Nucleic Acid News and Research

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Researchers determine 3D structures of RNA hybridization with artificial nucleic acids

As medical research progresses, traditional treatment protocols are being rapidly exhausted. New approaches to treat diseases that do not respond to conventional drugs are the need of the hour.

4 Dec 2020

Study underlines the significance of epithelial against invasive pathogens

Researchers have demonstrated that a protein present in skin cells detects a particular nucleic acid that is developed at the time of virus replication.

30 Nov 2020

Warwick researchers design computational model to enable drug predictions against COVID-19

A computational model of a human lung cell has been used to understand how SARS-CoV-2 draws on human host cell metabolism to reproduce by researchers at the University of Warwick.

From The University of Warwick 26 Nov 2020

Scientists identify potential targets against coronavirus

Scientists comprehensively studied the RNA genomic structure of the SARS-CoV-2 coronavirus.

11 Nov 2020

Highly automated device rapidly detects the presence of COVID-19

Throughout the pandemic, infectious disease experts and frontline medical workers have asked for a faster, cheaper and more reliable COVID-19 test.

6 Nov 2020

Porvair Sciences offers optimized microplate for SARS-CoV-2 nucleic acid purification

Porvair Sciences has introduced a new 2.2ml 96 deep well plate specifically designed to be fully compatible with the Thermo Scientific™ KingFisher™ range of nucleic acid purification systems.

From Porvair Sciences Limited 2 Nov 2020

Exploiting CRISPR systems for the fast detection of SARS-CoV-2

A paper published on medRxiv describes a repurposed type III CRISPR-Cas system that can detect the virus from nasopharyngeal swabs in less than an hour.

26 Oct 2020

Researchers develop a new method for siRNA stabilization

In the gene controlling mechanism, known as RNA interference, the expression of particular genes is downregulated by siRNAs or endogenic microRNAs.

19 Oct 2020

Krystal binding microplates set a new standard for uniform, reproducible capture of biomolecules

Porvair Sciences new medium and high bind Krystal microplates set a new standard for uniform and reproducible capture of a wide range of biomolecules ready for affinity binding assays such as ELISA's.

From Porvair Sciences Limited 16 Oct 2020

New machine learning algorithms to analyze reams of RNA-based 'toehold' sequences

DNA and RNA have been compared to "instruction manuals" containing the information needed for living "machines" to operate.

7 Oct 2020

Researchers develop low-cost CRISPR method to detect SARS-CoV-2

In March 2020, scientists started to design a new, cost-efficient, CRISPR-based diagnostic platform to spot infectious diseases, such as SARS-CoV-2.

22 Sep 2020

Combined point-of-care nucleic acid and antibody test can speed up COVID-19 detection

A Cambridge hospital has piloted the use of combined rapid point-of-care nucleic acid and antibody testing for SARS-CoV-2 infection after researchers at the University of Cambridge showed that this approach was superior to virus detection alone for diagnosing COVID-19 disease.

3 Sep 2020

Study shows efficacy of L-Grb2 in preclinical models of ovarian and uterine cancer

The cover for issue 29 of Oncotarget features Figure 5, "In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model," by Lara, et al. which reported that adaptor proteins such as growth factor receptor-bound protein-2 play important roles in cancer cell signaling.

23 Jul 2020

Researchers identify key enzyme that drives the production of ribosomes

Scientists have demonstrated that an enzyme fuels the production of ribosomes—the molecular machines that synthesize all cellular proteins.

From University of Toronto 17 Jul 2020

Researchers develop new immunotherapy that prevents reoccurrence of breast cancer

New immunotherapy developed by researchers at Northwestern University dramatically extends the survival time of mice with triple-negative breast cancer, one of the most aggressive and difficult-to-treat forms of breast cancer.

14 Jul 2020

New device can help test potential drug candidates for COVID-19

Scientists have created a human cell “membrane on a chip” that enables tracking of the interaction of drugs and infectious agents with the human cells.

6 Jul 2020

Researchers develop intracellular biopsy to isolate targeted miRNAs from living cells

MicroRNAs, are attracting interest relating to human diseases because variations in the expression of miRNAs are often associated with abnormal functions.

11 Jun 2020

Human protein plays crucial role in transcription and genome integrity

Researchers from the University of Seville and Cabimer discover that the UAP56/DDX39B protein remove DNA-RNA hybrids from the genome.

5 Jun 2020

EKF secures COVID-19 novel sample collection kit manufacturing and supply contracts

EKF Diagnostics, the global in vitro diagnostics company, announces it has secured new contracts for the manufacture and supply of a novel, patented sample collection device which allows COVID-19 samples to be rapidly inactivated in the collection tube, avoiding contamination and preserving RNA without need for refrigeration.

From EKF Diagnostics 26 May 2020

Entos and Precision NanoSystems to develop vaccines and therapeutics using NanoAssemblr GMP System

Entos Pharmaceuticals, a healthcare biotechnology company developing next generation nucleic acid medicines with their Fusogenix delivery platform announced today a partnership with Precision NanoSystems, Inc., (PNI), a global leader in enabling transformative nanomedicines, to produce clinical grade vaccines and therapeutics using PNI's NanoAssemblr GMP System.

7 May 2020