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Researchers understand the mystery behind DNA rings

Professor Dr Anton Henssen of Charité – Universitätsmedizin Berlin and the Helmholtz Association’s Max Delbrück Center (MDC) for Molecular Medicine, along with a group of researchers from the United States and the United Kingdom, have received a grant for a Cancer Grand Challenge.

17 Jun 2022

Researchers discover a new interferon-gamma receptor signaling pathway

The interferon-gamma receptor (IFNgR) signaling pathway has been identified to be crucial for the vulnerability of glioblastoma tumors to death by CAR T-cell immunotherapy, according to researchers at Massachusetts General Hospital (MGH).

10 Jun 2022

Origin of chromatin in ancient microbes happened 1–2 billion years ago, study reveals

Nature’s storage solution originally emerged in ancient microbes living on Earth around one and two billion years ago, according to researchers at the Center for Genomic Regulation (CRG).

10 Jun 2022

Microorganisms mediate Sphagnum peatmoss resilience to warming

Microorganisms may provide hope that peatlands can withstand hotter temperatures in a changing climate.

10 Jun 2022

Scientists discover that most synonymous mutations are strongly harmful

University of Michigan scientists reveal that most synonymous mutations are severely damaging in a study published in Nature that entailed genetic manipulation of yeast cells in the lab.

9 Jun 2022

Characterizing the genetic factors impacting the immune response in type 1 diabetes

A new study performed has offered better knowledge about how genetic factors tend to impact the immune response of the body in type 1 diabetes.

8 Jun 2022

Researchers develop GenoBaits Soy40K to assist soybean breeding and genetic study

Over a 5,000-year period, cultivated soybean was domesticated from wild soybean in China, and then extensively spread throughout the world. Soybean is a multipurpose crop that accounts for 56% of global oilseed production and more than 25% of protein used in food and animal feed.

7 Jun 2022

Research findings provide clues on the properties that might have made A. baumannii a successful pathogen

Over 670,000 people in Europe become ill each year as a result of pathogenic bacteria that are resistant to antibiotics, and 33,000 people die as a result of the diseases they cause. Pathogens that are resistant to multiple antibiotics at the same time are particularly dangerous.

6 Jun 2022

Study describes the importance of the autoimmune response in bacteria

CRISPR has made headlines in recent years for its potential to help patients with conditions as diverse as blindness and sickle cell disease. However, bacteria were already using CRISPR as an immune system to combat viruses long before humans adopted it to combat genetic disorders.

3 Jun 2022

Study identifies the regulatory function of non-coding 7S RNA

In human cells, a non-coding RNA molecule controls mitochondrial gene expression, according to new research published in the journal Cell. The research is the result of a collaboration between Sweden’s University of Gothenburg and Karolinska Institutet, as well as Germany’s University of Cologne.

3 Jun 2022

Vienna researchers aim to solve a great mystery of human evolution

Using the latest scientific methods, Tom Higham and Katerina Douka from the University of Vienna want to solve a great mystery of human evolution: Why are we the only humans left? Higham and Douka were the first ones to find a first-generation offspring of two different types of human. They continuously publish new results in high impact journals, most recently in Science Advances.

3 Jun 2022

Researchers reveal that new compact version of Cas7-11 enzyme improves RNA editing

Cas7-11, the first CRISPR enzyme that can make precise, directed cuts to strands of RNA without hurting cells, was identified and described last year by researchers at MIT’s McGovern Institute for Brain Research.

From Massachusetts Institute of Technology (MIT) 2 Jun 2022

Study shows how genetic database offers strong implications for chimpanzee conservation

Chimpanzees live in the savannahs and forests of tropical Africa. In contrast to the hominid sites that have been preserved to this day—mostly in caves and temperate climates—chimpanzee habitats have produced few specimens that have been preserved or discovered in the archaeological record.

2 Jun 2022

Study reveals how RNAi workhorse protein optimizes to keep protein synthesis on track

Proteins are made in cells in the same way as they are made in factories. However, making too much at the wrong moment may lead to illnesses like cancer, so they use RNA interference (RNAi) to regulate production.

1 Jun 2022

Researchers analyze the involvement of immune cells in lung cancer survival

Lung cancer affects approximately 48,500 persons in the United Kingdom every year. New treatments are urgently needed because only around 20% of patients live 5 years after diagnosis, and it is the leading cause of cancer death.

1 Jun 2022

Research shows how current drugs impact bacterial physiology

Tuberculosis is a stubborn disease caused by even more stubborn bacteria. While many bacterial infections clear up within days of taking antibiotics, TB can take up to six months to clear up and, in some cases, never leave the human body. In 2020, it claimed 1.5 million lives, second only to COVID-19 in terms of infectious disease deaths.

1 Jun 2022

seqWell and Element Biosciences partner to demonstrate sequencing performance of multiplexed plexWell technology with the AVITI System

seqWell today announced a partnership with Element Biosciences Inc., developer of the Element AVITI™ System.

From Element Biosciences 1 Jun 2022

Study highlights the interaction between single-stranded DNA and the linker histone H1

Human DNA is neatly locked in place around a central disc in the tight quarters of the cell nucleus by H1 linker histone that helps shepherd DNA into the tidy chromatin fibers that make up chromosomes. The linker histone, on the other hand, is much more than a protein clip.

31 May 2022

Endogenous retroviruses in the human genome are likely to pose a risk in regenerative medicine

Scientists from Kumamoto University used next-generation sequencing to analyze human endogenous retrovirus (HERV) integration sites and found that these primitive retroviruses can retrotranspose (DNA sequence insertion with RNA mediation) into iPS cells.

31 May 2022

Fast-breeding sea urchin species may be a game changer in genetic research

Many people may not realize that the humble sea urchin is a titan when it comes to the study of biology. Now, researchers from Japan have discovered that sea urchins could help biological studies go further than ever before.

30 May 2022

Genome News and Research

Researchers understand the mystery behind DNA rings

Researchers discover a new interferon-gamma receptor signaling pathway

Origin of chromatin in ancient microbes happened 1–2 billion years ago, study reveals

Microorganisms mediate Sphagnum peatmoss resilience to warming

Scientists discover that most synonymous mutations are strongly harmful

Characterizing the genetic factors impacting the immune response in type 1 diabetes

Researchers develop GenoBaits Soy40K to assist soybean breeding and genetic study

Research findings provide clues on the properties that might have made A. baumannii a successful pathogen

Study describes the importance of the autoimmune response in bacteria

Study identifies the regulatory function of non-coding 7S RNA

Vienna researchers aim to solve a great mystery of human evolution

Researchers reveal that new compact version of Cas7-11 enzyme improves RNA editing

Study shows how genetic database offers strong implications for chimpanzee conservation

Study reveals how RNAi workhorse protein optimizes to keep protein synthesis on track

Researchers analyze the involvement of immune cells in lung cancer survival

Research shows how current drugs impact bacterial physiology

seqWell and Element Biosciences partner to demonstrate sequencing performance of multiplexed plexWell technology with the AVITI System

Study highlights the interaction between single-stranded DNA and the linker histone H1

Endogenous retroviruses in the human genome are likely to pose a risk in regenerative medicine

Fast-breeding sea urchin species may be a game changer in genetic research

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