Heart Disease News and Research

RSS

Genetic risk score may help identify Type 2 diabetes patients with a higher risk for cardiovascular events

A risk score based on a gene map predicted the likelihood of high blood pressure leading to heart problems or stroke in people with Type 2 diabetes, according to a study published today in the American Heart Association's peer-reviewed journal Hypertension.

5 Apr 2022

Experimental "gene silencing" therapy reduces a important driver of heart disease risk by up to 98%

Findings from a new Cleveland Clinic-led phase 1 trial show that an experimental "gene silencing" therapy reduced blood levels of lipoprotein(a), a key driver of heart disease risk, by up to 98%.

4 Apr 2022

Understanding how cleaning up bad mitochondria affects stem cell division

Most of us remember enough biology to recall that mitochondria are known as "the powerhouse of the cell." Even that audacious term may downplay the importance of mitochondria and what happens when mitochondria go bad.

1 Apr 2022

Study on key protein offers clues into the origin of mesothelioma

Researchers at the University of Colorado Anschutz Medical Campus and their international collaborators have discovered that a protein critical in the embryonic stages of life is reactivated in certain cases of mesothelioma, offering clues into the origin of this aggressive cancer.

30 Mar 2022

Researchers reveal how deleting a protein could prevent heart attacks and strokes

Macrophages travel through our arteries, gobbling fat the way Pac-man gobbled ghosts. But fat-filled macrophages can narrow blood vessels and cause heart disease.

29 Mar 2022

Researchers analyze a powerful tool to enhance drug discovery

Hormones or chemical messengers link to cell membrane receptors to tweak how the cell responds, creating a metaphorical interaction and traffic network on the surface of cell membranes inside human body.

23 Mar 2022

Microbial communities with auxotrophs more likely to have increased drug tolerance, study finds

Research from the Francis Crick Institute has revealed a key mechanism which increases tolerance to drugs amongst microbial communities.

22 Mar 2022

Researchers create a mobile app to calculate genetic risk for coronary artery disease

A Scripps Research team developed a smartphone app that can calculate users' genetic risk for coronary artery disease (CAD)-; and found that users at high risk sought out appropriate medication after using the app.

15 Mar 2022

Cellular therapy leads to meaningful functional improvements in DMD patients

A clinical trial at UC Davis Health and six other sites showed that a cellular therapy offers promise for patients with late-stage Duchenne muscular dystrophy (DMD), a rare genetic disorder causing muscle loss and physical impairments in young people.

From The University of California, Davis 14 Mar 2022

Unusual partners aid new blood vessel development

Insufficient oxygen to an area like the heart or legs, called hypoxia, is a cue to our bodies to make more blood vessels, and scientists have found some unusual partners are key to making that happen.

9 Mar 2022

Researchers observe cellular rejuvenation therapy securely promoting reverse aging in mice

Researchers at Salk observed no rise in cancer or other health problems in mice treated with an anti-aging regimen at the beginning of their middle age.

8 Mar 2022

UTSA team develops innovative inhibitor to fight obesity and heart disease

An interdisciplinary research team at The University of Texas at San Antonio has successfully developed an innovative inhibitor that shows promise in fighting obesity and potentially preventing heart disease.

4 Mar 2022

Researchers employ genetic testing to determine the risk of developing cardiovascular disease

Dignity Health in Arizona is introducing the first research study in North America that will use genetic testing to pinpoint men and women who are at risk of developing a cardiovascular disease based on the composition of their DNA.

22 Feb 2022

Experts identify critical genes that cause coronary heart disease and trigger heart attacks

Recent research identified the major genes involved in coronary heart disease and cardiac arrest.

21 Feb 2022

Why is it Important to have Diverse Genomics Data in Science?

In this interview, we speak to Dr. Santiago Miriuka, CEO of MultiplAI Health, about the importance of having diverse genomics data in research.

From MultiplAI Health 17 Feb 2022

Identification of a bivalent histone-mark switch essential for angiogenesis

Defying conventional epigenomic wisdom, the non-conventional polycomb (PRC)1 variant paradoxically overwhelms the conventional PRC-mediated gene silencing in activated endothelial cells.

9 Feb 2022

New model could improve the assessment of heart disease

A heart attack or stroke can blindside people who thought they were at low risk. Now, research led by UConn Health has found a new model that could improve how we assess heart disease.

1 Feb 2022

Study offers insight into how activated protein C may protect aging patients from reperfusion injury

A University of South Florida Health (USF Health) preclinical study offers molecular insight into how activated protein C (APC) may improve aging patients' tolerance to reperfusion injury – a potentially adverse effect of treatment for ischemic heart disease.

1 Feb 2022

An Interview with The Million Veteran Program (MVP)

In this interview, we speak to Dr. Sumitra Muralidhar, the Program Director for VA’s Million Veteran Program (MVP) about the program and its aims for veterans.

28 Jan 2022

Study investigates the proteins influencing the aging process

Scientists identified two blood proteins that positively influence human health and lifespan.

27 Jan 2022