-sex litters

Researchers from the Francis Crick Institute along with the University of Kent utilized gene-editing technology to produce male-only and female-only mice litter with 100% efficacy.

7 Dec 2021

New CRISPR technology could improve diagnostic tests for COVID-19

A new type of CRISPR platform that leverages the benefits of a compact RNA-editing protein could result in enhanced diagnostic tests for COVID-19.

2 Dec 2021

Researchers identify new route to produce complex antibiotics

Researchers recently discovered a novel route to produce complex antibiotics taking advantage of gene editing to re-program pathways to future medicines.

From The University of Manchester 2 Dec 2021

CRISPR introduces potentially dangerous changes in cells, reveals research

New research revealed that gene editing, particularly gene knockout, with CRISPR-Cas9 can support cells with mutated gene forms associated with cancer.

15 Nov 2021

Researchers identify a gene in wheat with profound effects on the production of seeds

Scientists from the John Innes Centre have identified a gene that has deep-rooted effects on seed production in wheat.

10 Nov 2021

Genetic analysis reveals the deep homology between fins and limbs

All vertebrates have the same basic body plan: head, spine, four appendages. Those appendages vary greatly in size, shape, and function, of course -; from fins to wings, arms, and legs -; but a new genetic analysis shows that genes that control development at the ends of the appendages share a deep evolutionary history.

9 Nov 2021

Study employs engineered base editors for controllable genome editing

According to a recent study, targeted mutations to the genome can be instituted by splitting specific mutator enzymes and later inducing them to reconstitute.

1 Nov 2021