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Alzheimer’s patients tend to have differed and increased genetic changes, says study

Errors present in DNA can get accumulated inside brain cells as one is aging. However, in patients with Alzheimer’s disease, these errors called somatic mutations may increase at a quicker rate.

21 Apr 2022

Researchers analyze single-cell DNA sequencing for having a significant role in Alzheimer’s disease

The loss of functional neurons in the brain is a characteristic of Alzheimer’s disease. What, on the other hand, is the source of this loss?

21 Apr 2022

Researchers may have identified a key intermediate in the transition from prokaryotes to eukaryotes

All modern organisms fall into two classes, eukaryotes and prokaryotes. Eukaryotes (from the Greek meaning "true kernel") have a cell nucleus that harbors most of the cell's genetic information and includes organisms such as humans, plants and fungi.

20 Apr 2022

Genomics provides a deeper understanding of the cause of hydrocephalus

The cerebral ventricles—four linked cavities of the brain that are packed with cerebrospinal fluid—become enlarged in hydrocephalus, or “water on the brain;” however, the cause is unknown in many instances.

20 Apr 2022

Study identifies new targets for treating sorafenib-resistant hepatocellular carcinoma using CRISPR-Cas9 screening

This study is led by Xiujun Cai (Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine). Professor Xiujun Cai's research team screened the whole genome of hepatocellular carcinoma cells (HepG2) through CRISPR / cas9 system under sorafenib treatment, and screened the dominant gene in sorafenib resistance.

20 Apr 2022

Deeper understanding of genomics support researchers discover new perceptions

In genomic studies, researchers look at a population’s DNA to figure out how genetics affects health and disease.

20 Apr 2022

Scientists discover an effective drug development candidate from rare actinomycetes

Researchers are rushing to review a group of bacteria known as actinomycetes, which are one of the most successful sources of treatment.

19 Apr 2022

Researchers use CRISPR gene editing tool to analyze globin gene switching

CRISPR gene editing—a form of “molecular scissors”—was used by UNSW researchers to investigate how deletions in one section of the genome might impact the expression of surrounding genes.

From The University of New South Wales (UNSW) 19 Apr 2022

From Test Tube to Cell; Creating Biological Computers from RNA

In this interview, we speak to Dr. Sam Schaffter about his latest research that looked at creating biological computers using RNA and their role within research.

From National Institute of Standards and Technology (NIST) 18 Apr 2022

Spatial maps offer insights into the battle between melanoma cells and immune cells

Melanoma is a somewhat unusual cancer-;one that blooms before our very eyes, often on sun-exposed skin, and can quickly become deadly as it turns our own skin against us and spreads to other organs.

From Harvard Medical School 15 Apr 2022

A single mutation can enhance the virulence of Zika virus

Researchers at La Jolla Institute for Immunology (LJI) have found that Zika virus can mutate to become more infective-;and potentially break through pre-existing immunity.

13 Apr 2022

Max Planck researchers reveal the structure of kinetochore corona

During cell division in a mother cell, the 23 chromosomes that carry the human genome must be first copied and later delivered to two newly forming daughter cells.

From The Max Planck Institute 11 Apr 2022

Researchers discover a mechanism by which the protein DELE1 detects organelle stress

Researchers have long speculated an association between disorders in mitochondria, tiny organelles inside the cell, and the aging process and age-related illnesses.

11 Apr 2022

Researchers develop a universal AI algorithm for deep clean-up of single cell genomic data

A single cell’s genome or transcriptome can reveal considerably more data about its place in biological systems than sequencing a full batch of cells, just as interviewing a single person about their health will provide specialized, personalized information hard to obtain from a big poll.

11 Apr 2022

Researchers identify specific genes that cause schizophrenia

A substantial number of individual genes that potentially play essential roles in schizophrenia have been uncovered in the largest-ever genomic analysis of the psychiatric condition.

11 Apr 2022

Researchers identify a large number of specific genes associated with schizophrenia

What is the role of genetics in schizophrenia? To address this question, an international group of researchers led by Charité – Universitätsmedizin Berlin and Cardiff University developed and conducted the largest-ever genetic study on schizophrenia.

8 Apr 2022

New technique helps rewind the cellular biological clock by around 30 years

Research from the Babraham Institute has developed a method to 'time jump' human skin cells by 30 years, turning back the aging clock for cells without losing their specialized function.

8 Apr 2022

Study sheds light on genetic causes of Alzheimer’s disease and other dementias

If we want to enhance our knowledge and treatment of Alzheimer’s disease, we need to identify genetic risk factors.

7 Apr 2022

Study discovers links between DNA methylation and gene expression in children

A new study headed by ISGlobal, an organization financed by “Ia Caixa” Foundation, finds links between DNA methylation patterns and gene expression levels in blood samples from youngsters.

7 Apr 2022

Researchers discover 15 genetic 'hotspots' that speed up or slow down brain aging

Researchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow it down -; a finding that could provide new drug targets to resist Alzheimer's disease and other degenerative brain disorders, as well as developmental delays.

6 Apr 2022

Genome News and Research

Alzheimer’s patients tend to have differed and increased genetic changes, says study

Researchers analyze single-cell DNA sequencing for having a significant role in Alzheimer’s disease

Researchers may have identified a key intermediate in the transition from prokaryotes to eukaryotes

Genomics provides a deeper understanding of the cause of hydrocephalus

Study identifies new targets for treating sorafenib-resistant hepatocellular carcinoma using CRISPR-Cas9 screening

Deeper understanding of genomics support researchers discover new perceptions

Scientists discover an effective drug development candidate from rare actinomycetes

Researchers use CRISPR gene editing tool to analyze globin gene switching

From Test Tube to Cell; Creating Biological Computers from RNA

Spatial maps offer insights into the battle between melanoma cells and immune cells

A single mutation can enhance the virulence of Zika virus

Max Planck researchers reveal the structure of kinetochore corona

Researchers discover a mechanism by which the protein DELE1 detects organelle stress

Researchers develop a universal AI algorithm for deep clean-up of single cell genomic data

Researchers identify specific genes that cause schizophrenia

Researchers identify a large number of specific genes associated with schizophrenia

New technique helps rewind the cellular biological clock by around 30 years

Study sheds light on genetic causes of Alzheimer’s disease and other dementias

Study discovers links between DNA methylation and gene expression in children

Researchers discover 15 genetic 'hotspots' that speed up or slow down brain aging

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